SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jl5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRL_B_DOLB301_1
(STREPTOGRAMIN A
ACETYLTRANSFERASE)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		5 / 12 LEU A1165
PRO A1147
LEU A1129
ASN A1205
ASP A1161
 None
 1.29A 1mrlB-1jl5A:
1.8
1mrlC-1jl5A:
2.3		 1mrlB-1jl5A:
17.56
1mrlC-1jl5A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_B_DESB128_1
(TRANSTHYRETIN)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 5 LEU A1081
ALA A1098
LEU A1083
SER A1085
 None
 1.02A 1tt6B-1jl5A:
0.0		 1tt6B-1jl5A:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 6 LEU A1081
ALA A1098
LEU A1083
SER A1085
 None
 1.06A 1tz8C-1jl5A:
undetectable
1tz8D-1jl5A:
undetectable		 1tz8C-1jl5A:
12.64
1tz8D-1jl5A:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_A_NCAA506_0
(NAD-DEPENDENT
DEACETYLASE 2)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 6 ALA A1304
SER A1285
ASN A1303
ASP A1283
 None
 0.97A 1yc2A-1jl5A:
undetectable		 1yc2A-1jl5A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 7 SER A1305
SER A1306
SER A1285
ASN A1303
 None
 1.11A 2cmlA-1jl5A:
undetectable		 2cmlA-1jl5A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 8 SER A1305
SER A1306
SER A1285
ASN A1303
 None
 1.04A 2cmlB-1jl5A:
undetectable		 2cmlB-1jl5A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 8 SER A1305
SER A1306
SER A1285
ASN A1303
 None
 1.08A 2cmlC-1jl5A:
undetectable		 2cmlC-1jl5A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA501_0
(FERROCHELATASE)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		5 / 11 LEU A1175
LEU A1197
LEU A1217
ILE A1158
THR A1241
 None
 1.29A 2qd3A-1jl5A:
undetectable		 2qd3A-1jl5A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_A_GLYA74_0
(NONSTRUCTURAL
PROTEIN 1)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 4 LYS A1036
LEU A1069
ARG A1071
GLN A1072
 None
 1.35A 2z0aA-1jl5A:
0.2		 2z0aA-1jl5A:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		3 / 3 HIS A1092
GLU A1094
HIS A1074
 None
 0.77A 3ba0A-1jl5A:
undetectable		 3ba0A-1jl5A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 5 PRO A1296
SER A1278
LEU A1319
SER A1318
 None
 1.27A 3ijxH-1jl5A:
0.0		 3ijxH-1jl5A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 5 PRO A1296
SER A1278
LEU A1319
SER A1318
 None
 1.19A 3iluH-1jl5A:
0.0		 3iluH-1jl5A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		3 / 3 TYR A1268
LEU A1207
LYS A1209
 None
 0.76A 3sueD-1jl5A:
0.0		 3sueD-1jl5A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_1
(HIV-1 PROTEASE)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 7 ALA A1180
ASP A1161
ASP A1159
ILE A1220
 None
 0.72A 3t3cA-1jl5A:
undetectable		 3t3cA-1jl5A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		3 / 3 ASN A1303
LEU A1315
PHE A1289
 None
 0.80A 4dajB-1jl5A:
undetectable		 4dajB-1jl5A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_D_SAMD800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		5 / 10 ILE A1343
GLU A1286
ASN A1263
ASN A1323
TYR A1301
 None
CA  A2001 ( 4.3A)
None
None
None
 1.43A 4e47D-1jl5A:
0.0		 4e47D-1jl5A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		5 / 12 LEU A1175
LEU A1197
LEU A1217
ILE A1158
THR A1241
 None
 1.28A 4f4dA-1jl5A:
0.0		 4f4dA-1jl5A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J83_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		5 / 11 ILE A1343
GLU A1286
ASN A1263
ASN A1323
TYR A1301
 None
CA  A2001 ( 4.3A)
None
None
None
 1.38A 4j83A-1jl5A:
0.0		 4j83A-1jl5A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_D_SAMD401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		5 / 11 ILE A1343
GLU A1286
ASN A1263
ASN A1323
TYR A1301
 None
CA  A2001 ( 4.3A)
None
None
None
 1.44A 4jdsD-1jl5A:
undetectable		 4jdsD-1jl5A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		5 / 11 ILE A1343
GLU A1286
ASN A1263
ASN A1323
TYR A1301
 None
