SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1js8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_B_FLPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 12 VAL A2814
VAL A2795
LEU A2852
GLY A2798
ALA A2797
 None
 1.01A 1eqhB-1js8A:
undetectable		 1eqhB-1js8A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 ASN A2879
PHE A2799
VAL A2867
 None
 0.82A 1kijA-1js8A:
0.0		 1kijA-1js8A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 8 GLY A2535
VAL A2527
SER A2532
ILE A2539
 None
 0.68A 1pk7B-1js8A:
undetectable		 1pk7B-1js8A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R55_A_097A518_1
(ADAM 33)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 10 VAL A2678
HIS A2701
HIS A2702
HIS A2671
ALA A2673
 None
None
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
None
 1.16A 1r55A-1js8A:
undetectable		 1r55A-1js8A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.67A 1rjoA-1js8A:
undetectable		 1rjoA-1js8A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 LEU A2655
HIS A2785
ILE A2789
 None
 0.47A 1s9pB-1js8A:
undetectable		 1s9pB-1js8A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.70A 1w2zA-1js8A:
undetectable		 1w2zA-1js8A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.71A 1w2zB-1js8A:
undetectable		 1w2zB-1js8A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.70A 1w2zC-1js8A:
undetectable		 1w2zC-1js8A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLX_A_CIOA101_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 12 HIS A2671
LEU A2574
THR A2566
MET A2564
GLN A2561
 CUO  A 888 (-3.4A)
None
None
None
None
 1.31A 1xlxA-1js8A:
undetectable		 1xlxA-1js8A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOM_B_CIOB601_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 12 HIS A2671
LEU A2574
THR A2566
MET A2564
GLN A2561
 CUO  A 888 (-3.4A)
None
None
None
None
 1.30A 1xomB-1js8A:
undetectable		 1xomB-1js8A:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_A_NCAA506_0
(NAD-DEPENDENT
DEACETYLASE 2)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 6 ALA A2673
SER A2676
PHE A2646
ASP A2809
 None
 0.95A 1yc2A-1js8A:
undetectable		 1yc2A-1js8A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 6 HIS A2562
ASP A2695
THR A2692
TYR A2691
 CUO  A 888 (-3.4A)
None
CUO  A 888 ( 4.9A)
None
 1.23A 2dysA-1js8A:
undetectable
2dysC-1js8A:
1.0		 2dysA-1js8A:
21.26
2dysC-1js8A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 7 HIS A2562
ASP A2695
THR A2692
TYR A2691
 CUO  A 888 (-3.4A)
None
CUO  A 888 ( 4.9A)
None
 1.22A 2eilA-1js8A:
undetectable
2eilC-1js8A:
1.2		 2eilA-1js8A:
21.26
2eilC-1js8A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 6 HIS A2753
ASN A2747
ILE A2539
GLN A2577
 None
 1.23A 2hkkA-1js8A:
undetectable		 2hkkA-1js8A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.71A 2oqeA-1js8A:
undetectable		 2oqeA-1js8A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.71A 2oqeB-1js8A:
undetectable		 2oqeB-1js8A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.70A 2oqeC-1js8A:
undetectable		 2oqeC-1js8A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.71A 2oqeD-1js8A:
undetectable		 2oqeD-1js8A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.69A 2oqeF-1js8A:
undetectable		 2oqeF-1js8A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.68A 2w0qA-1js8A:
undetectable		 2w0qA-1js8A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.69A 2w0qB-1js8A:
undetectable		 2w0qB-1js8A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRL_A_DXTA1211_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 12 ASN A2534
PRO A2739
THR A2750
GLN A2577
LEU A2574
 None
 1.40A 2xrlA-1js8A:
undetectable		 2xrlA-1js8A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.52A 2zweA-1js8A:
23.0
2zweB-1js8A:
0.0		 2zweA-1js8A:
21.95
2zweB-1js8A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.51A 2zwfA-1js8A:
23.1
2zwfB-1js8A:
0.0		 2zwfA-1js8A:
21.95
2zwfB-1js8A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2571
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 1.46A 2zwfA-1js8A:
23.1
2zwfB-1js8A:
0.0		 2zwfA-1js8A:
21.95
2zwfB-1js8A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.50A 2zwgA-1js8A:
23.1
2zwgB-1js8A:
0.0		 2zwgA-1js8A:
21.95
2zwgB-1js8A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2571
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 1.43A 2zwgA-1js8A:
23.1
2zwgB-1js8A:
0.0		 2zwgA-1js8A:
21.95
2zwgB-1js8A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.73A 3ag2A-1js8A:
0.5		 3ag2A-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_A_DP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 12 TYR A2694
VAL A2622
ILE A2620
SER A2548
SER A2541
 None
 1.44A 3apwA-1js8A:
0.0		 3apwA-1js8A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.73A 3dtuA-1js8A:
0.0		 3dtuA-1js8A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.74A 3dtuC-1js8A:
0.0		 3dtuC-1js8A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.70A 3hiiA-1js8A:
undetectable		 3hiiA-1js8A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_CUB801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2702
