SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ji0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 1ji0 ABC TRANSPORTER
(Thermotoga
maritima) 		5 / 12 PHE A 125
VAL A  85
VAL A 180
ILE A 181
ILE A  33
 None
 0.94A 1epbA-1ji0A:
undetectable		 1epbA-1ji0A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 1ji0 ABC TRANSPORTER
(Thermotoga
maritima) 		5 / 12 PHE A 125
VAL A  85
VAL A 180
ILE A 181
ILE A  33
 None
 0.93A 1epbB-1ji0A:
undetectable		 1epbB-1ji0A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 1ji0 ABC TRANSPORTER
(Thermotoga
maritima) 		4 / 6 LEU A   6
VAL A   8
ILE A  62
ILE A  82
 None
 0.82A 2piwA-1ji0A:
undetectable		 2piwA-1ji0A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1ji0 ABC TRANSPORTER
(Thermotoga
maritima) 		4 / 6 VAL A 231
ILE A  33
ALA A 198
LEU A 236
 None
 0.81A 3kk6B-1ji0A:
0.4		 3kk6B-1ji0A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_A_SAMA900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 1ji0 ABC TRANSPORTER
(Thermotoga
maritima) 		5 / 12 GLY A 208
GLY A 220
SER A 223
ALA A 201
HIS A 206
 None
 1.11A 4krhA-1ji0A:
undetectable		 4krhA-1ji0A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 1ji0 ABC TRANSPORTER
(Thermotoga
maritima) 		5 / 12 GLY A 208
GLY A 220
SER A 223
ALA A 201
HIS A 206
 None
 1.14A 4krhB-1ji0A:
2.1		 4krhB-1ji0A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1ji0 ABC TRANSPORTER
(Thermotoga
maritima) 		5 / 9 ALA A 222
VAL A 210
ALA A 198
ALA A 201
ILE A  37
 None
 1.10A 4lbgB-1ji0A:
undetectable		 4lbgB-1ji0A:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1ji0 ABC TRANSPORTER
(Thermotoga
maritima) 		4 / 6 LEU A 135
ASN A 100
LEU A 147
GLU A 143
 None
 1.16A 4nc3A-1ji0A:
undetectable		 4nc3A-1ji0A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 1ji0 ABC TRANSPORTER
(Thermotoga
maritima) 		4 / 6 LEU A  26
LEU A   6
GLU A   7
ILE A  62
 None
 0.97A 4ww7A-1ji0A:
0.0		 4ww7A-1ji0A:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 1ji0 ABC TRANSPORTER
(Thermotoga
maritima) 		3 / 3 LYS A  72
ILE A  77
ILE A  82
 None
 0.59A 4y0qA-1ji0A:
undetectable		 4y0qA-1ji0A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9Y_A_1N1A1001_2
(EPHRIN TYPE-A
RECEPTOR 2)		 1ji0 ABC TRANSPORTER
(Thermotoga
maritima) 		3 / 3 ILE A 149
ILE A  91
MET A 162
 None
 0.71A 5i9yA-1ji0A:
undetectable		 5i9yA-1ji0A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_0
(REGULATORY PROTEIN
TETR)		 1ji0 ABC TRANSPORTER
(Thermotoga
maritima) 		5 / 12 MET A 162
ALA A 148
LEU A 160
ILE A 184
ASP A 117
 None
 1.15A 5vlmA-1ji0A:
0.0		 5vlmA-1ji0A:
20.48