SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jn0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA154_1
(CALMODULIN)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		5 / 10 GLU O 261
ALA O 263
LEU O 271
LEU O 161
GLU O 254
 None
 1.39A 1a29A-1jn0O:
0.0		 1a29A-1jn0O:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		3 / 3 ASP O 323
ARG O 320
ILE O 270
 None
 0.90A 1a4gB-1jn0O:
undetectable		 1a4gB-1jn0O:
22.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		4 / 7 ASN O 313
TYR O 317
ASN O 152
TYR O 311
 NDP  O6335 (-3.9A)
NDP  O6335 (-3.4A)
None
None
 0.83A 1dssG-1jn0O:
49.6		 1dssG-1jn0O:
44.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		7 / 7 SER O 148
THR O 150
ASN O 152
CYH O 153
TYR O 311
ASN O 313
TYR O 317
 SO4  O6337 (-3.5A)
SO4  O6337 (-3.9A)
None
None
None
NDP  O6335 (-3.9A)
NDP  O6335 (-3.4A)
 0.27A 1dssG-1jn0O:
49.6		 1dssG-1jn0O:
44.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		4 / 8 ASN O 313
TYR O 317
ASN O 152
TYR O 311
 NDP  O6335 (-3.9A)
NDP  O6335 (-3.4A)
None
None
 0.82A 1dssR-1jn0O:
49.4		 1dssR-1jn0O:
44.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		8 / 8 SER O 148
THR O 150
ASN O 152
CYH O 153
HIS O 176
TYR O 311
ASN O 313
TYR O 317
 SO4  O6337 (-3.5A)
SO4  O6337 (-3.9A)
None
None
None
None
NDP  O6335 (-3.9A)
NDP  O6335 (-3.4A)
 0.44A 1dssR-1jn0O:
49.4		 1dssR-1jn0O:
44.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		4 / 6 PHE O   8
VAL O  57
VAL O  73
ASP O  32
 None
 1.17A 1dz4A-1jn0O:
0.0		 1dz4A-1jn0O:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		4 / 6 PHE O   8
VAL O  57
VAL O  73
ASP O  32
 None
 1.15A 1dz4B-1jn0O:
0.0		 1dz4B-1jn0O:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G60_B_SAMB501_0
(ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		5 / 12 ASN O  31
ASP O 101
ILE O 143
PHE O  99
GLY O 106
 NDP  O6335 (-3.5A)
None
None
NDP  O6335 (-4.9A)
None
 1.48A 1g60B-1jn0O:
0.0		 1g60B-1jn0O:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_A_BEZA1501_0
(ANTHRANILATE
SYNTHASE)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		5 / 11 ILE O  93
GLY O  95
THR O 119
LEU O  16
GLY O   9
 None
NDP  O6335 (-4.6A)
NDP  O6335 (-4.5A)
None
NDP  O6335 (-3.5A)
 1.38A 1i7qA-1jn0O:
undetectable		 1i7qA-1jn0O:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_A_SAMA1300_0
(UPF0088 PROTEIN
AQ_165)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		5 / 12 VAL O 214
GLY O 209
LEU O 242
THR O 174
THR O 151
 None
SO4  O6337 (-3.7A)
None
None
None
 1.07A 2egvA-1jn0O:
2.7		 2egvA-1jn0O:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		4 / 6 THR O  96
THR O  33
ASP O  76
ASN O  81
 NDP  O6335 (-4.3A)
NDP  O6335 (-3.3A)
None
None
 1.21A 2okcA-1jn0O:
2.4		 2okcA-1jn0O:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		4 / 8 ASN O 313
TYR O 317
ASN O 152
TYR O 311
 NDP  O6335 (-3.9A)
NDP  O6335 (-3.4A)
None
None
 0.85A 3dmtC-1jn0O:
48.9		 3dmtC-1jn0O:
44.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		8 / 8 SER O 148
THR O 150
ASN O 152
CYH O 153
HIS O 176
TYR O 311
ASN O 313
TYR O 317
 SO4  O6337 (-3.5A)
SO4  O6337 (-3.9A)
None
None
None
None
NDP  O6335 (-3.9A)
NDP  O6335 (-3.4A)
 0.36A 3dmtC-1jn0O:
48.9		 3dmtC-1jn0O:
44.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2O_C_AG2C1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		4 / 8 HIS O 176
LEU O  50
TRP O 315
ASP O 312
 None
 1.02A 3n2oC-1jn0O:
undetectable
3n2oD-1jn0O:
undetectable		 3n2oC-1jn0O:
19.37
3n2oD-1jn0O:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_E_MTXE2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		5 / 12 ALA O 257
SER O 294
SER O 295
VAL O 160
ALA O 263
 None
 1.33A 3qxvE-1jn0O:
undetectable		 3qxvE-1jn0O:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		5 / 10 ILE O 125
SER O 148
ILE O 118
ALA O 105
GLU O  94
 None
SO4  O6337 (-3.5A)
None
None
None
 1.42A 3u6tA-1jn0O:
undetectable		 3u6tA-1jn0O:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_A_HFGA1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		5 / 12 PHE O 157
VAL O 160
THR O 208
SER O 148
GLY O 209
 None
None
SO4  O6337 (-3.4A)
SO4  O6337 (-3.5A)
SO4  O6337 (-3.7A)
 1.39A 4hvcA-1jn0O:
5.1		 4hvcA-1jn0O:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		5 / 12 LEU O 267
PHE O 157
VAL O 160
THR O 208
SER O 148
 None
None
None
SO4  O6337 (-3.4A)
SO4  O6337 (-3.5A)
 1.17A 4hvcB-1jn0O:
5.3		 4hvcB-1jn0O:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLF_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		5 / 12 PHE O 157
VAL O 160
THR O 208
SER O 148
GLY O 209
 None
None
SO4  O6337 (-3.4A)
SO4  O6337 (-3.5A)
SO4  O6337 (-3.7A)
 1.35A 4olfA-1jn0O:
2.5		 4olfA-1jn0O:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		5 / 11 SER O 148
LEU O 154
PRO O 156
VAL O 129
THR O 127
 SO4  O6337 (-3.5A)
None
None
None
None
 1.19A 4uuuB-1jn0O:
undetectable		 4uuuB-1jn0O:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		4 / 4 GLY O  34
LEU O  16
PHE O  15
ILE O   5
 None
 0.94A 4xv2A-1jn0O:
0.0		 4xv2A-1jn0O:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		3 / 3 THR O 151
ALA O 147
ASN O 152
 None
 0.62A 5ersA-1jn0O:
undetectable		 5ersA-1jn0O:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		4 / 5 THR O 138
HIS O 139
ALA O 140
ASP O 141
 None
 1.36A 5mfxA-1jn0O:
undetectable		 5mfxA-1jn0O:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		4 / 6 LEU O 267
VAL O 288
THR O 286
LEU O 242
 None
 0.96A 5tudD-1jn0O:
undetectable		 5tudD-1jn0O:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_2
(CYTOCHROME P450 2C9)		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		3 / 3 LEU O  25
VAL O 322
ASP O 323
 None
 0.66A 5x23A-1jn0O:
0.0		 5x23A-1jn0O:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A
(Spinacia
oleracea) 		5 / 12 LEU O 267
PHE O 157
VAL O 160
THR O 208
SER O 148
 None
None
None
SO4  O6337 (-3.4A)
SO4  O6337 (-3.5A)
 1.12A 5xiqB-1jn0O:
5.1		 5xiqB-1jn0O:
21.44