SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jhe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1jhe LEXA REPRESSOR
(Escherichia
coli) 		5 / 12 VAL A 133
THR A 154
LEU A 167
VAL A 139
PHE A 186
 None
 0.89A 2jn3A-1jheA:
undetectable		 2jn3A-1jheA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 1jhe LEXA REPRESSOR
(Escherichia
coli) 		4 / 7 ILE A 188
PRO A  87
ILE A 177
ILE A 149
 None
 0.88A 2q83A-1jheA:
undetectable		 2q83A-1jheA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD2_1
(CYTOCHROME P450 2D6)		 1jhe LEXA REPRESSOR
(Escherichia
coli) 		5 / 9 PHE A 186
LEU A 158
VAL A 145
THR A 136
ILE A 188
 None
 0.99A 3tbgD-1jheA:
0.0		 3tbgD-1jheA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1R_A_LZUA801_1
(MUCOSA-ASSOCIATED
LYMPHOID TISSUE
LYMPHOMA
TRANSLOCATION
PROTEIN 1)		 1jhe LEXA REPRESSOR
(Escherichia
coli) 		5 / 12 LEU A  76
VAL A 100
ALA A 109
LEU A 131
LEU A 130
 None
 1.18A 4i1rA-1jheA:
undetectable		 4i1rA-1jheA:
16.80