SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jif'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_H_NCAH489_0
(ADP-RIBOSYL CYCLASE)		 1jif BLEOMYCIN-BINDING
PROTEIN
(Streptomyces
verticillus) 		3 / 3 TRP A  78
PHE A  29
TRP A  23
 None
 1.46A 1r15H-1jifA:
undetectable		 1r15H-1jifA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 1jif BLEOMYCIN-BINDING
PROTEIN
(Streptomyces
verticillus) 		4 / 7 LEU A  48
PHE A  22
PHE A  29
ILE A  66
 None
 0.87A 2opxA-1jifA:
undetectable		 2opxA-1jifA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1jif BLEOMYCIN-BINDING
PROTEIN
(Streptomyces
verticillus) 		4 / 7 ALA A  13
ASN A 114
PRO A 111
ALA A 112
 None
 1.14A 2zgwA-1jifA:
0.7		 2zgwA-1jifA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1jif BLEOMYCIN-BINDING
PROTEIN
(Streptomyces
verticillus) 		4 / 6 ALA A  13
ASN A 114
PRO A 111
ALA A 112
 None
 1.18A 2zgwB-1jifA:
undetectable		 2zgwB-1jifA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 1jif BLEOMYCIN-BINDING
PROTEIN
(Streptomyces
verticillus) 		4 / 5 ASN A  19
PHE A  22
ALA A 112
GLY A 113
 None
 1.22A 3bcrA-1jifA:
undetectable		 3bcrA-1jifA:
10.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_D_STID1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1jif BLEOMYCIN-BINDING
PROTEIN
(Streptomyces
verticillus) 		4 / 6 VAL A  41
VAL A  68
VAL A 116
ILE A  46
 None
 0.96A 3mssD-1jifA:
undetectable		 3mssD-1jifA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 1jif BLEOMYCIN-BINDING
PROTEIN
(Streptomyces
verticillus) 		4 / 8 LEU A  27
PHE A 118
LEU A  48
ILE A  46
 None
 0.88A 5mzjA-1jifA:
undetectable		 5mzjA-1jifA:
13.59