SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jmk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDS_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 1jmk SURFACTIN SYNTHETASE
(Bacillus
subtilis) 		5 / 12 VAL C 168
GLY C 166
SER C 189
PHE C  87
MET C 105
 None
 1.32A 1fdsA-1jmkC:
5.1		 1fdsA-1jmkC:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_1
(HMG-COA REDUCTASE)		 1jmk SURFACTIN SYNTHETASE
(Bacillus
subtilis) 		5 / 9 ASN C  14
LEU C  41
ALA C 220
LEU C 223
LEU C 211
 SO4  C 502 (-4.6A)
None
None
None
None
 1.46A 1hwiA-1jmkC:
0.0		 1hwiA-1jmkC:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1jmk SURFACTIN SYNTHETASE
(Bacillus
subtilis) 		4 / 8 LEU C  41
SER C  38
LEU C 175
ILE C  21
 None
 0.90A 3ln1A-1jmkC:
undetectable		 3ln1A-1jmkC:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1jmk SURFACTIN SYNTHETASE
(Bacillus
subtilis) 		4 / 7 LEU C  41
SER C  38
LEU C 175
ILE C  21
 None
 0.89A 3ln1B-1jmkC:
0.0		 3ln1B-1jmkC:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 1jmk SURFACTIN SYNTHETASE
(Bacillus
subtilis) 		4 / 7 PHE C  49
PHE C  24
ALA C  62
LEU C  76
 None
 1.07A 4ejgA-1jmkC:
0.0		 4ejgA-1jmkC:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 1jmk SURFACTIN SYNTHETASE
(Bacillus
subtilis) 		5 / 8 PHE C  49
PHE C  24
ALA C  62
LEU C  74
LEU C  76
 None
 1.14A 4ejgB-1jmkC:
0.0		 4ejgB-1jmkC:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 1jmk SURFACTIN SYNTHETASE
(Bacillus
subtilis) 		4 / 6 PHE C  49
PHE C  24
ALA C  62
LEU C  74
 None
 1.02A 4ejgD-1jmkC:
0.0		 4ejgD-1jmkC:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1N_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1jmk SURFACTIN SYNTHETASE
(Bacillus
subtilis) 		5 / 11 ILE C 222
ALA C 220
LEU C 227
PHE C 226
ARG C 199
 None
 1.33A 4i1nA-1jmkC:
undetectable		 4i1nA-1jmkC:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LA0_A_198A601_1
(SERUM ALBUMIN)		 1jmk SURFACTIN SYNTHETASE
(Bacillus
subtilis) 		5 / 10 LEU C 224
ARG C  40
ALA C  23
PHE C  77
LEU C 216
 None
 1.44A 4la0A-1jmkC:
undetectable		 4la0A-1jmkC:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_1_BEZ1801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1jmk SURFACTIN SYNTHETASE
(Bacillus
subtilis) 		3 / 3 LEU C  64
PHE C  24
ILE C  65
 None
 0.76A 5dzk1-1jmkC:
undetectable
5dzkF-1jmkC:
1.5
5dzkM-1jmkC:
0.1		 5dzk1-1jmkC:
1.15
5dzkF-1jmkC:
22.92
5dzkM-1jmkC:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1jmk SURFACTIN SYNTHETASE
(Bacillus
subtilis) 		4 / 5 SER C  80
ALA C  81
HIS C 207
LEU C 129
 None
 1.26A 5dzkb-1jmkC:
2.7
5dzkp-1jmkC:
undetectable		 5dzkb-1jmkC:
22.92
5dzkp-1jmkC:
1.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1jmk SURFACTIN SYNTHETASE
(Bacillus
subtilis) 		4 / 5 SER C  80
ALA C  81
HIS C 207
LEU C 129
 None
 1.29A 5dzkc-1jmkC:
0.6
5dzkq-1jmkC:
undetectable		 5dzkc-1jmkC:
22.92
5dzkq-1jmkC:
1.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1jmk SURFACTIN SYNTHETASE
(Bacillus
subtilis) 		4 / 8 SER C  80
ALA C  81
HIS C 207
LEU C 129
 None
 1.14A 5dzkd-1jmkC:
2.9
5dzkr-1jmkC:
undetectable		 5dzkd-1jmkC:
22.92
5dzkr-1jmkC:
1.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1jmk SURFACTIN SYNTHETASE
(Bacillus
subtilis) 		4 / 5 SER C  80
ALA C  81
HIS C 207
LEU C 129
 None
 1.30A 5dzkf-1jmkC:
1.5
5dzkt-1jmkC:
undetectable		 5dzkf-1jmkC:
22.92
5dzkt-1jmkC:
1.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1jmk SURFACTIN SYNTHETASE
(Bacillus
subtilis) 		4 / 6 SER C  80
ALA C  81
HIS C 207
LEU C 129
 None
 1.27A 5dzkg-1jmkC:
1.7
5dzku-1jmkC:
undetectable		 5dzkg-1jmkC:
22.92
5dzku-1jmkC:
1.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6F_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1jmk SURFACTIN SYNTHETASE
(Bacillus
subtilis) 		5 / 12 ILE C 222
ALA C 220
LEU C 227
PHE C 226
ARG C 199
 None
 1.29A 5z6fA-1jmkC:
undetectable		 5z6fA-1jmkC:
20.09