SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jj7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 1jj7 PEPTIDE TRANSPORTER
TAP1
(Homo
sapiens) 		3 / 3 PHE A 624
LEU A 673
SER A 619
 None
 0.75A 1e7aA-1jj7A:
undetectable		 1e7aA-1jj7A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HBP_A_RTLA184_0
(RETINOL BINDING
PROTEIN)		 1jj7 PEPTIDE TRANSPORTER
TAP1
(Homo
sapiens) 		5 / 11 LEU A 673
ALA A 548
VAL A 681
LEU A 653
GLN A 649
 None
 1.06A 1hbpA-1jj7A:
undetectable		 1hbpA-1jj7A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 1jj7 PEPTIDE TRANSPORTER
TAP1
(Homo
sapiens) 		5 / 12 LEU A 697
GLY A 724
GLY A 723
THR A 534
LEU A 536
 None
 1.02A 1liiA-1jj7A:
undetectable		 1liiA-1jj7A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 1jj7 PEPTIDE TRANSPORTER
TAP1
(Homo
sapiens) 		5 / 12 GLY A 585
LEU A 653
ASP A 668
LEU A 697
VAL A 696
 None
 0.95A 2yqzB-1jj7A:
undetectable		 2yqzB-1jj7A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 1jj7 PEPTIDE TRANSPORTER
TAP1
(Homo
sapiens) 		4 / 4 LEU A 673
ALA A 669
VAL A 584
PRO A 588
 None
 1.10A 3gv1B-1jj7A:
0.0		 3gv1B-1jj7A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1jj7 PEPTIDE TRANSPORTER
TAP1
(Homo
sapiens) 		4 / 7 ALA A 621
ARG A 648
ALA A 652
ARG A 655
 None
 0.95A 3twpA-1jj7A:
undetectable		 3twpA-1jj7A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V1N_A_BEZA288_0
(2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE)		 1jj7 PEPTIDE TRANSPORTER
TAP1
(Homo
sapiens) 		5 / 8 GLY A 717
GLY A 718
SER A 542
GLY A 538
LEU A 536
 None
None
ADP  A 752 (-3.4A)
None
None
 1.41A 3v1nA-1jj7A:
undetectable		 3v1nA-1jj7A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUB_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1jj7 PEPTIDE TRANSPORTER
TAP1
(Homo
sapiens) 		3 / 3 TYR A 601
ARG A 659
HIS A 578
 None
 0.88A 4fubA-1jj7A:
0.0		 4fubA-1jj7A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1jj7 PEPTIDE TRANSPORTER
TAP1
(Homo
sapiens) 		5 / 12 ILE A 720
GLY A 538
ILE A 699
ASP A 668
SER A 542
 None
None
None
None
ADP  A 752 (-3.4A)
 1.10A 4iv0B-1jj7A:
undetectable		 4iv0B-1jj7A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 1jj7 PEPTIDE TRANSPORTER
TAP1
(Homo
sapiens) 		4 / 4 LEU A 703
ILE A 712
HIS A 726
VAL A 706
 None
 1.11A 4xyzA-1jj7A:
0.0		 4xyzA-1jj7A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1jj7 PEPTIDE TRANSPORTER
TAP1
(Homo
sapiens) 		4 / 4 ALA A 652
PRO A 661
LEU A 577
HIS A 578
 None
 1.22A 5eskA-1jj7A:
0.0		 5eskA-1jj7A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 1jj7 PEPTIDE TRANSPORTER
TAP1
(Homo
sapiens) 		5 / 12 GLY A 646
VAL A 681
VAL A 651
ALA A 652
LEU A 653
 None
 1.11A 5kocA-1jj7A:
undetectable		 5kocA-1jj7A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_1
(WTFP-TAG,GP41)		 1jj7 PEPTIDE TRANSPORTER
TAP1
(Homo
sapiens) 		5 / 12 ALA A 621
GLY A 620
SER A 677
GLN A 683
GLU A 687
 None
 1.21A 5nwuA-1jj7A:
0.0		 5nwuA-1jj7A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)		 1jj7 PEPTIDE TRANSPORTER
TAP1
(Homo
sapiens) 		4 / 8 ARG A 515
SER A 509
THR A 558
GLY A 718
 ADP  A 752 (-4.0A)
None
None
None
 0.95A 5v0vA-1jj7A:
undetectable		 5v0vA-1jj7A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1jj7 PEPTIDE TRANSPORTER
TAP1
(Homo
sapiens) 		4 / 8 VAL A 508
GLN A 522
GLY A 718
LEU A 715
 None
 0.79A 5w3jB-1jj7A:
undetectable		 5w3jB-1jj7A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CGD_A_AKNA600_1
(BIFUNCTIONAL AAC/APH)		 1jj7 PEPTIDE TRANSPORTER
TAP1
(Homo
sapiens) 		5 / 10 GLY A 538
ASP A 668
ASP A 667
VAL A 681
GLU A 682
 None
None
MG  A 902 ( 4.1A)
None
None
 1.45A 6cgdA-1jj7A:
undetectable		 6cgdA-1jj7A:
13.87