SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jhn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MX1_D_THAD4_2 (LIVER CARBOXYLESTERASE I)	1jhn	CALNEXIN (Canis lupus)	3 / 3	PHE A 436 LEU A 425 MET A 189	None	0.68A	1mx1D-1jhnA: undetectable	1mx1D-1jhnA: 19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UHO_A_VDNA1000_1 (CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE)	1jhn	CALNEXIN (Canis lupus)	5 / 10	TYR A 151 PHE A 436 LEU A 123 GLY A 158 PHE A 155	None	1.48A	1uhoA-1jhnA: undetectable	1uhoA-1jhnA: 21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IV6_C_SAMC301_1 (PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE)	1jhn	CALNEXIN (Canis lupus)	3 / 3	SER A 67 ASP A 454 ASP A 444	None	0.94A	3iv6C-1jhnA: undetectable	3iv6C-1jhnA: 21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5U4S_B_BEZB301_0 (PUTATIVE SHORT CHAIN DEHYDROGENASE)	1jhn	CALNEXIN (Canis lupus)	4 / 8	SER A 133 ILE A 85 LEU A 177 LEU A 169	None	1.03A	5u4sB-1jhnA: undetectable	5u4sB-1jhnA: 19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X23_A_LSNA502_1 (CYTOCHROME P450 2C9)	1jhn	CALNEXIN (Canis lupus)	5 / 12	PHE A 190 LEU A 238 VAL A 448 LEU A 227 LEU A 201	None	1.27A	5x23A-1jhnA: undetectable	5x23A-1jhnA: 21.50

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1MX1_D_THAD4_2","LIVER CARBOXYLESTERASE I","1jhn","CALNEXIN","Canis lupus",3,"PHE A 436;LEU A 425;MET A 189","None","0.68A","1mx1D-1jhnA:undetectable","1mx1D-1jhnA:19.97"],["1UHO_A_VDNA1000_1","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE","1jhn","CALNEXIN","Canis lupus",5,"TYR A 151;PHE A 436;LEU A 123;GLY A 158;PHE A 155","None","1.48A","1uhoA-1jhnA:undetectable","1uhoA-1jhnA:21.03"],["3IV6_C_SAMC301_1","PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE","1jhn","CALNEXIN","Canis lupus",3,"SER A  67;ASP A 454;ASP A 444","None","0.94A","3iv6C-1jhnA:undetectable","3iv6C-1jhnA:21.16"],["5U4S_B_BEZB301_0","PUTATIVE SHORT CHAIN DEHYDROGENASE","1jhn","CALNEXIN","Canis lupus",4,"SER A 133;ILE A  85;LEU A 177;LEU A 169","None","1.03A","5u4sB-1jhnA:undetectable","5u4sB-1jhnA:19.17"],["5X23_A_LSNA502_1","CYTOCHROME P450 2C9","1jhn","CALNEXIN","Canis lupus",5,"PHE A 190;LEU A 238;VAL A 448;LEU A 227;LEU A 201","None","1.27A","5x23A-1jhnA:undetectable","5x23A-1jhnA:21.50"]]