SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jpd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3001_1
(SERUM ALBUMIN)		 1jpd L-ALA-D/L-GLU
EPIMERASE
(Escherichia
coli) 		6 / 11 TYR X  51
LEU X 237
ARG X 240
HIS X 229
ARG X  50
ALA X 207
 None
 1.46A 1hk1A-1jpdX:
undetectable		 1hk1A-1jpdX:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3001_1
(SERUM ALBUMIN)		 1jpd L-ALA-D/L-GLU
EPIMERASE
(Escherichia
coli) 		5 / 9 TYR X  51
LEU X 237
HIS X 229
ARG X  50
ALA X 207
 None
 1.43A 1hk2A-1jpdX:
0.0		 1hk2A-1jpdX:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3001_1
(SERUM ALBUMIN)		 1jpd L-ALA-D/L-GLU
EPIMERASE
(Escherichia
coli) 		6 / 11 TYR X  51
LEU X 237
ARG X 240
HIS X 229
ARG X  50
ALA X 207
 None
 1.47A 1hk3A-1jpdX:
undetectable		 1hk3A-1jpdX:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1jpd L-ALA-D/L-GLU
EPIMERASE
(Escherichia
coli) 		3 / 3 GLU X 214
GLU X 242
LEU X 234
 None
 0.78A 1v8bB-1jpdX:
3.3		 1v8bB-1jpdX:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B8J_A_SPMA653_1
(CLASS B ACID
PHOSPHATASE)		 1jpd L-ALA-D/L-GLU
EPIMERASE
(Escherichia
coli) 		5 / 9 ASP X 249
TRP X  11
GLY X 252
ASP X  92
THR X 279
 None
 1.30A 2b8jA-1jpdX:
0.5		 2b8jA-1jpdX:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 1jpd L-ALA-D/L-GLU
EPIMERASE
(Escherichia
coli) 		4 / 6 THR X 118
THR X 121
THR X 172
ASP X 170
 None
 1.00A 2okcB-1jpdX:
undetectable		 2okcB-1jpdX:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1jpd L-ALA-D/L-GLU
EPIMERASE
(Escherichia
coli) 		3 / 3 LEU X 115
PRO X 116
LEU X 321
 None
 0.50A 3hcrA-1jpdX:
3.2		 3hcrA-1jpdX:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		 1jpd L-ALA-D/L-GLU
EPIMERASE
(Escherichia
coli) 		4 / 8 SER X 280
CYH X 275
LEU X 298
ASP X 299
 None
 1.03A 3m0wE-1jpdX:
undetectable
3m0wF-1jpdX:
undetectable
3m0wG-1jpdX:
undetectable
3m0wH-1jpdX:
undetectable		 3m0wE-1jpdX:
16.12
3m0wF-1jpdX:
16.12
3m0wG-1jpdX:
16.12
3m0wH-1jpdX:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 1jpd L-ALA-D/L-GLU
EPIMERASE
(Escherichia
coli) 		3 / 3 GLN X 123
THR X 124
LEU X 304
 None
 0.73A 3ondA-1jpdX:
3.3		 3ondA-1jpdX:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 1jpd L-ALA-D/L-GLU
EPIMERASE
(Escherichia
coli) 		3 / 3 GLN X 123
THR X 124
LEU X 304
 None
 0.71A 3ondB-1jpdX:
3.3		 3ondB-1jpdX:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_C_FLRC700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1jpd L-ALA-D/L-GLU
EPIMERASE
(Escherichia
coli) 		5 / 12 LEU X  69
LEU X  82
VAL X  32
GLY X  43
ALA X  90
 None
 1.05A 3rr3C-1jpdX:
0.6		 3rr3C-1jpdX:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_D_FLRD700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1jpd L-ALA-D/L-GLU
EPIMERASE
(Escherichia
coli) 		5 / 12 LEU X  69
LEU X  82
VAL X  32
GLY X  43
ALA X  90
 None
 1.06A 3rr3D-1jpdX:
undetectable		 3rr3D-1jpdX:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1jpd L-ALA-D/L-GLU
EPIMERASE
(Escherichia
coli) 		3 / 3 PHE X 216
CYH X 190
HIS X 218
 None
 1.23A 3u9fG-1jpdX:
0.0		 3u9fG-1jpdX:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1jpd L-ALA-D/L-GLU
EPIMERASE
(Escherichia
coli) 		5 / 11 ALA X 199
LEU X 193
ALA X 194
VAL X 125
LEU X 147
 None
 1.14A 4nqaA-1jpdX:
undetectable		 4nqaA-1jpdX:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 1jpd L-ALA-D/L-GLU
EPIMERASE
(Escherichia
coli) 		4 / 5 GLY X 317
PRO X 301
THR X 121
THR X 315
 None
 1.22A 5h5fA-1jpdX:
1.8		 5h5fA-1jpdX:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1jpd L-ALA-D/L-GLU
EPIMERASE
(Escherichia
coli) 		3 / 3 ASP X 225
ASN X 245
ASP X 297
 None
 0.83A 5vopA-1jpdX:
5.4		 5vopA-1jpdX:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1jpd L-ALA-D/L-GLU
EPIMERASE
(Escherichia
coli) 		3 / 3 ASP X 225
ASN X 245
ASP X 297
 None
 0.81A 5vopB-1jpdX:
8.3		 5vopB-1jpdX:
23.17