SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jhj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1jhj APC10
(Homo
sapiens) 		5 / 12 ILE A 108
ILE A  79
LEU A  77
ILE A 137
ILE A 156
 None
 1.06A 1oipA-1jhjA:
undetectable		 1oipA-1jhjA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1jhj APC10
(Homo
sapiens) 		4 / 7 ILE A  94
PRO A  13
GLY A 118
TRP A 119
 None
 0.95A 2pnjB-1jhjA:
undetectable		 2pnjB-1jhjA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 1jhj APC10
(Homo
sapiens) 		4 / 7 ILE A 137
ILE A 120
LEU A 111
ILE A  94
 None
 0.86A 2q83A-1jhjA:
undetectable		 2q83A-1jhjA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7B_C_ACTC513_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1jhj APC10
(Homo
sapiens) 		3 / 3 TYR A  53
HIS A 152
ARG A 154
 None
 0.67A 4e7bC-1jhjA:
undetectable		 4e7bC-1jhjA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_B_FUAB1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1jhj APC10
(Homo
sapiens) 		4 / 5 ILE A 120
LEU A  45
HIS A  62
VAL A 141
 None
 0.95A 5jmnB-1jhjA:
0.0		 5jmnB-1jhjA:
10.13