SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jhh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WG7_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1jhh	LEXA REPRESSOR (Escherichia coli)	4 / 6	ILE A 15 ARG A 7 THR A 5 LEU A 4	None	0.94A	3wg7N-1jhhA: undetectable 3wg7W-1jhhA: undetectable	3wg7N-1jhhA: 16.33 3wg7W-1jhhA: 13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1B_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1jhh	LEXA REPRESSOR (Escherichia coli)	4 / 7	ILE A 15 ARG A 7 THR A 5 LEU A 4	None	0.87A	5b1bN-1jhhA: undetectable 5b1bW-1jhhA: 0.0	5b1bN-1jhhA: 16.33 5b1bW-1jhhA: 13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XOO_B_ADNB503_1 (GLYCOSAMINOGLYCAN XYLOSYLKINASE)	1jhh	LEXA REPRESSOR (Escherichia coli)	4 / 5	LEU A 113 VAL A 146 GLU A 189 LEU A 88	None	1.08A	5xooB-1jhhA: 0.0	5xooB-1jhhA: 16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BXN_A_SAMA901_0 (DIPHTHAMIDE BIOSYNTHESIS ENZYME DPH2)	1jhh	LEXA REPRESSOR (Escherichia coli)	5 / 12	VAL A 179 ARG A 148 ILE A 149 ASP A 151 ASP A 150	None	1.35A	6bxnA-1jhhA: undetectable	6bxnA-1jhhA: 19.57

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3WG7_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1jhh","LEXA REPRESSOR","Escherichia coli",4,"ILE A  15;ARG A   7;THR A   5;LEU A   4","None","0.94A","3wg7N-1jhhA:undetectable;3wg7W-1jhhA:undetectable","3wg7N-1jhhA:16.33;3wg7W-1jhhA:13.09"],["5B1B_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1jhh","LEXA REPRESSOR","Escherichia coli",4,"ILE A  15;ARG A   7;THR A   5;LEU A   4","None","0.87A","5b1bN-1jhhA:undetectable;5b1bW-1jhhA:0.0","5b1bN-1jhhA:16.33;5b1bW-1jhhA:13.09"],["5XOO_B_ADNB503_1","GLYCOSAMINOGLYCAN XYLOSYLKINASE","1jhh","LEXA REPRESSOR","Escherichia coli",4,"LEU A 113;VAL A 146;GLU A 189;LEU A  88","None","1.08A","5xooB-1jhhA:0.0","5xooB-1jhhA:16.15"],["6BXN_A_SAMA901_0","DIPHTHAMIDE BIOSYNTHESIS ENZYME DPH2","1jhh","LEXA REPRESSOR","Escherichia coli",5,"VAL A 179;ARG A 148;ILE A 149;ASP A 151;ASP A 150","None","1.35A","6bxnA-1jhhA:undetectable","6bxnA-1jhhA:19.57"]]