SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jqi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE
(Rattus
norvegicus) 		4 / 8 ILE A 251
ASN A 164
GLY A 247
LEU A 244
 None
None
None
CAA  A 400 (-4.1A)
 0.99A 1dzmA-1jqiA:
undetectable		 1dzmA-1jqiA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE
(Rattus
norvegicus) 		5 / 12 TYR A  99
ILE A 239
GLY A 101
ALA A  57
GLY A 107
 None
 1.08A 1kiaA-1jqiA:
undetectable		 1kiaA-1jqiA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE
(Rattus
norvegicus) 		5 / 12 TYR A  99
ILE A 239
GLY A 101
ALA A  57
GLY A 107
 None
 1.09A 1kiaB-1jqiA:
undetectable		 1kiaB-1jqiA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE
(Rattus
norvegicus) 		5 / 12 TYR A  99
ILE A 239
GLY A 101
ALA A  57
GLY A 107
 None
 1.09A 1kiaC-1jqiA:
undetectable		 1kiaC-1jqiA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE
(Rattus
norvegicus) 		5 / 12 TYR A  99
ILE A 239
GLY A 101
ALA A  57
GLY A 107
 None
 1.09A 1nbhB-1jqiA:
undetectable		 1nbhB-1jqiA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE
(Rattus
norvegicus) 		4 / 7 LEU A  10
ILE A  76
ALA A 332
ILE A 258
 None
 0.81A 2xkwA-1jqiA:
0.0		 2xkwA-1jqiA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE
(Rattus
norvegicus) 		3 / 3 TYR A 367
VAL A  90
THR A 364
 CAA  A 400 (-3.8A)
None
None
 0.70A 2ygnA-1jqiA:
undetectable		 2ygnA-1jqiA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE
(Rattus
norvegicus) 		5 / 12 THR A 304
LEU A 256
GLY A  84
LEU A  29
ILE A 209
 None
 1.11A 3ijdA-1jqiA:
undetectable		 3ijdA-1jqiA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE
(Rattus
norvegicus) 		5 / 12 TYR A  74
LEU A  78
GLY A 250
SER A  97
LEU A  55
 None
 1.34A 3okxA-1jqiA:
0.0		 3okxA-1jqiA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE
(Rattus
norvegicus) 		4 / 7 LEU A  78
TYR A 367
THR A 364
ILE A 251
 None
CAA  A 400 (-3.8A)
None
None
 0.91A 3p50A-1jqiA:
2.4		 3p50A-1jqiA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE
(Rattus
norvegicus) 		4 / 7 LEU A  78
TYR A 367
THR A 364
ILE A 251
 None
CAA  A 400 (-3.8A)
None
None
 0.91A 3p50B-1jqiA:
2.4		 3p50B-1jqiA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE
(Rattus
norvegicus) 		4 / 7 LEU A  78
TYR A 367
THR A 364
ILE A 251
 None
CAA  A 400 (-3.8A)
None
None
 0.91A 3p50C-1jqiA:
3.2		 3p50C-1jqiA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_D_PFLD320_1
(GLR4197 PROTEIN)		 1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE
(Rattus
norvegicus) 		4 / 7 LEU A  78
TYR A 367
THR A 364
ILE A 251
 None
CAA  A 400 (-3.8A)
None
None
 0.91A 3p50D-1jqiA:
2.4		 3p50D-1jqiA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE
(Rattus
norvegicus) 		4 / 7 LEU A  78
TYR A 367
THR A 364
ILE A 251
 None
CAA  A 400 (-3.8A)
None
None
 0.91A 3p50E-1jqiA:
2.4		 3p50E-1jqiA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TPX_C_ACTC207_0
(E3 UBIQUITIN-PROTEIN
LIGASE MDM2)		 1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE
(Rattus
norvegicus) 		4 / 4 LYS A 315
PRO A 316
LEU A 310
ASN A 313
 None
 1.11A 3tpxC-1jqiA:
undetectable		 3tpxC-1jqiA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE
(Rattus
norvegicus) 		4 / 8 ASP A 360
ILE A 209
GLY A 208
SER A 131
 None
None
None
FAD  A 399 (-2.9A)
 0.87A 4acbB-1jqiA:
undetectable
4acbC-1jqiA:
undetectable		 4acbB-1jqiA:
20.81
4acbC-1jqiA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE
(Rattus
norvegicus) 		5 / 12 CYH A  21
ALA A  73
MET A  58
GLY A  68
LEU A  69
 None
 1.21A 4j7xB-1jqiA:
undetectable		 4j7xB-1jqiA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W9N_C_CCSC1548_0
(ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE)		 1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE
(Rattus
norvegicus) 		3 / 3 ALA A 146
TRP A 153
VAL A 154
 None
 0.36A 4w9nC-1jqiA:
0.0		 4w9nC-1jqiA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE
(Rattus
norvegicus) 		4 / 5 GLY A 247
SER A 321
GLU A 368
ASP A 245
 None
None
CAA  A 400 (-4.1A)
CAA  A 400 (-2.9A)
 1.19A 4xueA-1jqiA:
undetectable		 4xueA-1jqiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE
(Rattus
norvegicus) 		4 / 7 SER A 262
ALA A 332
THR A 364
ILE A 363
 None
None
None
FAD  A 399 (-4.7A)
 1.03A 5te8A-1jqiA:
0.0		 5te8A-1jqiA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE
(Rattus
norvegicus) 		4 / 7 SER A 262
ALA A 361
THR A 364
ILE A 251
 None
 0.87A 5te8A-1jqiA:
0.0		 5te8A-1jqiA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE
(Rattus
norvegicus) 		5 / 9 ALA A  33
ALA A  86
GLY A  84
SER A  87
GLY A  89
 None
 1.14A 6bklE-1jqiA:
undetectable
6bklF-1jqiA:
undetectable
6bklG-1jqiA:
undetectable
6bklH-1jqiA:
undetectable		 6bklE-1jqiA:
5.61
6bklF-1jqiA:
5.61
6bklG-1jqiA:
5.61
6bklH-1jqiA:
5.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_B_DZPB502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE
(Rattus
norvegicus) 		5 / 11 ILE A 116
LEU A 104
MET A  92
ASN A  95
LEU A  56
 None
 1.20A 6hupA-1jqiA:
4.4
6hupB-1jqiA:
4.4		 6hupA-1jqiA:
13.07
6hupB-1jqiA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 1jqi SHORT CHAIN ACYL-COA
DEHYDROGENASE
(Rattus
norvegicus) 		4 / 7 SER A 262
ALA A 361
THR A 364
ILE A 251
 None
 0.97A 6ma7A-1jqiA:
0.0		 6ma7A-1jqiA:
10.57