SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jkm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A27_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 SER A 235
GLY A 237
ASN A 262
TYR A 238
GLU A 243
 None
 1.18A 1a27A-1jkmA:
2.9		 1a27A-1jkmA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		4 / 8 GLY A 127
SER A 202
PHE A 259
HIS A 338
 None
 1.01A 1ax9A-1jkmA:
19.3		 1ax9A-1jkmA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 GLY A 126
GLY A 127
GLY A 128
SER A 202
HIS A 338
 None
 0.37A 1dx6A-1jkmA:
20.2		 1dx6A-1jkmA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 GLY A 126
GLY A 127
SER A 202
PHE A 259
HIS A 338
 None
 0.58A 1dx6A-1jkmA:
20.2		 1dx6A-1jkmA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 LEU A 268
TYR A 272
GLY A 126
SER A 202
LEU A 310
 None
 1.12A 1fe2A-1jkmA:
0.0		 1fe2A-1jkmA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 PHE A 344
VAL A 337
ILE A 260
TYR A  75
LEU A  37
 None
 1.17A 1fm4A-1jkmA:
undetectable		 1fm4A-1jkmA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		4 / 8 ALA A 180
GLY A 173
ALA A 179
THR A 211
 None
 0.69A 1gtnI-1jkmA:
undetectable
1gtnJ-1jkmA:
undetectable		 1gtnI-1jkmA:
12.43
1gtnJ-1jkmA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 LEU A 268
TYR A 272
GLY A 126
SER A 202
LEU A 310
 None
 1.07A 1igxA-1jkmA:
0.0		 1igxA-1jkmA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_A_THAA1_1
(LIVER
CARBOXYLESTERASE I)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		6 / 11 LEU A 132
GLY A 127
GLY A 128
SER A 202
LEU A 268
HIS A 338
 None
 1.35A 1mx1A-1jkmA:
19.2		 1mx1A-1jkmA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_1
(LIVER
CARBOXYLESTERASE I)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 GLY A 127
GLY A 128
SER A 202
ILE A 260
HIS A 338
 None
 0.60A 1mx1D-1jkmA:
18.6		 1mx1D-1jkmA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 GLY A 127
GLY A 128
SER A 202
LEU A 268
HIS A 338
 None
 0.90A 1mx1F-1jkmA:
18.3		 1mx1F-1jkmA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 GLY A 126
GLY A 127
GLY A 128
SER A 202
HIS A 338
 None
 0.37A 1qtiA-1jkmA:
3.9		 1qtiA-1jkmA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 TYR A 233
GLY A 126
ILE A 131
HIS A 338
PHE A 259
 None
 1.15A 1ve3B-1jkmA:
2.6		 1ve3B-1jkmA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 GLY A 126
GLY A 127
GLY A 128
SER A 202
HIS A 338
 None
 0.37A 1w6rA-1jkmA:
20.2		 1w6rA-1jkmA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 GLY A 126
GLY A 127
SER A 202
PHE A 259
HIS A 338
 None
 0.83A 1w6rA-1jkmA:
20.2		 1w6rA-1jkmA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 11 GLY A 127
GLY A 128
SER A 202
PHE A 259
HIS A 338
 None
 0.61A 1w76A-1jkmA:
19.0		 1w76A-1jkmA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		6 / 8 GLY A 126
GLY A 127
GLY A 128
SER A 202
ILE A 260
HIS A 338
 None
 0.53A 1yajC-1jkmA:
18.4		 1yajC-1jkmA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 8 GLY A 126
GLY A 127
LEU A 268
ILE A 260
HIS A 338
 None
 1.07A 1yajC-1jkmA:
18.4		 1yajC-1jkmA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 8 GLY A 128
GLY A 203
GLY A 204
ILE A 231
HIS A 338
 None
 0.99A 1yajC-1jkmA:
18.4		 1yajC-1jkmA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		6 / 6 LEU A 132
GLY A 127
SER A 202
LEU A 268
ILE A 260
HIS A 338
 None
 1.35A 1yajF-1jkmA:
