SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jhl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 1jhl IGG1-KAPPA D11.15 FV
(HEAVY CHAIN)
IGG1-KAPPA D11.15 FV
(LIGHT CHAIN)
(Mus
musculus) 		8 / 12 TYR L  36
GLN L  89
TYR L  94
PHE L  98
TRP H  33
ASN H  35
VAL H  37
ASN H  50
 None
 0.48A 1h8sA-1jhlL:
21.3		 1h8sA-1jhlL:
54.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 1jhl IGG1-KAPPA D11.15 FV
(LIGHT CHAIN)
(Mus
musculus) 		5 / 12 LEU L  73
THR L  20
LEU L 104
ILE L  87
GLY L 101
 None
 0.98A 1qknA-1jhlL:
undetectable		 1qknA-1jhlL:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 1jhl IGG1-KAPPA D11.15 FV
(LIGHT CHAIN)
(Mus
musculus) 		5 / 12 ASP L  70
ILE L  87
ASN L  22
LEU L  73
THR L 102
 None
 1.12A 3eeyF-1jhlL:
undetectable		 3eeyF-1jhlL:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA1_1
(CYTOCHROME P450 2D6)		 1jhl IGG1-KAPPA D11.15 FV
(LIGHT CHAIN)
(Mus
musculus) 		5 / 12 PHE L  62
GLY L  16
LEU L  78
GLU L  79
SER L  76
 None
 1.35A 3tbgA-1jhlL:
undetectable		 3tbgA-1jhlL:
13.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 1jhl IGG1-KAPPA D11.15 FV
(HEAVY CHAIN)
(Mus
musculus) 		4 / 5 VAL H   2
TYR H  27
ARG H  98
TYR H 107
 None
 0.41A 4m7kH-1jhlH:
22.8		 4m7kH-1jhlH:
72.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 1jhl IGG1-KAPPA D11.15 FV
(HEAVY CHAIN)
(Mus
musculus) 		4 / 5 GLN H  82
LEU H  83
SER H  85
ASP H  66
 None
 1.23A 4qtuD-1jhlH:
undetectable		 4qtuD-1jhlH:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 1jhl IGG1-KAPPA D11.15 FV
(HEAVY CHAIN)
(Mus
musculus) 		3 / 3 THR H  28
SER H  31
TYR H  32
 None
 0.83A 5jsdA-1jhlH:
0.0		 5jsdA-1jhlH:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 1jhl IGG1-KAPPA D11.15 FV
(HEAVY CHAIN)
(Mus
musculus) 		3 / 3 THR H  28
SER H  31
TYR H  32
 None
 0.83A 5jsdB-1jhlH:
2.7		 5jsdB-1jhlH:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 1jhl IGG1-KAPPA D11.15 FV
(HEAVY CHAIN)
(Mus
musculus) 		3 / 3 THR H  28
SER H  31
TYR H  32
 None
 0.83A 5jsdC-1jhlH:
2.7		 5jsdC-1jhlH:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 1jhl IGG1-KAPPA D11.15 FV
(HEAVY CHAIN)
(Mus
musculus) 		3 / 3 THR H  28
SER H  31
TYR H  32
 None
 0.84A 5jseA-1jhlH:
2.3		 5jseA-1jhlH:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 1jhl IGG1-KAPPA D11.15 FV
(HEAVY CHAIN)
(Mus
musculus) 		3 / 3 THR H  28
SER H  31
TYR H  32
 None
 0.84A 5jseB-1jhlH:
2.7		 5jseB-1jhlH:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 1jhl IGG1-KAPPA D11.15 FV
(HEAVY CHAIN)
(Mus
musculus) 		3 / 3 THR H  28
SER H  31
TYR H  32
 None
 0.84A 5jseC-1jhlH:
2.7		 5jseC-1jhlH:
10.31