SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jjf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		5 / 10 GLY A  89
SER A 172
MET A 173
LEU A 232
HIS A 260
 None
None
PT  A 288 (-2.7A)
None
None
 0.90A 1a8uA-1jjfA:
14.3		 1a8uA-1jjfA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		5 / 10 GLY A  89
SER A 172
MET A 173
LEU A 232
HIS A 260
 None
None
PT  A 288 (-2.7A)
None
None
 0.89A 1a8uB-1jjfA:
14.1		 1a8uB-1jjfA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		4 / 8 ILE A 248
LEU A 222
PHE A 179
GLY A 236
 None
 0.90A 1os6A-1jjfA:
undetectable		 1os6A-1jjfA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		4 / 8 ASP A 230
TYR A 252
LEU A 254
GLY A 258
 None
 0.89A 1rmtC-1jjfA:
undetectable		 1rmtC-1jjfA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_1
(PROTEASE RETROPEPSIN)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		5 / 10 GLY A 170
ALA A 169
GLY A 182
ILE A 181
VAL A  83
 None
 0.94A 1t3rA-1jjfA:
undetectable		 1t3rA-1jjfA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B9E_A_SAMA1201_0
(NOL1/NOP2/SUN DOMAIN
FAMILY, MEMBER 5
ISOFORM 2)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		5 / 12 CYH A 226
PRO A 267
GLY A 268
ASN A 271
ASP A 261
 None
 1.42A 2b9eA-1jjfA:
undetectable		 2b9eA-1jjfA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2003_1
(SERUM ALBUMIN)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		5 / 10 LEU A 269
LEU A  84
LEU A 120
ILE A 117
ALA A 276
 None
 1.11A 2bxeB-1jjfA:
undetectable		 2bxeB-1jjfA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMY_B_SAMB328_0
(PROTEIN
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI))		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		5 / 12 PHE A 141
GLY A 137
GLY A 131
ILE A 181
LEU A  87
 None
 1.09A 2hmyB-1jjfA:
2.4		 2hmyB-1jjfA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		4 / 8 ILE A 192
PHE A 141
GLY A 176
GLY A 175
 None
 0.89A 2qx4A-1jjfA:
undetectable
2qx4B-1jjfA:
undetectable		 2qx4A-1jjfA:
19.16
2qx4B-1jjfA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		4 / 6 LEU A 145
LEU A 149
ILE A 168
ARG A 166
 None
 0.95A 2rlfC-1jjfA:
undetectable
2rlfD-1jjfA:
0.0		 2rlfC-1jjfA:
10.27
2rlfD-1jjfA:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		3 / 3 LEU A 273
TRP A 265
TYR A  39
 None
 1.00A 3aicA-1jjfA:
undetectable		 3aicA-1jjfA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		3 / 3 LEU A 273
TRP A 265
TYR A  39
 None
 0.99A 3aicB-1jjfA:
undetectable		 3aicB-1jjfA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		3 / 3 LEU A 273
TRP A 265
TYR A  39
 None
 0.99A 3aicE-1jjfA:
undetectable		 3aicE-1jjfA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		3 / 3 LEU A 273
TRP A 265
TYR A  39
 None
 0.98A 3aicF-1jjfA:
undetectable		 3aicF-1jjfA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		3 / 3 LEU A 273
TRP A 265
TYR A  39
 None
 0.97A 3aicG-1jjfA:
undetectable		 3aicG-1jjfA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		3 / 3 LEU A 273
TRP A 265
TYR A  39
 None
 1.01A 3aicH-1jjfA:
undetectable		 3aicH-1jjfA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_0
(REPRESSOR PROTEIN
MPHR(A))		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		5 / 12 THR A 142
LEU A 145
ILE A 168
VAL A 239
ILE A 248
 None
 1.03A 3frqB-1jjfA:
