SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jo0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1jo0 HYPOTHETICAL PROTEIN
HI1333
(Haemophilus
influenzae) 		3 / 3 ILE A  48
ILE A  67
LEU A  96
 None
 0.54A 2prgA-1jo0A:
undetectable		 2prgA-1jo0A:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1jo0 HYPOTHETICAL PROTEIN
HI1333
(Haemophilus
influenzae) 		4 / 4 LEU A  25
GLY A  26
GLY A  29
THR A  31
 None
 0.58A 3si7A-1jo0A:
undetectable		 3si7A-1jo0A:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB202_0
(HYDROXYNITRILE LYASE)		 1jo0 HYPOTHETICAL PROTEIN
HI1333
(Haemophilus
influenzae) 		4 / 7 VAL A  50
LEU A  42
VAL A  68
THR A  71
 None
None
GOL  A 103 (-4.5A)
None
 1.04A 5e4dA-1jo0A:
undetectable
5e4dB-1jo0A:
undetectable		 5e4dA-1jo0A:
17.59
5e4dB-1jo0A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6L_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1jo0 HYPOTHETICAL PROTEIN
HI1333
(Haemophilus
influenzae) 		5 / 9 ILE A  64
ALA A  66
LEU A  25
ILE A  48
PRO A  21
 None
None
None
None
GOL  A 100 (-4.3A)
 1.44A 5z6lA-1jo0A:
undetectable		 5z6lA-1jo0A:
21.60