SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jlx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_2
(PROTEASE)		 1jlx AGGLUTININ
(Amaranthus
caudatus) 		4 / 6 ASN A 181
ASP A 226
GLY A 273
ILE A 180
 None
 0.89A 1n49D-1jlxA:
undetectable		 1n49D-1jlxA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 1jlx AGGLUTININ
(Amaranthus
caudatus) 		3 / 3 LEU A 193
TYR A 174
GLY A 189
 None
 0.60A 2ocuA-1jlxA:
undetectable		 2ocuA-1jlxA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMQ_A_BEZA3_0
(PROTEIN NDRG2)		 1jlx AGGLUTININ
(Amaranthus
caudatus) 		4 / 7 GLN A  32
PHE A  33
ARG A  19
HIS A  14
 None
 1.39A 2qmqA-1jlxA:
0.0		 2qmqA-1jlxA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1jlx AGGLUTININ
(Amaranthus
caudatus) 		3 / 3 ASN A 123
MET A   7
PHE A 149
 None
 1.00A 3g4lD-1jlxA:
undetectable		 3g4lD-1jlxA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA271_0
(PROTEIN SSM1)		 1jlx AGGLUTININ
(Amaranthus
caudatus) 		4 / 5 GLY A 169
LYS A 168
GLU A 295
GLY A 172
 None
 0.60A 3onnA-1jlxA:
undetectable		 3onnA-1jlxA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7B_C_ACTC513_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1jlx AGGLUTININ
(Amaranthus
caudatus) 		3 / 3 TYR A  76
HIS A 119
ARG A  70
 A2G  A 305 ( 3.4A)
None
None
 0.74A 4e7bC-1jlxA:
0.0		 4e7bC-1jlxA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 1jlx AGGLUTININ
(Amaranthus
caudatus) 		3 / 3 THR A  64
SER A  61
ASP A  40
 None
 0.84A 5kvaA-1jlxA:
undetectable		 5kvaA-1jlxA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 1jlx AGGLUTININ
(Amaranthus
caudatus) 		3 / 3 THR A  64
SER A  61
ASP A  40
 None
 0.86A 5kvaB-1jlxA:
undetectable		 5kvaB-1jlxA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_1
(SCRFP-TAG,GP41)		 1jlx AGGLUTININ
(Amaranthus
caudatus) 		5 / 12 GLY A 172
LYS A 173
ASN A 170
LEU A 294
GLU A 295
 None
 1.30A 5nwvA-1jlxA:
0.0		 5nwvA-1jlxA:
7.62