SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jke'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_1
(PCZA361.24)		 1jke D-TYR-TRNATYR
DEACYLASE
(Escherichia
coli) 		3 / 3 ARG A  48
GLU A  34
ASP A  84
 None
 0.65A 3g2oA-1jkeA:
undetectable		 3g2oA-1jkeA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1jke D-TYR-TRNATYR
DEACYLASE
(Escherichia
coli) 		5 / 8 VAL A  29
LEU A  31
VAL A  49
ARG A  48
LEU A  45
 None
 1.29A 3kp6A-1jkeA:
undetectable
3kp6B-1jkeA:
undetectable		 3kp6A-1jkeA:
21.08
3kp6B-1jkeA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 1jke D-TYR-TRNATYR
DEACYLASE
(Escherichia
coli) 		4 / 4 LEU A  45
LEU A  31
GLY A  32
GLU A  34
 None
 1.14A 5hhjA-1jkeA:
0.0		 5hhjA-1jkeA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 1jke D-TYR-TRNATYR
DEACYLASE
(Escherichia
coli) 		5 / 12 ALA A  11
VAL A 110
GLN A 116
LEU A  50
VAL A  66
 None
 1.20A 5tudD-1jkeA:
undetectable		 5tudD-1jkeA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_0
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 1jke D-TYR-TRNATYR
DEACYLASE
(Escherichia
coli) 		5 / 12 GLY A 123
SER A  12
LEU A  74
VAL A  76
LEU A  28
 None
 1.26A 5ubbA-1jkeA:
undetectable		 5ubbA-1jkeA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1jke D-TYR-TRNATYR
DEACYLASE
(Escherichia
coli) 		5 / 8 GLY A  51
LEU A  50
LEU A  28
VAL A  73
LEU A  45
 None
 1.26A 5vkqB-1jkeA:
undetectable
5vkqC-1jkeA:
undetectable		 5vkqB-1jkeA:
6.90
5vkqC-1jkeA:
6.90