SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jru'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1jru P47 PROTEIN
(Rattus
norvegicus) 		3 / 3 LEU A 361
HIS A 316
ILE A 318
 None
 0.69A 1s9pB-1jruA:
undetectable		 1s9pB-1jruA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC5_A_NCAA2001_0
(NAD-DEPENDENT
DEACETYLASE)		 1jru P47 PROTEIN
(Rattus
norvegicus) 		4 / 7 SER A 284
ILE A 287
ILE A 321
ASP A 320
 None
 0.93A 1yc5A-1jruA:
undetectable		 1yc5A-1jruA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 1jru P47 PROTEIN
(Rattus
norvegicus) 		3 / 3 LYS A 282
SER A 285
SER A 286
 None
 1.14A 6gbfA-1jruA:
undetectable		 6gbfA-1jruA:
11.14