SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jhs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA154_1
(CALMODULIN)		 1jhs MOG1 PROTEIN
(Saccharomyces
cerevisiae) 		5 / 10 GLU A 190
LEU A 123
LEU A 178
GLU A 182
GLU A 181
 None
 1.09A 1a29A-1jhsA:
undetectable		 1a29A-1jhsA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 1jhs MOG1 PROTEIN
(Saccharomyces
cerevisiae) 		3 / 3 ASN A  84
ALA A  82
ARG A 194
 None
 0.80A 3tj7C-1jhsA:
3.0
3tj7D-1jhsA:
4.3		 3tj7C-1jhsA:
21.46
3tj7D-1jhsA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1jhs MOG1 PROTEIN
(Saccharomyces
cerevisiae) 		4 / 9 GLU A 182
LEU A 123
LEU A 137
ILE A 156
 None
 0.93A 4xtaA-1jhsA:
undetectable		 4xtaA-1jhsA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)		 1jhs MOG1 PROTEIN
(Saccharomyces
cerevisiae) 		6 / 12 VAL A 108
ALA A 103
PHE A 134
VAL A 158
GLY A 157
ILE A 156
 None
 1.46A 5j2tC-1jhsA:
undetectable		 5j2tC-1jhsA:
18.28