SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jmy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 8 GLY A 107
GLU A 193
SER A 194
PHE A 324
HIS A 435
 None
 0.72A 1ax9A-1jmyA:
49.2		 1ax9A-1jmyA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_A_SAMA105_0
(MET REPRESSOR)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 10 ALA A 251
GLY A 249
LEU A 158
LEU A 234
PRO A 233
 None
 1.22A 1cmcA-1jmyA:
undetectable
1cmcB-1jmyA:
undetectable		 1cmcA-1jmyA:
11.61
1cmcB-1jmyA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_1
(TRANSTHYRETIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 7 LYS A 361
LEU A 357
ALA A 360
THR A 352
 None
 0.74A 1dvxA-1jmyA:
0.0		 1dvxA-1jmyA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 7 LYS A 361
LEU A 357
ALA A 360
THR A 352
 None
 0.76A 1dvxB-1jmyA:
0.0		 1dvxB-1jmyA:
12.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		6 / 12 GLY A 106
GLY A 107
SER A 194
TRP A 227
PHE A 324
HIS A 435
 None
 0.47A 1dx6A-1jmyA:
51.6		 1dx6A-1jmyA:
32.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 12 GLY A 107
SER A 194
TRP A 227
PHE A 324
HIS A 435
 None
 0.86A 1dx6A-1jmyA:
51.6		 1dx6A-1jmyA:
32.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4008_1
(SERUM ALBUMIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 8 ALA A 251
LEU A 258
LEU A 234
ALA A 237
LYS A 238
 None
 1.18A 1e7cA-1jmyA:
undetectable		 1e7cA-1jmyA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 7 LEU A  65
THR A 267
LEU A 151
GLY A 149
 None
 0.94A 1gtiB-1jmyA:
undetectable		 1gtiB-1jmyA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 6 LYS A 361
LEU A 357
ALA A 360
THR A 352
 None
 1.07A 1ictB-1jmyA:
undetectable		 1ictB-1jmyA:
12.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_C_DMEC997_1
(ACETYLCHOLINESTERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 12 GLY A 107
TYR A 125
SER A 194
PHE A 324
HIS A 435
 None
 0.57A 1maaC-1jmyA:
46.8		 1maaC-1jmyA:
34.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 8 GLY A 107
GLU A 193
SER A 194
HIS A 435
 None
 0.34A 1maaD-1jmyA:
42.9		 1maaD-1jmyA:
34.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 12 ALA A 251
GLY A 249
LEU A 158
LEU A 234
PRO A 233
 None
 1.11A 1mjqC-1jmyA:
undetectable
1mjqD-1jmyA:
undetectable		 1mjqC-1jmyA:
11.20
1mjqD-1jmyA:
11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 12 ALA A 251
GLY A 249
LEU A 158
LEU A 234
PRO A 233
 None
 1.11A 1mjqI-1jmyA:
undetectable
1mjqJ-1jmyA:
undetectable		 1mjqI-1jmyA:
11.20
1mjqJ-1jmyA:
11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_2
(ANGIOTENSIN
CONVERTING ENZYME)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 4 SER A 422
VAL A 431
PHE A 418
VAL A 460
 None
 1.34A 1o86A-1jmyA:
0.0		 1o86A-1jmyA:
22.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		6 / 12 GLY A 106
GLY A 107
GLU A 193
SER A 194
PHE A 324
HIS A 435
 None
 0.57A 1qtiA-1jmyA:
50.7		 1qtiA-1jmyA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		6 / 12 GLY A 106
GLY A 107
GLU A 193
SER A 194
PHE A 324
HIS A 435
 None
 0.78A 1qtiA-1jmyA:
50.7		 1qtiA-1jmyA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 6 LYS A 361
LEU A 357
ALA A 360
THR A 352
 None
 0.94A 1tyrA-1jmyA:
0.0		 1tyrA-1jmyA:
12.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 12 GLY A 106
GLY A 107
SER A 194
PHE A 324
HIS A 435
 None
 0.51A 1w6rA-1jmyA:
51.5		 1w6rA-1jmyA:
32.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 12 GLY A 106
GLY A 107
SER A 194
PHE A 324
HIS A 435
 None
 0.80A 1w6rA-1jmyA:
51.5		 1w6rA-1jmyA:
32.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 11 GLY A 107
GLU A 193
SER A 194
PHE A 324
HIS A 435
 None
 0.52A 1w76A-1jmyA:
51.6		 1w76A-1jmyA:
32.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		6 / 10 GLY A 106
GLY A 107
GLU A 193
SER A 194
PHE A 324
HIS A 435
 None
 0.46A 1w76B-1jmyA:
51.5		 1w76B-1jmyA:
32.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 8 GLY A 106
GLY A 107
SER A 194
ALA A 195
HIS A 435
 None
 0.29A 1yajC-1jmyA:
47.2		 1yajC-1jmyA:
35.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 8 GLY A 196
GLY A 106
GLY A 107
ALA A 195
HIS A 435
 None
 1.07A 1yajC-1jmyA:
47.2		 1yajC-1jmyA:
35.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 12 HIS A 168
LEU A  83
LEU A  81
