SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jnf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		5 / 12 GLY A 127
LEU A  66
SER A 125
ALA A 126
SER A 181
 CO3  A 700 (-3.9A)
None
CO3  A 700 ( 4.5A)
CO3  A 700 (-3.4A)
None
 1.16A 1dfoA-1jnfA:
undetectable		 1dfoA-1jnfA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		5 / 12 GLY A 127
LEU A  66
SER A 125
ALA A 126
SER A 181
 CO3  A 700 (-3.9A)
None
CO3  A 700 ( 4.5A)
CO3  A 700 (-3.4A)
None
 1.15A 1dfoC-1jnfA:
undetectable		 1dfoC-1jnfA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		5 / 12 GLY A 127
LEU A  66
SER A 125
ALA A 126
SER A 181
 CO3  A 700 (-3.9A)
None
CO3  A 700 ( 4.5A)
CO3  A 700 (-3.4A)
None
 1.16A 1eqbD-1jnfA:
undetectable		 1eqbD-1jnfA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI3_A_PE2A1_1
(THYMIDINE KINASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		5 / 12 HIS A 582
TYR A 412
GLN A 537
TYR A 514
GLU A 410
 FE  A 703 ( 3.3A)
None
None
CO3  A 701 ( 3.8A)
None
 1.30A 1ki3A-1jnfA:
0.0		 1ki3A-1jnfA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		4 / 6 TYR A  85
ASN A 292
TYR A  95
TYR A 188
 None
CL  A 800 ( 4.6A)
FE  A 702 ( 4.2A)
CO3  A 700 (-4.0A)
 1.44A 1kiaA-1jnfA:
0.6		 1kiaA-1jnfA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_ACTB1294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		4 / 6 TYR A  85
ASN A 292
TYR A  95
TYR A 188
 None
CL  A 800 ( 4.6A)
FE  A 702 ( 4.2A)
CO3  A 700 (-4.0A)
 1.45A 1kiaB-1jnfA:
0.6		 1kiaB-1jnfA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_ACTC2294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		4 / 7 TYR A  85
ASN A 292
TYR A  95
TYR A 188
 None
CL  A 800 ( 4.6A)
FE  A 702 ( 4.2A)
CO3  A 700 (-4.0A)
 1.44A 1kiaC-1jnfA:
0.5		 1kiaC-1jnfA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_ACTD3294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		4 / 7 TYR A  85
ASN A 292
TYR A  95
TYR A 188
 None
CL  A 800 ( 4.6A)
FE  A 702 ( 4.2A)
CO3  A 700 (-4.0A)
 1.44A 1kiaD-1jnfA:
undetectable		 1kiaD-1jnfA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		5 / 12 LEU A 426
LEU A 576
PHE A 479
LEU A 558
HIS A 450
 None
 1.33A 1kt5A-1jnfA:
0.0		 1kt5A-1jnfA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		3 / 3 PHE A 518
TRP A 547
GLU A 545
 None
 1.10A 1mogA-1jnfA:
0.3		 1mogA-1jnfA:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		4 / 6 TYR A  85
ASN A 292
TYR A  95
TYR A 188
 None
CL  A 800 ( 4.6A)
FE  A 702 ( 4.2A)
CO3  A 700 (-4.0A)
 1.45A 1nbhA-1jnfA:
0.5		 1nbhA-1jnfA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_ACTB1294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		4 / 7 TYR A  85
ASN A 292
TYR A  95
TYR A 188
 None
CL  A 800 ( 4.6A)
FE  A 702 ( 4.2A)
CO3  A 700 (-4.0A)
 1.44A 1nbhB-1jnfA:
0.4		 1nbhB-1jnfA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_ACTC2294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		4 / 6 TYR A  85
ASN A 292
TYR A  95
TYR A 188
 None
CL  A 800 ( 4.6A)
FE  A 702 ( 4.2A)
CO3  A 700 (-4.0A)
