SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jmt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RG1_A_SPMA999_1 (TYROSYL-DNA PHOSPHODIESTERASE 1)	1jmt	SPLICING FACTOR U2AF 35 KDA SUBUNIT SPLICING FACTOR U2AF 65 KDA SUBUNIT (Homo sapiens)	3 / 3	TRP A 134 VAL B 94 PRO B 95	None	0.80A	1rg1A-1jmtA: 0.0	1rg1A-1jmtA: 12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RH0_A_SPMA999_1 (TYROSYL-DNA PHOSPHODIESTERASE 1)	1jmt	SPLICING FACTOR U2AF 35 KDA SUBUNIT SPLICING FACTOR U2AF 65 KDA SUBUNIT (Homo sapiens)	3 / 3	TRP A 134 VAL B 94 PRO B 95	None	0.80A	1rh0A-1jmtA: 0.0	1rh0A-1jmtA: 12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GQI_A_ACTA604_0 (CYCLOHEXANONE MONOOXYGENASE FROM THERMOCRISPUM MUNICIPALE)	1jmt	SPLICING FACTOR U2AF 35 KDA SUBUNIT SPLICING FACTOR U2AF 65 KDA SUBUNIT (Homo sapiens; Homo sapiens)	4 / 6	PRO B 95 TRP A 134 ILE B 102 GLY B 98	None None HEZ B 201 ( 4.7A) None	1.14A	6gqiA-1jmtB: undetectable	6gqiA-1jmtB: 3.88