SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jm7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		 1jm7 BREAST CANCER TYPE 1
SUSCEPTIBILITY
PROTEIN
(Homo
sapiens) 		5 / 12 ILE A  21
LEU A  87
VAL A  83
GLU A  23
LEU A  30
 None
 1.33A 2bxfB-1jm7A:
undetectable		 2bxfB-1jm7A:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 1jm7 BREAST CANCER TYPE 1
SUSCEPTIBILITY
PROTEIN
(Homo
sapiens) 		4 / 5 LYS A  45
SER A  80
LEU A  73
SER A  36
 None
 1.43A 3ijxH-1jm7A:
undetectable		 3ijxH-1jm7A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 1jm7 BREAST CANCER TYPE 1
SUSCEPTIBILITY
PROTEIN
(Homo
sapiens) 		4 / 4 LYS A  45
SER A  80
LEU A  73
SER A  36
 None
 1.41A 3ik6H-1jm7A:
undetectable		 3ik6H-1jm7A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 1jm7 BREAST CANCER TYPE 1
SUSCEPTIBILITY
PROTEIN
(Homo
sapiens) 		4 / 5 LYS A  45
SER A  80
LEU A  73
SER A  36
 None
 1.37A 3iluH-1jm7A:
undetectable		 3iluH-1jm7A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_2
(CYCLIN-DEPENDENT
KINASE 6)		 1jm7 BRCA1-ASSOCIATED
RING DOMAIN PROTEIN
1
BREAST CANCER TYPE 1
SUSCEPTIBILITY
PROTEIN
(Homo
sapiens) 		3 / 3 LYS B 110
GLN A  19
ASN A  16
 None
 0.96A 5l2tA-1jm7B:
undetectable		 5l2tA-1jm7B:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_A_SALA201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1jm7 BRCA1-ASSOCIATED
RING DOMAIN PROTEIN
1
(Homo
sapiens) 		4 / 5 VAL B  75
ARG B  52
PRO B  84
GLY B  82
 None
 1.14A 5x80A-1jm7B:
undetectable
5x80B-1jm7B:
undetectable		 5x80A-1jm7B:
21.12
5x80B-1jm7B:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1jm7 BRCA1-ASSOCIATED
RING DOMAIN PROTEIN
1
(Homo
sapiens) 		4 / 5 PRO B  84
GLY B  82
VAL B  75
ARG B  52
 None
 1.16A 5x80C-1jm7B:
undetectable
5x80D-1jm7B:
undetectable		 5x80C-1jm7B:
21.12
5x80D-1jm7B:
21.12