 1.46A 1nbhC-1jnfA:
0.4		 1nbhC-1jnfA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_ACTD3294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		4 / 7 TYR A  85
ASN A 292
TYR A  95
TYR A 188
 None
CL  A 800 ( 4.6A)
FE  A 702 ( 4.2A)
CO3  A 700 (-4.0A)
 1.45A 1nbhD-1jnfA:
0.4		 1nbhD-1jnfA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		5 / 12 LEU A  77
ASN A  76
GLY A  71
LEU A  62
LEU A  46
 None
 1.37A 1nhzA-1jnfA:
undetectable		 1nhzA-1jnfA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		5 / 11 MET A 463
ARG A 469
GLY A 445
GLU A 444
HIS A 450
 None
 1.37A 1vhwC-1jnfA:
undetectable
1vhwE-1jnfA:
undetectable		 1vhwC-1jnfA:
15.53
1vhwE-1jnfA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		5 / 11 HIS A 450
MET A 463
ARG A 469
GLY A 445
GLU A 444
 None
 1.37A 1vhwA-1jnfA:
undetectable
1vhwD-1jnfA:
undetectable		 1vhwA-1jnfA:
15.53
1vhwD-1jnfA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		5 / 9 PHE A 628
LEU A 599
PHE A 619
MET A 618
LEU A 408
 None
 1.33A 1wrkA-1jnfA:
undetectable
1wrkB-1jnfA:
0.0		 1wrkA-1jnfA:
10.96
1wrkB-1jnfA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		4 / 7 LEU A 576
PRO A 462
GLY A 394
ASP A 392
 None
None
None
FE  A 703 ( 3.0A)
 1.05A 2ddwB-1jnfA:
undetectable		 2ddwB-1jnfA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_C_GBNC1414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		5 / 8 TYR A 425
GLY A 513
GLY A 458
THR A 456
ALA A 457
 FE  A 703 ( 4.1A)
None
CO3  A 701 (-4.0A)
CO3  A 701 (-4.2A)
CO3  A 701 (-3.5A)
 1.27A 2ej3C-1jnfA:
undetectable		 2ej3C-1jnfA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		4 / 7 SER A 117
SER A 157
VAL A 159
LEU A 326
 None
 0.93A 2hdnE-1jnfA:
undetectable
2hdnF-1jnfA:
undetectable
2hdnH-1jnfA:
undetectable		 2hdnE-1jnfA:
4.55
2hdnF-1jnfA:
19.36
2hdnH-1jnfA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		4 / 7 SER A 157
VAL A 159
LEU A 326
SER A 117
 None
 0.89A 2hdnF-1jnfA:
undetectable
2hdnG-1jnfA:
0.0
2hdnH-1jnfA:
undetectable		 2hdnF-1jnfA:
19.36
2hdnG-1jnfA:
4.55
2hdnH-1jnfA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_B_CHDB701_0
(FERROCHELATASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		3 / 3 LYS A 524
GLY A 499
PRO A 500
 None
 0.93A 2hreB-1jnfA:
0.6		 2hreB-1jnfA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		3 / 3 THR A 534
ASP A 392
SER A 390
 None
FE  A 703 ( 3.0A)
None
 0.85A 2nxeA-1jnfA:
undetectable		 2nxeA-1jnfA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		3 / 3 THR A 534
ASP A 392
SER A 390
 None
FE  A 703 ( 3.0A)
None
 0.83A 2nxeB-1jnfA:
undetectable		 2nxeB-1jnfA:
17.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		3 / 3 LEU A 638
TYR A 647
GLY A 649
 None
 0.48A 2ocuA-1jnfA:
50.2		 2ocuA-1jnfA:
31.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		5 / 12 ASP A 589
THR A 321
ILE A 330
GLU A 338
PRO A 332
 None
 1.05A 2yzqA-1jnfA:
0.0		 2yzqA-1jnfA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		4 / 7 ALA A 583
ASN A 581
PRO A 421