CA  A2001 ( 4.3A)
None
None
None
 1.40A 4jlgB-1jl5A:
0.0		 4jlgB-1jl5A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTQ_A_FLPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		5 / 10 VAL A1138
VAL A1160
ILE A1158
LEU A1113
LEU A1133
 None
 1.48A 4jtqA-1jl5A:
undetectable		 4jtqA-1jl5A:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 8 VAL A1138
LEU A1123
LEU A1143
ASP A1128
 None
 0.76A 4lzrA-1jl5A:
undetectable		 4lzrA-1jl5A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 8 VAL A1264
LEU A1249
LEU A1269
ASP A1254
 None
 0.85A 4lzrA-1jl5A:
undetectable		 4lzrA-1jl5A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 5 LEU A1109
SER A1115
LEU A1093
LEU A1106
 None
 1.19A 4n09B-1jl5A:
undetectable		 4n09B-1jl5A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 5 LEU A1136
SER A1139
LEU A1117
LEU A1126
 None
 1.24A 4n09B-1jl5A:
undetectable		 4n09B-1jl5A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 5 LEU A1213
SER A1219
LEU A1197
LEU A1210
 None
 1.27A 4n09B-1jl5A:
undetectable		 4n09B-1jl5A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_2
(ADENOSINE KINASE)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 5 ASN A1121
LEU A1123
SER A1139
LEU A1136
 None
 1.07A 4n09C-1jl5A:
undetectable		 4n09C-1jl5A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_2
(ADENOSINE KINASE)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 5 ASN A1267
LEU A1269
SER A1285
LEU A1282
 None
 1.09A 4n09C-1jl5A:
undetectable		 4n09C-1jl5A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 5 LEU A1109
SER A1115
LEU A1093
LEU A1106
 None
 1.19A 4n09D-1jl5A:
undetectable		 4n09D-1jl5A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 5 LEU A1136
SER A1139
LEU A1117
LEU A1126
 None
 1.25A 4n09D-1jl5A:
undetectable		 4n09D-1jl5A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 5 LEU A1213
SER A1219
LEU A1197
LEU A1210
 None
 1.27A 4n09D-1jl5A:
undetectable		 4n09D-1jl5A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 7 ASN A1163
LEU A1149
LEU A1116
ILE A1178
 None
 1.04A 4okwA-1jl5A:
0.0		 4okwA-1jl5A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA603_1
(SERUM ALBUMIN)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		5 / 10 LEU A1133
LEU A1129
VAL A1160
LEU A1165
LEU A1168
 None
 1.13A 4po0A-1jl5A:
1.7		 4po0A-1jl5A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA603_1
(SERUM ALBUMIN)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		5 / 10 LEU A1312
LEU A1315
VAL A1352
LEU A1355
LEU A1362
 None
 1.11A 4po0A-1jl5A:
1.7		 4po0A-1jl5A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA603_1
(SERUM ALBUMIN)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		5 / 10 LEU A1329
LEU A1312
VAL A1284
LEU A1282
LEU A1272
 None
 1.18A 4po0A-1jl5A:
1.7		 4po0A-1jl5A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 6 LEU A1081
ALA A1098
LEU A1083
SER A1085
 None
 1.04A 4pwjA-1jl5A:
undetectable		 4pwjA-1jl5A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA601_1
(SERUM ALBUMIN)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		5 / 11 LEU A1076
LEU A1106
GLY A1137
SER A1115
LEU A1113
 None
 1.04A 4zbqA-1jl5A:
undetectable		 4zbqA-1jl5A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 6 LEU A1081
ALA A1098
LEU A1083
SER A1085
 None
 1.06A 5bojA-1jl5A:
undetectable		 5bojA-1jl5A:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 4 LEU A1136
ILE A1158
PRO A1169
LEU A1165
 None
 1.04A 5eb3A-1jl5A:
undetectable		 5eb3A-1jl5A:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_B_1FLB1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		5 / 9 LEU A1168
LEU A1191
ILE A1200
PRO A1231
LEU A1213
 None
 1.50A 5g48B-1jl5A:
0.0		 5g48B-1jl5A:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 7 VAL A1118
LEU A1123
ALA A1098
LEU A1113
 None
 0.60A 5jq7A-1jl5A:
0.0		 5jq7A-1jl5A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 7 VAL A1264
LEU A1269
ALA A1244
