SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jr6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1jr6 HELICASE NS3
(Hepacivirus
C) 		4 / 8 LEU A  30
VAL A  32
VAL A  83
LEU A  51
 None
 0.88A 2zujA-1jr6A:
undetectable		 2zujA-1jr6A:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_1
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 1jr6 HELICASE NS3
(Hepacivirus
C) 		5 / 11 SER A  98
VAL A  82
LEU A  39
ALA A  84
VAL A  63
 None
 1.15A 4e0fA-1jr6A:
0.0		 4e0fA-1jr6A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1jr6 HELICASE NS3
(Hepacivirus
C) 		3 / 3 LEU A  88
ALA A  87
LEU A  39
 None
 0.47A 5uunB-1jr6A:
undetectable		 5uunB-1jr6A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA307_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 1jr6 HELICASE NS3
(Hepacivirus
C) 		4 / 5 ASP A 106
PRO A 135
GLU A 137
THR A 104
 None
 1.35A 5uxcA-1jr6A:
0.0		 5uxcA-1jr6A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1jr6 HELICASE NS3
(Hepacivirus
C) 		5 / 8 LEU A  15
VAL A  13
ILE A  10
GLY A 123
ILE A  40
 None
 1.19A 5vkqB-1jr6A:
undetectable
5vkqC-1jr6A:
undetectable		 5vkqB-1jr6A:
6.66
5vkqC-1jr6A:
6.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_0
(REGULATORY PROTEIN
TETR)		 1jr6 HELICASE NS3
(Hepacivirus
C) 		5 / 12 ALA A  53
LEU A  58
TYR A  24
VAL A  83
ASP A  79
 None
 1.36A 5vlmC-1jr6A:
undetectable		 5vlmC-1jr6A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_0
(HIV-1 PROTEASE)		 1jr6 HELICASE NS3
(Hepacivirus
C) 		5 / 12 GLY A  36
ASP A  95
GLY A 123
GLY A 128
ILE A 129
 None
 0.77A 6dj1A-1jr6A:
undetectable		 6dj1A-1jr6A:
21.37