SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jlv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_A_CLMA1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 1jlv GLUTATHIONE
TRANSFERASE GST1-3
(Anopheles
cracens) 		5 / 8 ALA A  19
LEU A  26
LEU A  28
ILE A 195
ILE A  52
 None
None
None
None
GSH  A 701 (-4.6A)
 1.41A 2uxpA-1jlvA:
undetectable		 2uxpA-1jlvA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_A_SALA257_1
(TRANSCRIPTIONAL
REGULATOR)		 1jlv GLUTATHIONE
TRANSFERASE GST1-3
(Anopheles
cracens) 		4 / 8 SER A  65
ARG A  66
ALA A  10
THR A 165
 GSH  A 701 (-2.5A)
GSH  A 701 (-3.5A)
None
None
 0.95A 3bpxA-1jlvA:
undetectable
3bpxB-1jlvA:
2.0		 3bpxA-1jlvA:
20.93
3bpxB-1jlvA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 1jlv GLUTATHIONE
TRANSFERASE GST1-3
(Anopheles
cracens) 		3 / 3 MET A 101
CYH A  69
PRO A  11
 GSH  A 701 (-3.7A)
None
GSH  A 701 ( 4.7A)
 1.28A 3h52C-1jlvA:
0.0		 3h52C-1jlvA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_4
(HIV-1 PROTEASE)		 1jlv GLUTATHIONE
TRANSFERASE GST1-3
(Anopheles
cracens) 		4 / 4 ARG A  66
ASP A  80
GLY A  77
THR A  18
 GSH  A 701 (-3.5A)
None
None
None
 1.34A 3k4vB-1jlvA:
undetectable		 3k4vB-1jlvA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1jlv GLUTATHIONE
TRANSFERASE GST1-3
(Anopheles
cracens) 		4 / 5 VAL A 168
SER A 164
GLY A 199
ARG A  13
 None
 1.28A 3v4tA-1jlvA:
undetectable
3v4tD-1jlvA:
undetectable		 3v4tA-1jlvA:
19.77
3v4tD-1jlvA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7G_A_ACTA514_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1jlv GLUTATHIONE
TRANSFERASE GST1-3
(Anopheles
cracens) 		4 / 4 ALA A 155
VAL A 159
ASP A 156
LEU A 141
 None
 0.81A 4e7gA-1jlvA:
0.0		 4e7gA-1jlvA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_1
(HIV-1 PROTEASE)		 1jlv GLUTATHIONE
TRANSFERASE GST1-3
(Anopheles
cracens) 		4 / 7 LEU A 152
ASP A 100
VAL A  93
ILE A  68
 None
 0.91A 4eyrA-1jlvA:
undetectable		 4eyrA-1jlvA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1jlv GLUTATHIONE
TRANSFERASE GST1-3
(Anopheles
cracens) 		3 / 3 GLY A 170
VAL A 134
MET A 130
 None
 0.64A 5ycpA-1jlvA:
undetectable		 5ycpA-1jlvA:
20.00