SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jov'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA256_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)		 1jov HI1317
(Haemophilus
influenzae) 		4 / 7 VAL A  16
LEU A   5
THR A   8
LEU A   9
 None
 0.88A 1jgsA-1jovA:
0.0		 1jgsA-1jovA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)		 1jov HI1317
(Haemophilus
influenzae) 		4 / 8 ALA A  68
ILE A  93
ASN A  67
PRO A  86
 None
 0.88A 3fxrA-1jovA:
undetectable		 3fxrA-1jovA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 1jov HI1317
(Haemophilus
influenzae) 		4 / 5 HIS A 218
SER A 263
THR A 136
GLU A 265
 None
 1.29A 3tm4A-1jovA:
undetectable		 3tm4A-1jovA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 1jov HI1317
(Haemophilus
influenzae) 		4 / 5 HIS A 218
SER A 263
THR A 136
GLU A 265
 None
 1.27A 3tm4B-1jovA:
undetectable		 3tm4B-1jovA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_A_CLMA221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1jov HI1317
(Haemophilus
influenzae) 		4 / 4 PHE A  80
ALA A 148
CYH A  76
HIS A  88
 None
None
None
SO4  A 280 ( 4.7A)
 1.04A 3u9fB-1jovA:
0.0		 3u9fB-1jovA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1jov HI1317
(Haemophilus
influenzae) 		3 / 3 PHE A  80
CYH A  76
HIS A  88
 None
None
SO4  A 280 ( 4.7A)
 0.95A 3u9fF-1jovA:
0.0		 3u9fF-1jovA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1jov HI1317
(Haemophilus
influenzae) 		3 / 3 PHE A  80
CYH A  76
HIS A  88
 None
None
SO4  A 280 ( 4.7A)
 0.96A 3u9fG-1jovA:
0.0		 3u9fG-1jovA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1jov HI1317
(Haemophilus
influenzae) 		3 / 3 PHE A  80
CYH A  76
HIS A  88
 None
None
SO4  A 280 ( 4.7A)
 0.94A 3u9fL-1jovA:
0.0		 3u9fL-1jovA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_P_CLMP221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1jov HI1317
(Haemophilus
influenzae) 		4 / 4 PHE A  80
ALA A 148
CYH A  76
HIS A  88
 None
None
None
SO4  A 280 ( 4.7A)
 1.06A 3u9fR-1jovA:
0.0		 3u9fR-1jovA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1jov HI1317
(Haemophilus
influenzae) 		3 / 3 PHE A  80
CYH A  76
HIS A  88
 None
None
SO4  A 280 ( 4.7A)
 0.88A 3u9fS-1jovA:
0.0		 3u9fS-1jovA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1jov HI1317
(Haemophilus
influenzae) 		4 / 7 ILE A  75
HIS A 134
VAL A 108
PHE A 112
 None
 1.10A 4a97H-1jovA:
undetectable		 4a97H-1jovA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1jov HI1317
(Haemophilus
influenzae) 		4 / 8 ASN A 227
GLU A 189
ILE A 187
ASN A 159
 None
 0.96A 4d33A-1jovA:
undetectable		 4d33A-1jovA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1jov HI1317
(Haemophilus
influenzae) 		4 / 7 ASN A 227
GLU A 189
ILE A 187
ASN A 159
 None
 1.03A 4d33B-1jovA:
undetectable		 4d33B-1jovA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1jov HI1317
(Haemophilus
influenzae) 		4 / 8 ASN A 227
GLU A 189
ILE A 187
ASN A 159
 None
 1.07A 4d39A-1jovA:
undetectable		 4d39A-1jovA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1jov HI1317
(Haemophilus
influenzae) 		4 / 7 ASN A 227
GLU A 189
ILE A 187
ASN A 159
 None
 1.08A 4d39B-1jovA:
undetectable		 4d39B-1jovA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ8_A_ASDA602_1
(CYTOCHROME P450 19A1)		 1jov HI1317
(Haemophilus
influenzae) 		5 / 10 ILE A  75
ALA A 148
THR A 249
VAL A 264
MET A 127
 None
 1.49A 4kq8A-1jovA:
undetectable		 4kq8A-1jovA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_2
(ESTROGEN RECEPTOR)		 1jov HI1317
(Haemophilus
influenzae) 		4 / 5 LEU A   6
LEU A   9
LEU A  37
HIS A  25
 None
 0.97A 5gtrA-1jovA:
undetectable		 5gtrA-1jovA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AY6_A_VORA501_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 1jov HI1317
(Haemophilus
influenzae) 		5 / 9 ALA A  40
THR A 151
LEU A  55
CYH A 133
LEU A  57
 None
 1.48A 6ay6A-1jovA:
undetectable		 6ay6A-1jovA:
20.13