ALA A 409
 None
 1.10A 2zgwA-1jnfA:
0.0		 2zgwA-1jnfA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		4 / 6 ALA A 583
ASN A 581
PRO A 421
ALA A 409
 None
 1.11A 2zgwB-1jnfA:
undetectable		 2zgwB-1jnfA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		3 / 3 TYR A 319
TYR A  95
GLY A  65
 None
FE  A 702 ( 4.2A)
None
 0.54A 3eteB-1jnfA:
undetectable
3eteD-1jnfA:
undetectable
3eteF-1jnfA:
undetectable		 3eteB-1jnfA:
21.51
3eteD-1jnfA:
21.51
3eteF-1jnfA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		3 / 3 TYR A 652
TYR A 425
GLY A 393
 None
FE  A 703 ( 4.1A)
None
 0.72A 3eteB-1jnfA:
undetectable
3eteD-1jnfA:
undetectable
3eteF-1jnfA:
undetectable		 3eteB-1jnfA:
21.51
3eteD-1jnfA:
21.51
3eteF-1jnfA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		3 / 3 TYR A 652
TYR A 425
GLY A 394
 None
FE  A 703 ( 4.1A)
None
 0.67A 3eteB-1jnfA:
undetectable
3eteD-1jnfA:
undetectable
3eteF-1jnfA:
undetectable		 3eteB-1jnfA:
21.51
3eteD-1jnfA:
21.51
3eteF-1jnfA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		5 / 12 TYR A 395
ILE A 461
GLY A 458
ALA A 452
ALA A 528
 None
None
CO3  A 701 (-4.0A)
None
None
 1.06A 3jayA-1jnfA:
0.0		 3jayA-1jnfA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3O_A_DLUA399_1
(PFV INTEGRASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		4 / 7 ASP A 163
ASP A 166
PRO A 168
GLN A 169
 None
 1.29A 3s3oA-1jnfA:
undetectable		 3s3oA-1jnfA:
21.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		5 / 7 GLY A 424
PRO A 580
ASN A 581
TYR A 647
GLY A 649
 None
 0.40A 3tajA-1jnfA:
50.4		 3tajA-1jnfA:
31.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		4 / 5 GLY A 424
PRO A 580
ASN A 581
TYR A 647
 None
 0.42A 3u8qA-1jnfA:
50.4		 3u8qA-1jnfA:
30.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_A_UEGA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		5 / 11 GLY A 123
ASP A  63
ALA A  64
GLY A  65
VAL A 323
 None
FE  A 702 ( 3.1A)
None
None
None
 1.31A 4c5lA-1jnfA:
undetectable		 4c5lA-1jnfA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		5 / 10 GLY A 123
ASP A  63
ALA A  64
GLY A  65
VAL A 323
 None
FE  A 702 ( 3.1A)
None
None
None
 1.31A 4c5lD-1jnfA:
undetectable		 4c5lD-1jnfA:
17.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		4 / 6 GLY A 424
PRO A 580
GLY A 649
TYR A 652
 None
 0.59A 4dxuA-1jnfA:
50.0		 4dxuA-1jnfA:
30.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7B_C_ACTC513_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		3 / 3 TYR A  96
HIS A 242
ARG A 245
 None
 1.17A 4e7bC-1jnfA:
0.1		 4e7bC-1jnfA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EVR_A_BEZA401_0
(PUTATIVE ABC
TRANSPORTER SUBUNIT,
SUBSTRATE-BINDING
COMPONENT)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		5 / 11 TYR A 514
VAL A 530
SER A 427
TYR A 425
ALA A 579
 CO3  A 701 ( 3.8A)
None
None
FE  A 703 ( 4.1A)
None
 1.19A 4evrA-1jnfA:
1.0		 4evrA-1jnfA:
19.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		5 / 9 GLU A 413
GLY A 424
PRO A 580
TYR A 647
TYR A 652
 None