ILE A 102
SER A 206
 None
 1.27A 1zq9A-1jmyA:
undetectable		 1zq9A-1jmyA:
20.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 9 GLY A 106
GLY A 107
SER A 194
ALA A 195
HIS A 435
 None
 0.85A 2aceA-1jmyA:
53.4		 2aceA-1jmyA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 9 GLY A 107
SER A 194
ALA A 195
TRP A 227
HIS A 435
 None
 0.34A 2aceA-1jmyA:
53.4		 2aceA-1jmyA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 7 GLY A 107
GLU A 193
SER A 194
PHE A 324
HIS A 435
 None
 0.73A 2ackA-1jmyA:
52.0		 2ackA-1jmyA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 12 LEU A   3
LEU A  98
ILE A 137
ILE A 178
ALA A 179
 None
 0.85A 2bxqA-1jmyA:
0.4		 2bxqA-1jmyA:
22.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 8 TYR A 125
GLU A 193
PHE A 324
HIS A 435
 None
 0.57A 2ha4A-1jmyA:
46.3		 2ha4A-1jmyA:
34.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 8 GLY A 107
ALA A 195
TRP A 227
HIS A 435
 None
 0.27A 2ha4A-1jmyA:
46.3		 2ha4A-1jmyA:
34.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 7 GLY A 107
ALA A 195
TRP A 227
HIS A 435
 None
 0.27A 2ha4B-1jmyA:
50.3		 2ha4B-1jmyA:
34.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_B_T44B128_1
(TRANSTHYRETIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 6 LYS A 361
LEU A 357
ALA A 360
THR A 352
 None
 0.97A 2roxB-1jmyA:
0.0		 2roxB-1jmyA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1498_1
(CYTOCHROME P450 3A4)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 11 LEU A 234
ALA A 241
ARG A 144
GLU A  43
LEU A 151
 None
 1.32A 2v0mD-1jmyA:
0.0		 2v0mD-1jmyA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 7 THR A 363
GLY A 359
PHE A 387
THR A 352
 None
 0.94A 2vl2B-1jmyA:
undetectable		 2vl2B-1jmyA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 12 GLY A  15
ALA A   5
ASP A 126
ASP A  28
VAL A  27
 None
 1.01A 2yvlD-1jmyA:
undetectable		 2yvlD-1jmyA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZTH_A_SAMA305_0
(CATECHOL
O-METHYLTRANSFERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 12 VAL A 290
GLY A 146
MET A 111
TYR A 143
GLN A  71
 None
 1.42A 2zthA-1jmyA:
2.7		 2zthA-1jmyA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_A_DIFA1_1
(TRANSTHYRETIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 6 LYS A 361
LEU A 357
ALA A 360
THR A 352
 None
 0.71A 3cfqA-1jmyA:
0.0		 3cfqA-1jmyA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_A_EPAA1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 12 GLY A 197
ALA A 198
SER A 201
LEU A 202
LEU A 205
 None
 0.86A 3hs6A-1jmyA:
0.0		 3hs6A-1jmyA:
20.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O9M_A_BEZA999_0
(CHOLINESTERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 7 GLY A 107
SER A 194
TRP A 227
PHE A 393
HIS A 435
 None
 0.59A 3o9mA-1jmyA:
52.7		 3o9mA-1jmyA:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 6 GLY A 107
SER A 194
TRP A 227
HIS A 435
 None
 0.45A 3o9mB-1jmyA:
52.7		 3o9mB-1jmyA:
34.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OI8_A_ADNA2_1
(UNCHARACTERIZED
PROTEIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 6 ILE A 301
HIS A 522
PRO A 396
LEU A 224
 None
 1.29A 3oi8A-1jmyA:
undetectable		 3oi8A-1jmyA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 7 LYS A 361
LEU A 357
ALA A 360
THR A 352
 None
 1.00A 3ozkB-1jmyA:
undetectable		 3ozkB-1jmyA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 8 PHE A 235
PRO A 233
GLY A 286
PHE A 287
 None
 1.02A 3tzfB-1jmyA:
undetectable		 3tzfB-1jmyA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOA_A_ACRA1587_2
(TREHALOSE
SYNTHASE/AMYLASE
TRES)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		3 / 3 ARG A 133
PHE A 447
PRO A 446
 None
 0.83A 3zoaB-1jmyA:
undetectable		 3zoaB-1jmyA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 7 ILE A 521
PHE A 351
TYR A 367
VAL A 339
 None
 1.07A 4a97A-1jmyA:
0.0		 4a97A-1jmyA:
20.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 12 GLY A 106
GLY A 107
SER A 194
PHE A 324
HIS A 435
 None
 0.42A 4ey6A-1jmyA:
50.0		 4ey6A-1jmyA:
33.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 12 GLY A 106
GLY A 107
SER A 194
PHE A 324
HIS A 435
 None
 0.88A 4ey6A-1jmyA:
50.0		 4ey6A-1jmyA:
33.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		6 / 12 GLY A 106
GLY A 107
