SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jr9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 1jr9 MANGANESE SUPEROXIDE
DISMUTASE
(Virgibacillus
halodenitrifican
s) 		3 / 3 PHE A 119
LEU A 161
MET A  89
 None
 0.90A 1mx1D-1jr9A:
undetectable		 1mx1D-1jr9A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 1jr9 MANGANESE SUPEROXIDE
DISMUTASE
(Virgibacillus
halodenitrifican
s) 		5 / 12 GLY A  77
GLY A  76
LEU A  54
SER A  53
LEU A  49
 None
 0.96A 1ya4C-1jr9A:
undetectable		 1ya4C-1jr9A:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_A_NCAA192_0
(NICOTINAMIDASE)		 1jr9 MANGANESE SUPEROXIDE
DISMUTASE
(Virgibacillus
halodenitrifican
s) 		5 / 11 PHE A   3
LEU A  39
HIS A  79
LEU A  57
ILE A  58
 None
 1.48A 3o94A-1jr9A:
undetectable		 3o94A-1jr9A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_C_NCAC192_0
(NICOTINAMIDASE)		 1jr9 MANGANESE SUPEROXIDE
DISMUTASE
(Virgibacillus
halodenitrifican
s) 		5 / 11 PHE A   3
LEU A  39
HIS A  79
LEU A  57
ILE A  58
 None
 1.50A 3o94C-1jr9A:
undetectable		 3o94C-1jr9A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_D_NCAD192_0
(NICOTINAMIDASE)		 1jr9 MANGANESE SUPEROXIDE
DISMUTASE
(Virgibacillus
halodenitrifican
s) 		5 / 11 PHE A   3
LEU A  39
HIS A  79
LEU A  57
ILE A  58
 None
 1.49A 3o94D-1jr9A:
undetectable		 3o94D-1jr9A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_B_SALB503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 1jr9 MANGANESE SUPEROXIDE
DISMUTASE
(Virgibacillus
halodenitrifican
s) 		4 / 7 THR A  23
HIS A  27
PHE A  85
MET A  89
 None
MN  A 204 (-3.2A)
None
None
 1.41A 5u6mB-1jr9A:
undetectable		 5u6mB-1jr9A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E8Q_A_X2NA602_0
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1jr9 MANGANESE SUPEROXIDE
DISMUTASE
(Virgibacillus
halodenitrifican
s) 		5 / 12 GLY A  78
PHE A 115
ILE A 105
PHE A 119
LEU A  88
 None
 1.24A 6e8qA-1jr9A:
undetectable		 6e8qA-1jr9A:
15.76