SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jmu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_A_SAMA5635_0
(PROTEIN RDMB)		 1jmu PROTEIN MU-1
PROTEIN MU-1
(Reovirus
sp.;
Reovirus
sp.) 		5 / 12 GLY B 246
GLY B 245
LEU B 240
PHE A  20
SER A  23
 None
None
BOG  B 709 (-4.6A)
None
None
 1.19A 1xdsA-1jmuB:
undetectable		 1xdsA-1jmuB:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 1jmu PROTEIN MU-1
(Reovirus
sp.) 		5 / 11 LEU B 326
GLU B 330
LEU B 527
SER B 530
ASP B 534
 None
 1.37A 2c12F-1jmuB:
undetectable		 2c12F-1jmuB:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1jmu PROTEIN MU-1
(Reovirus
sp.) 		4 / 7 TRP B 413
GLY B 363
THR B 343
PHE B 404
 None
SO4  B 710 (-3.4A)
None
None
 1.11A 2qx4A-1jmuB:
undetectable
2qx4B-1jmuB:
undetectable		 2qx4A-1jmuB:
15.78
2qx4B-1jmuB:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1jmu PROTEIN MU-1
(Reovirus
sp.) 		4 / 8 TYR B 137
VAL B 175
TYR B 174
LEU A  36
 None
 0.97A 4jtrA-1jmuB:
undetectable		 4jtrA-1jmuB:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)		 1jmu PROTEIN MU-1
(Reovirus
sp.) 		3 / 3 ASP B 553
TRP B 624
SER B 562
 None
 0.87A 4lrhA-1jmuB:
undetectable		 4lrhA-1jmuB:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_H_SPMH202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1jmu PROTEIN MU-1
(Reovirus
sp.) 		4 / 6 ASN B 451
TYR B 452
GLU B 453
GLU B 455
 None
 1.47A 4r87H-1jmuB:
0.0		 4r87H-1jmuB:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 1jmu PROTEIN MU-1
(Reovirus
sp.) 		4 / 8 GLU B 560
ASP B 559
SER B 597
ARG B 598
 None
 0.99A 4uhxA-1jmuB:
undetectable		 4uhxA-1jmuB:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 1jmu PROTEIN MU-1
(Reovirus
sp.) 		4 / 8 GLU B 560
ASP B 559
SER B 597
ARG B 598
 None
 0.99A 4uhxA-1jmuB:
undetectable		 4uhxA-1jmuB:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G44_A_YTZA1512_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 1jmu PROTEIN MU-1
(Reovirus
sp.) 		5 / 9 LEU B 326
LEU B 334
ALA B 491
ARG B 324
ARG B 366
 None
 1.43A 5g44A-1jmuB:
0.0		 5g44A-1jmuB:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jmu PROTEIN MU-1
(Reovirus
sp.) 		4 / 5 ARG B 377
MET B 495
THR B 494
LEU B 493
 None
 0.96A 5x19J-1jmuB:
0.0		 5x19J-1jmuB:
7.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jmu PROTEIN MU-1
(Reovirus
sp.) 		4 / 5 ARG B 377
MET B 495
THR B 494
LEU B 493
 None
 0.92A 5x1bJ-1jmuB:
0.0		 5x1bJ-1jmuB:
7.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jmu PROTEIN MU-1
(Reovirus
sp.) 		4 / 6 ARG B 377
MET B 495
THR B 494
LEU B 493
 None
 1.04A 5x1fA-1jmuB:
undetectable
5x1fJ-1jmuB:
0.0		 5x1fA-1jmuB:
22.47
5x1fJ-1jmuB:
7.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11803_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
EL18)		 1jmu PROTEIN MU-1
(Reovirus
sp.) 		3 / 3 SER B 593
LYS B 594
SER B 597
 None
 0.78A 6az3P-1jmuB:
0.0		 6az3P-1jmuB:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11803_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
EL18)		 1jmu PROTEIN MU-1
(Reovirus
sp.) 		3 / 3 SER B 649
LYS B 650
SER B 653
 None
 0.66A 6az3P-1jmuB:
0.0		 6az3P-1jmuB:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1jmu PROTEIN MU-1
(Reovirus
sp.) 		4 / 6 SER B 406
TYR B 467
GLN B 418
GLU B 411
 None
 1.27A 6djzA-1jmuB:
2.6		 6djzA-1jmuB:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1jmu PROTEIN MU-1
(Reovirus
sp.) 		3 / 3 LEU B 219
ASN B 202
LEU B 665
 BOG  B 709 ( 4.4A)
None
None
 0.64A 6exiA-1jmuB:
undetectable		 6exiA-1jmuB:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FDY_U_DB8U302_1
(-)		 1jmu PROTEIN MU-1
(Reovirus
sp.) 		5 / 9 LEU A  34
SER B 134
LEU B 118
GLU B 115
ILE B 178
 None
 1.32A 6fdyU-1jmuA:
undetectable		 6fdyU-1jmuA:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jmu PROTEIN MU-1
(Reovirus
sp.) 		4 / 5 ARG B 377
MET B 495
THR B 494
LEU B 493
 None
 1.15A 6nknJ-1jmuB:
1.0		 6nknJ-1jmuB:
7.95