SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jny'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDW_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 10 VAL A 313
LEU A 259
PRO A 250
PHE A 267
GLU A 275
 None
 1.32A 1fdwA-1jnyA:
4.6		 1fdwA-1jnyA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_A_CCSA417_0
(ESTROGEN RECEPTOR)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		3 / 3 GLU A 360
LYS A 375
VAL A 362
 None
 0.92A 1l2iA-1jnyA:
0.0		 1l2iA-1jnyA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_1
(DIPEPTIDYL PEPTIDASE
IV)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 12 TYR A 218
VAL A 151
TYR A 166
TYR A 210
VAL A 170
 None
 1.41A 1x70A-1jnyA:
2.9		 1x70A-1jnyA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A15_A_NCAA1001_0
(HYPOTHETICAL PROTEIN
RV0760C)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 11 VAL A  11
ILE A  88
LEU A   9
LEU A 215
LEU A 219
 None
 1.23A 2a15A-1jnyA:
0.0		 2a15A-1jnyA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		4 / 7 ILE A 307
ILE A 295
LEU A 259
ILE A 235
 None
 0.79A 2q83A-1jnyA:
undetectable		 2q83A-1jnyA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 11 TYR A 218
VAL A 151
TYR A 166
TYR A 210
VAL A 170
 None
 1.45A 2rguB-1jnyA:
undetectable		 2rguB-1jnyA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_B_C2FB401_0
(AMINOMETHYLTRANSFERA
SE)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 12 TYR A 166
ILE A 169
TYR A 122
VAL A 173
TRP A 209
 None
 1.43A 3a8iB-1jnyA:
2.0		 3a8iB-1jnyA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_C_C2FC401_0
(AMINOMETHYLTRANSFERA
SE)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 12 TYR A 166
ILE A 169
TYR A 122
VAL A 173
TRP A 209
 None
 1.48A 3a8iC-1jnyA:
0.7		 3a8iC-1jnyA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_B_VDNB1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 11 ILE A 148
LEU A   9
ALA A 108
ILE A  10
ILE A 136
 None
 1.16A 3b2rB-1jnyA:
undetectable		 3b2rB-1jnyA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 12 TYR A 218
VAL A 151
TYR A 166
TYR A 210
VAL A 170
 None
 1.44A 3bjmA-1jnyA:
undetectable		 3bjmA-1jnyA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 12 TYR A 218
VAL A 151
TYR A 166
TYR A 210
VAL A 170
 None
 1.41A 3g0bA-1jnyA:
2.2		 3g0bA-1jnyA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 12 TYR A 218
VAL A 151
TYR A 166
TYR A 210
VAL A 170
 None
 1.41A 3g0bB-1jnyA:
undetectable		 3g0bB-1jnyA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 12 TYR A 218
VAL A 151
TYR A 166
TYR A 210
VAL A 170
 None
 1.40A 3g0bC-1jnyA:
undetectable		 3g0bC-1jnyA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 12 TYR A 218
VAL A 151
TYR A 166
TYR A 210
VAL A 170
 None
 1.39A 3g0bD-1jnyA:
2.7		 3g0bD-1jnyA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 12 LEU A 222
ALA A 108
LEU A 215
PHE A  79
LEU A  27
 None
 1.38A 3vw1B-1jnyA:
0.0		 3vw1B-1jnyA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 12 TYR A 218
VAL A 151
TYR A 166
TYR A 210
VAL A 170
 None
 1.41A 3w2tA-1jnyA:
2.9		 3w2tA-1jnyA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 12 TYR A 218
VAL A 151
TYR A 166
TYR A 210
VAL A 170
 None
 1.39A 3w2tB-1jnyA:
2.1		 3w2tB-1jnyA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		4 / 5 PHE A 297
PHE A 267
ILE A 265
GLY A 274
 None
 0.94A 4ejjC-1jnyA:
0.0		 4ejjC-1jnyA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOS_A_4KOA201_1
