SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jj4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1jj4 REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
7) 		5 / 10 ARG A 314
THR A 334
GLY A 361
HIS A 291
THR A 287
 None
 1.45A 1c9sG-1jj4A:
undetectable
1c9sH-1jj4A:
undetectable		 1c9sG-1jj4A:
18.60
1c9sH-1jj4A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BL9_A_CP6A1240_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1jj4 REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
7) 		5 / 12 ILE A 358
LEU A 299
SER A 317
ILE A 316
ILE A 290
 None
 1.06A 2bl9A-1jj4A:
undetectable		 2bl9A-1jj4A:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQ8_A_TOPA2001_1
(DIHYDROFOLATE
REDUCTASE)		 1jj4 REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
7) 		5 / 9 ILE A 358
LEU A 299
SER A 317
ILE A 316
ILE A 290
 None
 1.20A 3tq8A-1jj4A:
undetectable		 3tq8A-1jj4A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 1jj4 REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
7) 		3 / 3 TRP A 322
TRP A 320
THR A 334
 None
 1.39A 4bboB-1jj4A:
undetectable		 4bboB-1jj4A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 1jj4 REGULATORY PROTEIN
E2
(Alphapapillomavi
rus
7) 		3 / 3 ARG A 303
ILE A 316
SER A 317
 None
 0.88A 5zw2A-1jj4A:
undetectable		 5zw2A-1jj4A:
12.17