SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jiu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		4 / 6 LEU A 324
ILE A 255
ARG A 269
TRP A 271
 None
None
UDP  A 353 (-3.9A)
None
 1.06A 1db1A-1jiuA:
0.0		 1db1A-1jiuA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		4 / 4 LEU A 324
ILE A 255
ARG A 269
TRP A 271
 None
None
UDP  A 353 (-3.9A)
None
 1.04A 1ie9A-1jiuA:
0.0		 1ie9A-1jiuA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX3_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		3 / 3 LYS A 259
ILE A 143
THR A 267
 None
None
UDP  A 353 ( 4.6A)
 0.78A 1rx3A-1jiuA:
2.1		 1rx3A-1jiuA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		5 / 12 GLY A   9
SER A  82
TYR A 121
LEU A 126
LEU A  42
 None
 1.42A 1zgyA-1jiuA:
undetectable		 1zgyA-1jiuA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		4 / 7 VAL A 200
PHE A 204
THR A 206
LYS A 230
 None
 1.14A 2kotA-1jiuA:
undetectable		 2kotA-1jiuA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		5 / 12 LEU A  35
ILE A  63
ILE A   5
ILE A  30
PHE A 160
 None
 1.03A 2ygoA-1jiuA:
0.0		 2ygoA-1jiuA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		4 / 5 LEU A 324
ILE A 255
ARG A 269
TRP A 271
 None
None
UDP  A 353 (-3.9A)
None
 1.12A 2zlcA-1jiuA:
0.0		 2zlcA-1jiuA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		5 / 12 GLY A   9
SER A  82
TYR A 121
LEU A 126
LEU A  42
 None
 1.25A 3g9eA-1jiuA:
0.0		 3g9eA-1jiuA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_PNTA901_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		5 / 12 TYR A 261
THR A  99
ASP A 100
GLY A 187
TYR A 186
 UDP  A 353 (-4.7A)
None
None
UDP  A 353 ( 4.2A)
None
 0.91A 3hiiA-1jiuA:
0.0		 3hiiA-1jiuA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_PNTB901_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		5 / 12 TYR A 261
THR A  99
ASP A 100
GLY A 187
TYR A 186
 UDP  A 353 (-4.7A)
None
None
UDP  A 353 ( 4.2A)
None
 0.90A 3hiiB-1jiuA:
0.0		 3hiiB-1jiuA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		4 / 5 PHE A  51
LEU A  62
THR A  23
VAL A  12
 None
 1.03A 3wrkD-1jiuA:
0.0		 3wrkD-1jiuA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		5 / 12 GLY A   9
SER A  82
TYR A 121
LEU A 126
LEU A  42
 None
 1.40A 4emaA-1jiuA:
undetectable		 4emaA-1jiuA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_A_MTXA201_2
(DIHYDROFOLATE
REDUCTASE)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		3 / 3 LYS A 259
ILE A 143
THR A 267
 None
None
UDP  A 353 ( 4.6A)
 0.81A 4gh8A-1jiuA:
2.0		 4gh8A-1jiuA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		4 / 8 ILE A 256
ILE A 210
PHE A 212
GLY A 214
 None
None
None
UDP  A 353 (-3.2A)
 0.90A 4hb6A-1jiuA:
undetectable		 4hb6A-1jiuA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		4 / 8 ILE A 256
ILE A 210
PHE A 212
GLY A 214
 None
None
None
UDP  A 353 (-3.2A)
 0.80A 4hb8A-1jiuA:
undetectable		 4hb8A-1jiuA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		4 / 8 ILE A 256
ILE A 210
PHE A 212
GLY A 214
 None
None
None
UDP  A 353 (-3.2A)
 0.96A 4hdlA-1jiuA:
undetectable		 4hdlA-1jiuA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		5 / 12 GLY A   9
SER A  82
TYR A 121
LEU A 126
LEU A  42
 None
 1.36A 4xldA-1jiuA:
undetectable		 4xldA-1jiuA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		3 / 3 ASN A  70
SER A  68
ARG A 102
 None
 0.94A 5b2qA-1jiuA:
0.0		 5b2qA-1jiuA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		3 / 3 LEU A 306
THR A 273
ASN A 247
 None
 0.70A 6baaE-1jiuA:
undetectable		 6baaE-1jiuA:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		3 / 3 LEU A 306
THR A 273
ASN A 247
 None
 0.69A 6baaF-1jiuA:
undetectable		 6baaF-1jiuA:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		3 / 3 LEU A 306
THR A 273
ASN A 247
 None
 0.70A 6baaG-1jiuA:
0.0		 6baaG-1jiuA:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1jiu DNA
BETA-GLUCOSYLTRANSFE
RASE
(Escherichia
virus
T4) 		3 / 3 LEU A 306
THR A 273
ASN A 247
 None
 0.70A 6baaH-1jiuA:
0.0		 6baaH-1jiuA:
11.80