 1.21A 4fimA-1jnfA:
50.2		 4fimA-1jnfA:
30.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		5 / 9 GLY A 424
PRO A 580
TYR A 647
GLY A 649
TYR A 652
 None
 0.49A 4fimA-1jnfA:
50.2		 4fimA-1jnfA:
30.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		5 / 6 GLY A 424
PRO A 580
ASN A 581
TYR A 647
GLY A 649
 None
 0.46A 4fjpA-1jnfA:
50.2		 4fjpA-1jnfA:
30.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		5 / 7 GLY A 424
PRO A 580
ASN A 581
TYR A 647
GLY A 649
 None
 0.46A 4forA-1jnfA:
50.2		 4forA-1jnfA:
30.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		3 / 3 PRO A 247
TYR A 314
GLY A 316
 None
 0.41A 4g2zA-1jnfA:
50.3		 4g2zA-1jnfA:
30.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		3 / 3 PRO A 580
TYR A 647
GLY A 649
 None
 0.38A 4g2zA-1jnfA:
50.3		 4g2zA-1jnfA:
30.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		6 / 7 ILE A 130
LEU A 134
HIS A 242
ALA A 244
TYR A 319
ALA A 322
 None
 0.53A 4g77A-1jnfA:
50.5		 4g77A-1jnfA:
31.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		6 / 7 ILE A 461
LEU A 465
HIS A 575
ALA A 577
TYR A 652
ALA A 655
 None
 0.56A 4g77A-1jnfA:
50.5		 4g77A-1jnfA:
31.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		4 / 8 PHE A 153
VAL A 202
ASP A 201
ALA A  99
 None
 0.85A 4m48A-1jnfA:
0.0		 4m48A-1jnfA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		4 / 8 PHE A 478
VAL A 527
ASP A 526
ALA A 429
 None
 0.89A 4m48A-1jnfA:
0.0		 4m48A-1jnfA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		4 / 5 LEU A  66
ALA A  64
LEU A  62
VAL A 246
 None
 1.13A 5cr1A-1jnfA:
undetectable		 5cr1A-1jnfA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		3 / 3 ASP A 392
ASN A 581
PHE A 529
 FE  A 703 ( 3.0A)
None
None
 0.83A 5jglB-1jnfA:
undetectable		 5jglB-1jnfA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		5 / 9 LEU A 293
ASP A 297
SER A 189
GLY A 187
PHE A 186
 None
None
None
CL  A 800 (-3.5A)
None
 1.16A 6ebpA-1jnfA:
undetectable		 6ebpA-1jnfA:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		5 / 10 LEU A 293
ASP A 297
SER A 189
GLY A 187
PHE A 186
 None
None
None
CL  A 800 (-3.5A)
None
 1.17A 6ebpB-1jnfA:
undetectable		 6ebpB-1jnfA:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		5 / 10 LEU A 293
ASP A 297
SER A 189
GLY A 187
PHE A 186
 None
None
None
CL  A 800 (-3.5A)
None
 1.13A 6ebpC-1jnfA:
undetectable		 6ebpC-1jnfA:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		4 / 6 ASP A 138
ASN A 230
LEU A 226
PHE A 204
 None
 1.25A 6ekuA-1jnfA:
0.0		 6ekuA-1jnfA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		3 / 3 LEU A  72
ASN A 129
LEU A 315
 None
 0.73A 6exiD-1jnfA:
1.0		 6exiD-1jnfA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		4 / 7 ASP A 625
ARG A 629
GLU A 410
GLU A 413
 None
 1.24A 6mn5B-1jnfA:
0.0		 6mn5B-1jnfA:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 1jnf SEROTRANSFERRIN
(Oryctolagus
cuniculus) 		3 / 3 ASP A  63
LEU A  66
ARG A 327
 FE  A 702 ( 3.1A)
None
None
 0.70A 7dfrA-1jnfA:
undetectable		 7dfrA-1jnfA:
14.50