SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jm1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 1jm1 RIESKE IRON-SULFUR
PROTEIN SOXF
(Sulfolobus
acidocaldarius) 		4 / 6 ILE A  71
VAL A  67
VAL A 211
ILE A 124
 None
 0.81A 1uwhB-1jm1A:
undetectable		 1uwhB-1jm1A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VIF_A_FOLA1_0
(DIHYDROFOLATE
REDUCTASE)		 1jm1 RIESKE IRON-SULFUR
PROTEIN SOXF
(Sulfolobus
acidocaldarius) 		3 / 3 GLN A 120
ILE A 121
TYR A 111
 None
 0.68A 1vifA-1jm1A:
0.0		 1vifA-1jm1A:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1jm1 RIESKE IRON-SULFUR
PROTEIN SOXF
(Sulfolobus
acidocaldarius) 		5 / 12 ASP A 138
GLY A 182
ALA A 135
LEU A  95
ILE A 106
 None
 0.99A 3ku1H-1jm1A:
undetectable		 3ku1H-1jm1A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA500_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 1jm1 RIESKE IRON-SULFUR
PROTEIN SOXF
(Sulfolobus
acidocaldarius) 		4 / 4 ALA A 190
HIS A 142
HIS A 173
PRO A 189
 None
FES  A 501 (-3.2A)
FES  A 501 (-3.2A)
None
 1.37A 3mbgA-1jm1A:
undetectable		 3mbgA-1jm1A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC900_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 1jm1 RIESKE IRON-SULFUR
PROTEIN SOXF
(Sulfolobus
acidocaldarius) 		4 / 4 ALA A 190
HIS A 142
HIS A 173
PRO A 189
 None
FES  A 501 (-3.2A)
FES  A 501 (-3.2A)
None
 1.37A 3mbgC-1jm1A:
undetectable		 3mbgC-1jm1A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1jm1 RIESKE IRON-SULFUR
PROTEIN SOXF
(Sulfolobus
acidocaldarius) 		4 / 7 VAL A 197
ILE A 196
LEU A  98
LEU A  95
 None
 1.00A 4l1wA-1jm1A:
undetectable		 4l1wA-1jm1A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_B_ACTB202_0
(RETINOL-BINDING
PROTEIN 2)		 1jm1 RIESKE IRON-SULFUR
PROTEIN SOXF
(Sulfolobus
acidocaldarius) 		4 / 7 TYR A 110
TYR A 177
LEU A 194
ARG A 192
 None
 1.47A 4qzuB-1jm1A:
0.0		 4qzuB-1jm1A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1jm1 RIESKE IRON-SULFUR
PROTEIN SOXF
(Sulfolobus
acidocaldarius) 		4 / 7 VAL A 197
ILE A 196
LEU A  98
LEU A  95
 None
 0.95A 4xo7A-1jm1A:
undetectable		 4xo7A-1jm1A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1jm1 RIESKE IRON-SULFUR
PROTEIN SOXF
(Sulfolobus
acidocaldarius) 		4 / 8 VAL A  93
ASP A  94
GLN A  96
GLY A 100
 None
 0.68A 5w3jB-1jm1A:
undetectable		 5w3jB-1jm1A:
17.07