GLU A 193
SER A 194
PHE A 324
HIS A 435
 None
 0.41A 4ey6B-1jmyA:
43.3		 4ey6B-1jmyA:
33.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		6 / 12 GLY A 106
GLY A 107
GLU A 193
SER A 194
PHE A 324
HIS A 435
 None
 0.88A 4ey6B-1jmyA:
43.3		 4ey6B-1jmyA:
33.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 6 LYS A 361
LEU A 357
ALA A 360
THR A 352
 None
 0.82A 4i89A-1jmyA:
undetectable		 4i89A-1jmyA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 7 LYS A 361
LEU A 357
ALA A 360
THR A 352
VAL A 348
 None
 1.44A 4ik7A-1jmyA:
0.0		 4ik7A-1jmyA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 8 LYS A 361
LEU A 357
ALA A 360
THR A 352
 None
 0.82A 4ik7B-1jmyA:
undetectable		 4ik7B-1jmyA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_B_IMNB201_1
(TRANSTHYRETIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 6 LYS A 361
LEU A 357
ALA A 360
THR A 352
 None
 0.94A 4ikiB-1jmyA:
undetectable		 4ikiB-1jmyA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 7 LYS A 361
LEU A 357
ALA A 360
THR A 352
 None
 1.04A 4ikjA-1jmyA:
undetectable
4ikjB-1jmyA:
undetectable		 4ikjA-1jmyA:
12.64
4ikjB-1jmyA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 8 LYS A 361
LEU A 357
ALA A 360
THR A 352
 None
 0.91A 4ikjA-1jmyA:
undetectable
4ikjB-1jmyA:
undetectable		 4ikjA-1jmyA:
12.64
4ikjB-1jmyA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 7 LYS A 361
LEU A 357
ALA A 360
THR A 352
 None
 0.87A 4ikkA-1jmyA:
undetectable
4ikkB-1jmyA:
undetectable		 4ikkA-1jmyA:
12.64
4ikkB-1jmyA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 8 LYS A 361
LEU A 357
ALA A 360
THR A 352
 None
 0.79A 4iklA-1jmyA:
undetectable
4iklB-1jmyA:
undetectable		 4iklA-1jmyA:
12.64
4iklB-1jmyA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 7 TYR A 312
ILE A 217
ASP A 476
GLY A 475
 None
 0.87A 4iqqB-1jmyA:
undetectable		 4iqqB-1jmyA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 7 PHE A 324
ASP A 320
SER A 220
ALA A 436
 None
 0.92A 4lv9A-1jmyA:
undetectable
4lv9B-1jmyA:
undetectable		 4lv9A-1jmyA:
21.84
4lv9B-1jmyA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NED_A_PFNA709_1
(LACTOTRANSFERRIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 6 VAL A 145
SER A 199
ALA A 170
PHE A  35
 None
 1.21A 4nedA-1jmyA:
undetectable		 4nedA-1jmyA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0O_A_URFA303_1
(RRNA N-GLYCOSIDASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 5 TYR A 125
ASN A 142
TYR A 143
ILE A 104
 None
 1.41A 4o0oA-1jmyA:
undetectable		 4o0oA-1jmyA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 12 GLY A 197
ALA A 198
SER A 201
LEU A 202
LEU A 205
 None
 0.71A 4o1zA-1jmyA:
undetectable		 4o1zA-1jmyA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 7 LYS A 361
LEU A 357
ALA A 360
THR A 352
 None
 0.94A 4pwjB-1jmyA:
0.0		 4pwjB-1jmyA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		3 / 3 THR A 492
ASN A 495
SER A 496
 None
 0.69A 4tvtA-1jmyA:
0.0		 4tvtA-1jmyA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_1
(ADENOSINE KINASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 12 GLY A 149
GLY A 146
PHE A 287
ALA A  67
GLN A  71
 None
 1.07A 4ubeA-1jmyA:
4.1		 4ubeA-1jmyA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 12 GLU A 494
ILE A 501
GLY A 315
THR A 397
LEU A 514
 None
 1.25A 5esgA-1jmyA:
0.0		 5esgA-1jmyA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		5 / 12 GLN A  71
ALA A  67
GLY A 106
ALA A 195
SER A 194
 None
 1.09A 5kirB-1jmyA:
0.0		 5kirB-1jmyA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_B_6J3B201_0
(TRANSTHYRETIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 6 LYS A 361
LEU A 357
ALA A 360
THR A 352
 None
 1.22A 5l4iB-1jmyA:
undetectable		 5l4iB-1jmyA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		3 / 3 THR A 502
PRO A 425
ARG A 423
 None
 0.79A 5nd7B-1jmyA:
2.3		 5nd7B-1jmyA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_2
(PROTEIN CYP51)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 6 TYR A 143
PRO A 147
LEU A 151
PHE A 150
 None
 1.03A 5tl8A-1jmyA:
0.0		 5tl8A-1jmyA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 1jmy BILE-SALT-ACTIVATED
LIPASE
(Homo
sapiens) 		4 / 4 LEU A  65
ASP A 262
PRO A 263
ARG A 264
 None
 1.27A 6fgdA-1jmyA:
2.9		 6fgdA-1jmyA:
21.51