SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1joe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LP9_D_SPMD230_1 (LS-24)	1joe	AUTOINDUCER-2 PRODUCTION PROTEIN (Haemophilus influenzae)	3 / 3	GLU A 46 GLU A 141 ASN A 145	HG A 201 ( 4.3A) None None	0.87A	3lp9B-1joeA: 0.6 3lp9D-1joeA: 0.4	3lp9B-1joeA: 21.12 3lp9D-1joeA: 21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W6H_A_AZMA303_1 (CARBONIC ANHYDRASE 1)	1joe	AUTOINDUCER-2 PRODUCTION PROTEIN (Haemophilus influenzae)	4 / 8	GLN A 117 HIS A 134 HIS A 54 HIS A 58	None None ZN A 205 (-3.3A) ZN A 205 (-3.4A)	1.05A	3w6hA-1joeA: undetectable	3w6hA-1joeA: 20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XI3_D_29SD601_2 (ESTROGEN RECEPTOR)	1joe	AUTOINDUCER-2 PRODUCTION PROTEIN (Haemophilus influenzae)	3 / 3	LEU A 68 ASP A 66 ILE A 92	None	0.65A	4xi3D-1joeA: undetectable	4xi3D-1joeA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZRD_A_CUA607_0 (TYROSINASE)	1joe	AUTOINDUCER-2 PRODUCTION PROTEIN (Haemophilus influenzae)	3 / 3	HIS A 54 HIS A 134 HIS A 58	ZN A 205 (-3.3A) None ZN A 205 (-3.4A)	0.50A	5zrdA-1joeA: undetectable	5zrdA-1joeA: 15.81

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3LP9_D_SPMD230_1","LS-24;LS-24","1joe","AUTOINDUCER-2 PRODUCTION PROTEIN","Haemophilus influenzae",3,"GLU A  46;GLU A 141;ASN A 145"," HG A 201 ( 4.3A);None;None","0.87A","3lp9B-1joeA:0.6;3lp9D-1joeA:0.4","3lp9B-1joeA:21.12;3lp9D-1joeA:21.12"],["3W6H_A_AZMA303_1","CARBONIC ANHYDRASE 1","1joe","AUTOINDUCER-2 PRODUCTION PROTEIN","Haemophilus influenzae",4,"GLN A 117;HIS A 134;HIS A  54;HIS A  58","None;None; ZN A 205 (-3.3A); ZN A 205 (-3.4A)","1.05A","3w6hA-1joeA:undetectable","3w6hA-1joeA:20.23"],["4XI3_D_29SD601_2","ESTROGEN RECEPTOR","1joe","AUTOINDUCER-2 PRODUCTION PROTEIN","Haemophilus influenzae",3,"LEU A  68;ASP A  66;ILE A  92","None","0.65A","4xi3D-1joeA:undetectable","4xi3D-1joeA:22.22"],["5ZRD_A_CUA607_0","TYROSINASE","1joe","AUTOINDUCER-2 PRODUCTION PROTEIN","Haemophilus influenzae",3,"HIS A  54;HIS A 134;HIS A  58"," ZN A 205 (-3.3A);None; ZN A 205 (-3.4A)","0.50A","5zrdA-1joeA:undetectable","5zrdA-1joeA:15.81"]]