SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jpe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G72_A_SAMA2001_1 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	1jpe	DSBD-ALPHA (Escherichia coli)	4 / 6	TYR A 71 TYR A 42 GLY A 72 TYR A 40	None	1.29A	2g72A-1jpeA: undetectable	2g72A-1jpeA: 18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KW2_A_ADNA300_1 (PROBABLE R-RNA METHYLTRANSFERASE)	1jpe	DSBD-ALPHA (Escherichia coli)	5 / 11	ALA A 53 VAL A 122 ILE A 55 LEU A 119 THR A 86	None	0.87A	3kw2A-1jpeA: 0.2	3kw2A-1jpeA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DPR_A_X8ZA702_1 (LEUKOTRIENE A-4 HYDROLASE)	1jpe	DSBD-ALPHA (Escherichia coli)	5 / 9	TYR A 71 GLY A 72 GLU A 69 TYR A 42 TYR A 40	None	1.16A	4dprA-1jpeA: undetectable	4dprA-1jpeA: 13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E7B_C_ACTC513_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	1jpe	DSBD-ALPHA (Escherichia coli)	3 / 3	TYR A 40 HIS A 66 ARG A 78	None	0.96A	4e7bC-1jpeA: 0.0	4e7bC-1jpeA: 16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KC0_A_RBFA303_2 (RIBOFLAVIN TRANSPORTER RIBU)	1jpe	DSBD-ALPHA (Escherichia coli)	3 / 3	LYS A 115 LEU A 119 ILE A 48	None	0.66A	5kc0A-1jpeA: undetectable	5kc0A-1jpeA: 19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KC4_A_RBFA201_2 (RIBOFLAVIN TRANSPORTER RIBU)	1jpe	DSBD-ALPHA (Escherichia coli)	3 / 3	LYS A 115 LEU A 119 ILE A 48	None	0.72A	5kc4A-1jpeA: undetectable	5kc4A-1jpeA: 20.11

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2G72_A_SAMA2001_1","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","1jpe","DSBD-ALPHA","Escherichia coli",4,"TYR A  71;TYR A  42;GLY A  72;TYR A  40","None","1.29A","2g72A-1jpeA:undetectable","2g72A-1jpeA:18.93"],["3KW2_A_ADNA300_1","PROBABLE R-RNA METHYLTRANSFERASE","1jpe","DSBD-ALPHA","Escherichia coli",5,"ALA A  53;VAL A 122;ILE A  55;LEU A 119;THR A  86","None","0.87A","3kw2A-1jpeA:0.2","3kw2A-1jpeA:22.22"],["4DPR_A_X8ZA702_1","LEUKOTRIENE A-4 HYDROLASE","1jpe","DSBD-ALPHA","Escherichia coli",5,"TYR A  71;GLY A  72;GLU A  69;TYR A  42;TYR A  40","None","1.16A","4dprA-1jpeA:undetectable","4dprA-1jpeA:13.86"],["4E7B_C_ACTC513_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","1jpe","DSBD-ALPHA","Escherichia coli",3,"TYR A  40;HIS A  66;ARG A  78","None","0.96A","4e7bC-1jpeA:0.0","4e7bC-1jpeA:16.51"],["5KC0_A_RBFA303_2","RIBOFLAVIN TRANSPORTER RIBU","1jpe","DSBD-ALPHA","Escherichia coli",3,"LYS A 115;LEU A 119;ILE A  48","None","0.66A","5kc0A-1jpeA:undetectable","5kc0A-1jpeA:19.59"],["5KC4_A_RBFA201_2","RIBOFLAVIN TRANSPORTER RIBU","1jpe","DSBD-ALPHA","Escherichia coli",3,"LYS A 115;LEU A 119;ILE A  48","None","0.72A","5kc4A-1jpeA:undetectable","5kc4A-1jpeA:20.11"]]