SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jih'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 1jih DNA POLYMERASE ETA
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 230
SER A   2
TRP A 233
LEU A 183
LEU A 187
 None
 1.08A 1s19A-1jihA:
0.0		 1s19A-1jihA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 1jih DNA POLYMERASE ETA
(Saccharomyces
cerevisiae) 		4 / 4 LEU A 316
SER A 360
LEU A 346
LEU A 370
 None
 1.09A 1yajA-1jihA:
undetectable		 1yajA-1jihA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 1jih DNA POLYMERASE ETA
(Saccharomyces
cerevisiae) 		4 / 4 LEU A 370
SER A 360
LEU A 320
LEU A 346
 None
 1.12A 1yajA-1jihA:
undetectable		 1yajA-1jihA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_D_BEZD2385_0
(CES1 PROTEIN)		 1jih DNA POLYMERASE ETA
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 370
SER A 360
LEU A 320
LEU A 346
 None
 1.14A 1yajD-1jihA:
undetectable		 1yajD-1jihA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 1jih DNA POLYMERASE ETA
(Saccharomyces
cerevisiae) 		3 / 3 SER A 242
ARG A 249
GLN A 283
 None
 0.77A 2xnrA-1jihA:
3.2		 2xnrA-1jihA:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CV9_A_VDXA501_1
(CYTOCHROME P450-SU1)		 1jih DNA POLYMERASE ETA
(Saccharomyces
cerevisiae) 		5 / 9 VAL A 157
SER A 153
SER A 135
ILE A 252
ILE A 164
 None
 1.14A 3cv9A-1jihA:
undetectable		 3cv9A-1jihA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 1jih DNA POLYMERASE ETA
(Saccharomyces
cerevisiae) 		5 / 11 ALA A  66
ILE A  71
GLY A  70
LEU A  87
ALA A  80
 None
 1.06A 3kw2A-1jihA:
0.0		 3kw2A-1jihA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_B_ADNB300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 1jih DNA POLYMERASE ETA
(Saccharomyces
cerevisiae) 		5 / 11 ALA A  66
ILE A  71
GLY A  70
LEU A  87
ALA A  80
 None
 1.08A 3kw2B-1jihA:
undetectable		 3kw2B-1jihA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA452_1
(CYTOCHROME P450
164A2)		 1jih DNA POLYMERASE ETA
(Saccharomyces
cerevisiae) 		5 / 12 PRO A 206
LEU A 205
LEU A   9
LEU A 169
ASN A 189
 None
 1.04A 3r9cA-1jihA:
undetectable		 3r9cA-1jihA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG9_B_KANB305_1
(APH(2'')-ID)		 1jih DNA POLYMERASE ETA
(Saccharomyces
cerevisiae) 		4 / 8 ASP A  30
SER A 275
HIS A  28
ASP A 155
 None
 1.15A 3sg9B-1jihA:
undetectable		 3sg9B-1jihA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1jih DNA POLYMERASE ETA
(Saccharomyces
cerevisiae) 		3 / 3 SER A 110
GLY A 109
GLN A 118
 None
 0.58A 3v4tH-1jihA:
0.0		 3v4tH-1jihA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1jih DNA POLYMERASE ETA
(Saccharomyces
cerevisiae) 		4 / 7 SER A 242
GLY A 263
THR A 284
ILE A 285
 None
 0.95A 4acaC-1jihA:
undetectable		 4acaC-1jihA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 1jih DNA POLYMERASE ETA
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 190
PRO A 209
ILE A 208
ILE A 212
 None
 0.83A 4dtaB-1jihA:
undetectable		 4dtaB-1jihA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1jih DNA POLYMERASE ETA
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 322
PRO A 323
ARG A 379
 None
 0.75A 4klrB-1jihA:
undetectable		 4klrB-1jihA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_2
(NEURAMINIDASE)		 1jih DNA POLYMERASE ETA
(Saccharomyces
cerevisiae) 		4 / 5 LEU A  23
ASP A 235
TRP A 233
ILE A 212
 None
 1.19A 4mwrA-1jihA:
undetectable		 4mwrA-1jihA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 1jih DNA POLYMERASE ETA
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  10
ILE A 212
LEU A 183
ILE A 190
ASN A 198
 None
 1.18A 4o1eA-1jihA:
undetectable		 4o1eA-1jihA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 1jih DNA POLYMERASE ETA
(Saccharomyces
cerevisiae) 		4 / 8 SER A  22
LEU A  23
ASP A 234
ASP A 235
 None
 0.84A 4umjA-1jihA:
undetectable		 4umjA-1jihA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_C_08JC602_1
(CYTOCHROME P450 3A4)		 1jih DNA POLYMERASE ETA
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 161
ALA A  27
ILE A 285
LEU A 238
 None
 0.94A 5te8C-1jihA:
0.4		 5te8C-1jihA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_B_ECLB1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1jih DNA POLYMERASE ETA
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 413
PHE A 419
LEU A 416
ILE A 486
 None
 0.73A 6b5vA-1jihA:
undetectable
6b5vB-1jihA:
undetectable		 6b5vA-1jihA:
11.02
6b5vB-1jihA:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)		 1jih DNA POLYMERASE ETA
(Saccharomyces
cerevisiae) 		4 / 5 GLN A 283
THR A 284
THR A 267
LEU A 238
 None
 1.30A 6gbnB-1jihA:
undetectable		 6gbnB-1jihA:
25.75