(UNCHARACTERIZED
PROTEIN)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 12 PRO A 195
GLY A  18
ASN A 152
PHE A  55
LEU A  59
 GDP  A 500 (-4.3A)
GDP  A 500 (-3.2A)
GDP  A 500 (-3.2A)
None
None
 1.46A 4kosA-1jnyA:
undetectable		 4kosA-1jnyA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 12 PRO A 195
GLY A  18
ASN A 152
PHE A  55
LEU A  59
 GDP  A 500 (-4.3A)
GDP  A 500 (-3.2A)
GDP  A 500 (-3.2A)
None
None
 1.48A 4kotA-1jnyA:
undetectable		 4kotA-1jnyA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A206_1
(UNCHARACTERIZED
PROTEIN)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 10 PRO A 195
GLY A  18
ASN A 152
PHE A  55
LEU A  59
 GDP  A 500 (-4.3A)
GDP  A 500 (-3.2A)
GDP  A 500 (-3.2A)
None
None
 1.43A 4kouA-1jnyA:
undetectable		 4kouA-1jnyA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 12 PRO A 195
GLY A  18
ASN A 152
PHE A  55
LEU A  59
 GDP  A 500 (-4.3A)
GDP  A 500 (-3.2A)
GDP  A 500 (-3.2A)
None
None
 1.46A 4kovA-1jnyA:
0.0		 4kovA-1jnyA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOW_A_CFXA204_1
(UNCHARACTERIZED
PROTEIN)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 12 PRO A 195
GLY A  18
ASN A 152
PHE A  55
LEU A  59
 GDP  A 500 (-4.3A)
GDP  A 500 (-3.2A)
GDP  A 500 (-3.2A)
None
None
 1.47A 4kowA-1jnyA:
undetectable		 4kowA-1jnyA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOX_A_CLSA205_1
(UNCHARACTERIZED
PROTEIN)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 11 PRO A 195
GLY A  18
ASN A 152
PHE A  55
LEU A  59
 GDP  A 500 (-4.3A)
GDP  A 500 (-3.2A)
GDP  A 500 (-3.2A)
None
None
 1.47A 4koxA-1jnyA:
0.0		 4koxA-1jnyA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		4 / 5 PRO A 269
GLY A 271
ASP A 239
ASP A 306
 None
 1.11A 4n48B-1jnyA:
undetectable		 4n48B-1jnyA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_2
(PROTEASE)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 12 GLY A 422
ASP A 414
GLY A 420
ILE A 330
VAL A 349
 None
 0.90A 4q5mA-1jnyA:
undetectable		 4q5mA-1jnyA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 8 LEU A  22
ALA A 150
LEU A 215
LEU A 219
LEU A   9
 None
 1.05A 4z90A-1jnyA:
undetectable
4z90B-1jnyA:
undetectable
4z90C-1jnyA:
undetectable
4z90D-1jnyA:
undetectable
4z90E-1jnyA:
undetectable		 4z90A-1jnyA:
21.35
4z90B-1jnyA:
21.35
4z90C-1jnyA:
21.35
4z90D-1jnyA:
21.35
4z90E-1jnyA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 12 ASP A 311
GLY A 271
GLY A 314
LEU A 233
GLY A 301
 None
 0.89A 5i73A-1jnyA:
undetectable		 5i73A-1jnyA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		4 / 6 PHE A 189
VAL A 149
MET A 126
ILE A 136
 None
 1.05A 5iwuA-1jnyA:
0.0		 5iwuA-1jnyA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMF_A_6U9A1301_1
(ION TRANSPORT
PROTEIN)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		4 / 6 GLY A 296
GLU A 280
PHE A 297
TYR A 241
 None
 0.95A 5kmfA-1jnyA:
undetectable
5kmfC-1jnyA:
undetectable		 5kmfA-1jnyA:
21.54
5kmfC-1jnyA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 12 TYR A 218
VAL A 151
TYR A 166
TYR A 210
VAL A 170
 None
 1.41A 6b1eB-1jnyA:
undetectable		 6b1eB-1jnyA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 1jny ELONGATION FACTOR
1-ALPHA
(Sulfolobus
solfataricus) 		5 / 11 MET A 177
TYR A 122
VAL A 115
GLY A  13
ALA A  91
 None
 1.32A 6hu9A-1jnyA:
0.0
6hu9E-1jnyA:
undetectable
6hu9I-1jnyA:
0.0		 6hu9A-1jnyA:
22.06
6hu9E-1jnyA:
19.22
6hu9I-1jnyA:
9.93