LEU A1259
 None
 0.66A 5jq7A-1jl5A:
0.0		 5jq7A-1jl5A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 7 VAL A1324
LEU A1329
ALA A1304
LEU A1319
 None
 0.57A 5jq7A-1jl5A:
0.0		 5jq7A-1jl5A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 7 VAL A1364
LEU A1369
ALA A1344
LEU A1359
 None
 0.59A 5jq7A-1jl5A:
0.0		 5jq7A-1jl5A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 4 ASN A1121
LEU A1123
SER A1139
LEU A1136
 None
 1.05A 5kb5A-1jl5A:
undetectable		 5kb5A-1jl5A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 4 ASN A1267
LEU A1269
SER A1285
LEU A1282
 None
 1.08A 5kb5A-1jl5A:
undetectable		 5kb5A-1jl5A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_2
(PROTEASE E35D-DRV)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 7 ALA A1180
ASP A1161
ASP A1159
ILE A1220
 None
 0.66A 5kqyB-1jl5A:
undetectable		 5kqyB-1jl5A:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 6 LEU A1081
ALA A1098
LEU A1083
SER A1085
 None
 1.04A 5l4iA-1jl5A:
undetectable		 5l4iA-1jl5A:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 6 ASP A1203
ASP A1119
ASN A1141
ASN A1182
 None
None
None
CA  A2003 (-3.6A)
 1.25A 5l6eA-1jl5A:
undetectable		 5l6eA-1jl5A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		5 / 12 LEU A1275
PRO A1316
SER A1318
TYR A1301
LEU A1312
 None
 1.11A 5ljeA-1jl5A:
undetectable		 5ljeA-1jl5A:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		5 / 10 PRO A1130
LEU A1149
ILE A1178
ALA A1180
VAL A1138
 None
 1.37A 5m0oA-1jl5A:
undetectable		 5m0oA-1jl5A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		5 / 12 LEU A1081
LEU A1078
ASN A1101
SER A1095
LEU A1093
 None
 1.15A 5mwyA-1jl5A:
undetectable		 5mwyA-1jl5A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		3 / 3 LEU A1096
ASN A1122
LEU A1126
 None
 0.60A 6exiA-1jl5A:
undetectable		 6exiA-1jl5A:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		3 / 3 LEU A1332
ASN A1303
LEU A1295
 None
 0.62A 6exiA-1jl5A:
undetectable		 6exiA-1jl5A:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		5 / 10 VAL A1118
LEU A1123
LEU A1143
LEU A1109
LEU A1106
 None
 0.93A 6f5uA-1jl5A:
0.2
6f5uB-1jl5A:
undetectable		 6f5uA-1jl5A:
10.47
6f5uB-1jl5A:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		5 / 10 VAL A1138
LEU A1143
LEU A1165
LEU A1129
LEU A1126
 None
 0.83A 6f5uA-1jl5A:
0.2
6f5uB-1jl5A:
undetectable		 6f5uA-1jl5A:
10.47
6f5uB-1jl5A:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		5 / 10 VAL A1160
LEU A1165
LEU A1185
LEU A1149
LEU A1146
 None
 0.98A 6f5uA-1jl5A:
0.2
6f5uB-1jl5A:
undetectable		 6f5uA-1jl5A:
10.47
6f5uB-1jl5A:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		5 / 10 VAL A1324
LEU A1329
LEU A1349
LEU A1315
LEU A1312
 None
 0.88A 6f5uA-1jl5A:
0.2
6f5uB-1jl5A:
undetectable		 6f5uA-1jl5A:
10.47
6f5uB-1jl5A:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 7 LEU A1312
VAL A1284
LEU A1302
LEU A1299
 None
 0.54A 6g9bA-1jl5A:
0.0
6g9bB-1jl5A:
undetectable		 6g9bA-1jl5A:
10.47
6g9bB-1jl5A:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		4 / 7 VAL A1118
LEU A1123
LEU A1143
LEU A1109
 None
 0.75A 6g9bA-1jl5A:
0.0
6g9bB-1jl5A:
undetectable		 6g9bA-1jl5A:
10.47
6g9bB-1jl5A:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_B_FFOB403_0
(THYMIDYLATE SYNTHASE)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		5 / 10 ILE A1220
LEU A1262
ASP A1245
GLY A1223
ASN A1247
 None
 1.41A 6r2eB-1jl5A:
0.0		 6r2eB-1jl5A:
24.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_D_FFOD403_0
(THYMIDYLATE SYNTHASE)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		5 / 10 ILE A1220
LEU A1262
ASP A1245
GLY A1223
ASN A1247
 None
 1.46A 6r2eD-1jl5A:
0.1		 6r2eD-1jl5A:
24.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_F_FFOF403_0
(THYMIDYLATE SYNTHASE)		 1jl5 OUTER PROTEIN YOPM
(Yersinia
pestis) 		5 / 11 PHE A1177
ASN A1141
LEU A1123
LEU A1117
ALA A1098
 None
 1.32A 6r2eF-1jl5A:
0.1		 6r2eF-1jl5A:
24.95