18.4		 1yajF-1jkmA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		4 / 4 GLY A 127
SER A 202
ILE A 260
HIS A 338
 None
 0.66A 1yajJ-1jkmA:
15.8		 1yajJ-1jkmA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		4 / 4 GLY A 128
SER A 202
ILE A 260
HIS A 338
 None
 1.02A 1yajJ-1jkmA:
15.8		 1yajJ-1jkmA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		3 / 3 PRO A  27
THR A  25
PRO A  23
 None
 0.78A 2d55C-1jkmA:
undetectable		 2d55C-1jkmA:
7.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_1
(PROTEASE)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		6 / 12 LEU A 178
GLY A 173
ASP A 157
VAL A 156
GLY A 204
VAL A 181
 None
 1.44A 2ieoA-1jkmA:
undetectable		 2ieoA-1jkmA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		4 / 8 PHE A 344
TRP A 347
ALA A  38
LEU A  37
 None
 0.94A 2o01A-1jkmA:
undetectable		 2o01A-1jkmA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		4 / 7 PHE A  71
PHE A 259
ILE A  78
GLY A 126
 None
 0.98A 2v0mC-1jkmA:
0.0		 2v0mC-1jkmA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 ARG A 110
GLY A 150
PRO A 111
ASP A 358
VAL A 359
 None
 1.29A 2zznA-1jkmA:
1.4		 2zznA-1jkmA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		4 / 7 SER A 194
ALA A 364
ALA A 363
ALA A 367
 None
 0.60A 3a2qA-1jkmA:
0.1		 3a2qA-1jkmA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_B_SAMB600_0
(PCZA361.24)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 ALA A 363
GLY A 361
ASP A 225
GLY A 150
SER A 151
 None
 1.09A 3g2oB-1jkmA:
undetectable		 3g2oB-1jkmA:
27.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 ILE A 315
GLY A 314
ALA A 303
VAL A 304
ASN A 305
 None
 0.91A 3jb3A-1jkmA:
1.8		 3jb3A-1jkmA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 HIS A 338
ASP A 308
VAL A 138
GLY A 126
SER A 202
 None
 1.01A 3keeB-1jkmA:
undetectable		 3keeB-1jkmA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_A_BEZA999_0
(CHOLINESTERASE)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		4 / 7 GLY A 127
GLY A 128
SER A 202
HIS A 338
 None
 0.36A 3o9mA-1jkmA:
11.1		 3o9mA-1jkmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		4 / 6 GLY A 127
GLY A 128
SER A 202
HIS A 338
 None
 0.42A 3o9mB-1jkmA:
8.1		 3o9mB-1jkmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 HIS A 338
ASP A 308
ARG A 331
GLY A 126
SER A 202
 None
 0.86A 3sueB-1jkmA:
undetectable		 3sueB-1jkmA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 HIS A 338
ASP A 308
ARG A 331
GLY A 126
SER A 202
 None
 0.91A 3sueD-1jkmA:
undetectable		 3sueD-1jkmA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 HIS A 338
ASP A 308
ARG A 331
GLY A 203
SER A 202
 None
 1.23A 3sueD-1jkmA:
undetectable		 3sueD-1jkmA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 HIS A 338
ASP A 308
ARG A 331
GLY A 126
SER A 202
 None
 0.78A 3sufA-1jkmA:
undetectable		 3sufA-1jkmA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		4 / 8 PHE A  29
THR A  25
PRO A  27
GLY A  14
 None
 0.95A 3tzfB-1jkmA:
3.0		 3tzfB-1jkmA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 LEU A 321
PHE A 300
LEU A 294
SER A 290
PRO A 282
 None
 1.35A 3w1wA-1jkmA:
4.2		 3w1wA-1jkmA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_C_IMNC701_1
(CYCLOOXYGENASE-2)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 LEU A 352
TRP A 142
GLY A 339
ALA A 340
LEU A 336
 None
 1.12A 4coxC-1jkmA:
undetectable		 4coxC-1jkmA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 GLY A 126
