SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jhk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_2
(PROTEASE)		 1jhk IG GAMMA-1-CHAIN
(Mus
musculus) 		5 / 12 LEU H 138
VAL H 163
GLY H 157
VAL H 183
VAL H 181
 None
 0.87A 2ieoB-1jhkH:
undetectable		 2ieoB-1jhkH:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 1jhk IG GAMMA-1-CHAIN
(Mus
musculus) 		3 / 3 TYR H 175
GLY H 144
PHE H 146
 None
 0.70A 2m2pB-1jhkH:
undetectable		 2m2pB-1jhkH:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1jhk IG GAMMA-1-CHAIN
(Mus
musculus) 		3 / 3 SER H 203
ALA H 198
VAL H 197
 None
 0.58A 5eypA-1jhkH:
undetectable		 5eypA-1jhkH:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1jhk IG GAMMA-1-CHAIN
(Mus
musculus) 		3 / 3 SER H  25
ALA H  24
THR H  94
 None
 0.74A 5n0xB-1jhkH:
0.0		 5n0xB-1jhkH:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1jhk IG GAMMA-1-CHAIN
(Mus
musculus) 		5 / 12 LEU H  45
VAL H  37
TRP H  50
TRP H  95
GLY H  49
 None
 1.19A 5tzoB-1jhkH:
undetectable		 5tzoB-1jhkH:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA813_0
(GEPHYRIN)		 1jhk IG GAMMA-1-CHAIN
(Mus
musculus) 		3 / 3 THR H  76
ALA H  24
LYS H   2
 None
 0.78A 6fgcA-1jhkH:
undetectable		 6fgcA-1jhkH:
17.62