SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jq4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)		 1jq4 METHANE
MONOOXYGENASE
COMPONENT C
(Methylococcus
capsulatus) 		4 / 7 LEU A  61
ARG A  83
GLY A  46
SER A  65
 None
None
FES  A  99 (-4.6A)
None
 0.93A 4cp3A-1jq4A:
0.0
4cp3B-1jq4A:
0.0		 4cp3A-1jq4A:
26.02
4cp3B-1jq4A:
26.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_D_EY4D500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1jq4 METHANE
MONOOXYGENASE
COMPONENT C
(Methylococcus
capsulatus) 		4 / 7 ILE A  92
PRO A  95
ALA A  30
THR A  29
 None
 0.93A 6cduC-1jq4A:
undetectable
6cduD-1jq4A:
undetectable		 6cduC-1jq4A:
14.15
6cduD-1jq4A:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1jq4 METHANE
MONOOXYGENASE
COMPONENT C
(Methylococcus
capsulatus) 		4 / 8 ILE A  92
PRO A  95
ALA A  30
THR A  29
 None
 0.92A 6cduD-1jq4A:
undetectable
6cduE-1jq4A:
undetectable		 6cduD-1jq4A:
14.15
6cduE-1jq4A:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1jq4 METHANE
MONOOXYGENASE
COMPONENT C
(Methylococcus
capsulatus) 		4 / 7 ALA A  30
THR A  29
ILE A  92
PRO A  95
 None
 0.91A 6cduF-1jq4A:
undetectable
6cduJ-1jq4A:
undetectable		 6cduF-1jq4A:
14.15
6cduJ-1jq4A:
14.15