undetectable		 3frqB-1jjfA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		4 / 6 ILE A 248
LEU A 222
PHE A 179
GLY A 236
 None
 0.83A 3sj1X-1jjfA:
0.0		 3sj1X-1jjfA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		4 / 5 ILE A 168
TYR A 202
GLY A 175
PRO A 194
 None
 1.03A 3uboB-1jjfA:
3.2		 3uboB-1jjfA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		3 / 3 GLY A 182
THR A 184
ASN A 180
 None
 0.64A 3v4tD-1jjfA:
undetectable		 3v4tD-1jjfA:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		4 / 7 ILE A 248
LEU A 222
PHE A 179
GLY A 236
 None
 0.96A 4hajA-1jjfA:
undetectable		 4hajA-1jjfA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		4 / 7 ILE A 248
LEU A 222
PHE A 179
GLY A 236
 None
 0.84A 4hbfA-1jjfA:
0.0		 4hbfA-1jjfA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		4 / 7 ILE A 248
LEU A 222
PHE A 179
GLY A 236
 None
 0.87A 4hc3A-1jjfA:
undetectable		 4hc3A-1jjfA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		5 / 12 GLY A 176
GLY A 174
ILE A 195
SER A 196
ALA A 197
 None
 1.07A 4qtuD-1jjfA:
undetectable		 4qtuD-1jjfA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		3 / 3 LYS A 266
ARG A  43
VAL A  42
 None
 1.02A 4x3uA-1jjfA:
0.0
4x3uB-1jjfA:
0.0		 4x3uA-1jjfA:
14.88
4x3uB-1jjfA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		5 / 11 GLY A 268
ALA A 108
ILE A 122
LEU A  84
LEU A 281
 None
 1.15A 4xumB-1jjfA:
0.0		 4xumB-1jjfA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		4 / 7 ILE A 195
PHE A 223
VAL A 264
ILE A 255
 None
 0.98A 4zzbC-1jjfA:
0.0
4zzbD-1jjfA:
0.0		 4zzbC-1jjfA:
25.66
4zzbD-1jjfA:
25.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_E_SAME301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		5 / 12 PRO A 199
GLY A 174
GLY A 176
ALA A 169
LEU A 171
 None
 1.11A 5c0oE-1jjfA:
undetectable		 5c0oE-1jjfA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		5 / 12 GLY A 174
GLY A 182
GLY A 170
LYS A 188
ASP A 187
 None
 0.99A 5wz1A-1jjfA:
undetectable		 5wz1A-1jjfA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		5 / 12 GLY A 174
GLY A 182
GLY A 170
LYS A 188
ASP A 187
 None
 1.06A 5wz1F-1jjfA:
undetectable		 5wz1F-1jjfA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		5 / 12 GLY A 174
GLY A 182
GLY A 170
LYS A 188
ASP A 187
 None
 0.99A 5wz1G-1jjfA:
undetectable		 5wz1G-1jjfA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_I_PACI1_0
(SERINE PROTEASE NS3
SERINE PROTEASE
SUBUNIT NS2B
PEPTIDE
PAC-DLY-DLY-DAR)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		3 / 3 VAL A  51
TYR A  70
GLU A  99
 None
 0.75A 5zmqD-1jjfA:
0.0
5zmqE-1jjfA:
undetectable		 5zmqD-1jjfA:
24.73
5zmqE-1jjfA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA806_0
(GEPHYRIN)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		4 / 4 MET A 173
GLY A  89
HIS A  88
GLY A 174
 PT  A 288 (-2.7A)
None
None
None
 1.46A 6fgdA-1jjfA:
2.1		 6fgdA-1jjfA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		4 / 6 GLU A  99
ARG A  68
PHE A  98
VAL A 106
 None
 1.39A 6fgdA-1jjfA:
undetectable		 6fgdA-1jjfA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_1
(TYROSINE-PROTEIN
KINASE ABL1)		 1jjf ENDO-1,4-BETA-XYLANA
SE Z
(Ruminiclostridiu
m
thermocellum) 		4 / 6 LEU A  84
VAL A  42
PHE A 272
GLY A 170
 None
 1.01A 6hd4B-1jjfA:
undetectable		 6hd4B-1jjfA:
14.57