GLY A 127
GLY A 128
SER A 202
HIS A 338
 None
 0.32A 4ey6A-1jkmA:
20.7		 4ey6A-1jkmA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 GLY A 126
GLY A 127
GLY A 128
SER A 202
HIS A 338
 None
 0.35A 4ey6B-1jkmA:
17.2		 4ey6B-1jkmA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		3 / 3 LEU A  82
PRO A  83
ARG A 357
 None
 0.75A 4klrB-1jkmA:
4.3		 4klrB-1jkmA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_1
(PROTEASE)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 8 ALA A 223
ASP A 222
GLY A 195
VAL A 227
ILE A 224
 None
 1.42A 4ll3A-1jkmA:
undetectable		 4ll3A-1jkmA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 9 VAL A 269
ALA A 266
TYR A 238
GLY A 127
GLY A 264
 None
 1.34A 4mmeA-1jkmA:
undetectable		 4mmeA-1jkmA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 9 VAL A 269
ALA A 266
TYR A 238
GLY A 127
GLY A 264
 None
 1.35A 4mmeB-1jkmA:
0.0		 4mmeB-1jkmA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 9 VAL A 269
ALA A 266
TYR A 238
GLY A 127
GLY A 264
 None
 1.33A 4mmfA-1jkmA:
0.0		 4mmfA-1jkmA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 9 VAL A 269
ALA A 266
TYR A 238
GLY A 127
GLY A 264
 None
 1.35A 4mmfB-1jkmA:
0.0		 4mmfB-1jkmA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 ARG A 368
ALA A 367
SER A 194
GLY A 120
GLY A 361
 None
 1.20A 4r29C-1jkmA:
0.0		 4r29C-1jkmA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_B_DM2B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 11 VAL A 138
PHE A 158
GLY A 200
GLY A 205
ILE A 231
 None
 1.13A 4zvmA-1jkmA:
3.2
4zvmB-1jkmA:
3.7		 4zvmA-1jkmA:
20.17
4zvmB-1jkmA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		3 / 3 HIS A 187
GLU A 186
TRP A 183
 None
 0.94A 5odiD-1jkmA:
2.2		 5odiD-1jkmA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		3 / 3 HIS A 187
GLU A 186
TRP A 183
 None
 0.95A 5odqD-1jkmA:
2.3		 5odqD-1jkmA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		3 / 3 HIS A 187
GLU A 186
TRP A 183
 None
 0.88A 5odrD-1jkmA:
2.1		 5odrD-1jkmA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_1
(RIFAMPIN
MONOOXYGENASE)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 PHE A  40
GLY A 339
VAL A 337
PHE A  29
GLY A  41
 None
 1.06A 6brdB-1jkmA:
0.8		 6brdB-1jkmA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 12 HIS A 338
ASP A 308
ARG A 331
GLY A 126
SER A 202
 None
 0.83A 6c2mC-1jkmA:
undetectable		 6c2mC-1jkmA:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		4 / 4 HIS A 167
VAL A  60
LEU A  57
ALA A 271
 None
 0.96A 6d8pB-1jkmA:
2.6		 6d8pB-1jkmA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		4 / 4 HIS A 167
VAL A  64
LEU A  61
ALA A 161
 None
 1.27A 6d8pB-1jkmA:
2.6		 6d8pB-1jkmA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA715_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		5 / 6 GLY A  98
ASN A 102
ASP A 100
SER A 172
ARG A 159
 None
 1.44A 6dwdA-1jkmA:
0.0
6dwdC-1jkmA:
0.0		 6dwdA-1jkmA:
20.36
6dwdC-1jkmA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		3 / 3 GLN A  72
TYR A  75
ASN A 136
 None
 0.97A 6dwdC-1jkmA:
0.0		 6dwdC-1jkmA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_Q_PCFQ202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1jkm BREFELDIN A ESTERASE
(Bacillus
subtilis) 		4 / 6 TYR A 228
ALA A 330
ARG A 331
ASP A 341
 None
 0.96A 6hu9m-1jkmA:
0.0
6hu9q-1jkmA:
0.0		 6hu9m-1jkmA:
22.81
6hu9q-1jkmA:
16.57