HIS A2671
HIS A2571
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.70A 3hiiB-1js8A:
undetectable		 3hiiB-1js8A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 12 GLY A2798
PHE A2796
ASP A2847
ILE A2848
THR A2849
 None
 1.19A 3iv6A-1js8A:
undetectable		 3iv6A-1js8A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB201_1
(PROTEIN S100-A4)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 8 GLY A2825
PHE A2636
PHE A2600
PHE A2647
 None
 0.99A 3ko0B-1js8A:
undetectable
3ko0J-1js8A:
undetectable		 3ko0B-1js8A:
13.47
3ko0J-1js8A:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ201_1
(PROTEIN S100-A4)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 8 PHE A2647
GLY A2825
PHE A2636
PHE A2600
 None
 1.03A 3ko0B-1js8A:
undetectable
3ko0J-1js8A:
undetectable		 3ko0B-1js8A:
13.47
3ko0J-1js8A:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK201_1
(PROTEIN S100-A4)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 8 GLY A2825
PHE A2636
PHE A2600
PHE A2647
 None
 0.99A 3ko0K-1js8A:
undetectable
3ko0S-1js8A:
undetectable		 3ko0K-1js8A:
13.47
3ko0S-1js8A:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS201_1
(PROTEIN S100-A4)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 7 PHE A2647
GLY A2825
PHE A2636
PHE A2600
 None
 1.05A 3ko0K-1js8A:
undetectable
3ko0S-1js8A:
undetectable		 3ko0K-1js8A:
13.47
3ko0S-1js8A:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 ASP A2809
ASN A2811
SER A2676
 None
 0.89A 3lsfB-1js8A:
0.0
3lsfE-1js8A:
undetectable		 3lsfB-1js8A:
21.57
3lsfE-1js8A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NJZ_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 12 HIS A2675
HIS A2671
HIS A2702
HIS A2543
ILE A2669
 CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
None
 1.49A 3njzA-1js8A:
0.0		 3njzA-1js8A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2562
HIS A2571
HIS A2543
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
 0.36A 3qpkA-1js8A:
undetectable		 3qpkA-1js8A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2562
HIS A2571
HIS A2543
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
 0.38A 3qpkB-1js8A:
undetectable		 3qpkB-1js8A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_A_FLRA700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 12 VAL A2814
VAL A2795
LEU A2852
GLY A2798
ALA A2797
 None
 1.01A 3rr3A-1js8A:
0.0		 3rr3A-1js8A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_B_FLRB700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 12 VAL A2814
VAL A2795
LEU A2852
GLY A2798
ALA A2797
 None
 1.01A 3rr3B-1js8A:
0.0		 3rr3B-1js8A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_C_FLRC700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 12 VAL A2814
VAL A2795
LEU A2852
GLY A2798
ALA A2797
 None
 1.01A 3rr3C-1js8A:
0.0		 3rr3C-1js8A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_D_FLRD700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 12 VAL A2814
VAL A2795
LEU A2852
GLY A2798
ALA A2797
 None
 1.01A 3rr3D-1js8A:
undetectable		 3rr3D-1js8A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 PRO A2885
THR A2886
LEU A2800
 None
 0.75A 3ttrA-1js8A:
undetectable		 3ttrA-1js8A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 5 ALA A2618
PRO A2696
TYR A2694
ALA A2540
 None
 1.34A 3twpD-1js8A:
undetectable		 3twpD-1js8A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 8 ASP A2873
ILE A2872
GLY A2871
GLN A2634
 None
 0.73A 4acbB-1js8A:
undetectable
4acbC-1js8A:
undetectable		 4acbB-1js8A:
22.27
4acbC-1js8A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 8 PHE A2615
VAL A2527
TYR A2536
ALA A2581
 None
 0.90A 4m48A-1js8A:
undetectable		 4m48A-1js8A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 8 LEU A2574
TYR A2699
ILE A2591
VAL A2527
 None
 0.87A 4ma7A-1js8A:
undetectable		 4ma7A-1js8A:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 7 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.46A 4p6sA-1js8A:
23.9		 4p6sA-1js8A:
29.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 7 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.55A 4p6sB-1js8A:
23.9		 4p6sB-1js8A:
29.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 LEU A2520
MET A2578
TYR A2593
 None
 0.91A 4p6xG-1js8A:
undetectable		 4p6xG-1js8A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_A_IBPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 10 VAL A2814
VAL A2795
LEU A2852
GLY A2798
ALA A2797
 None
 1.03A 4ph9A-1js8A:
undetectable		 4ph9A-1js8A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_B_IBPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 10 VAL A2814
VAL A2795
LEU A2852
GLY A2798
ALA A2797
 None
 1.02A 4ph9B-1js8A:
undetectable		 4ph9B-1js8A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 6 SER A2710
GLY A2766
ASP A2761
ASP A2768
 None
 0.93A 4uckB-1js8A:
undetectable		 4uckB-1js8A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 TYR A2691
THR A2628
THR A2688
 None
 0.75A 5aoxB-1js8A:
undetectable		 5aoxB-1js8A:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 TYR A2691
THR A2628
THR A2688
 None
 0.78A 5aoxE-1js8A:
0.0		 5aoxE-1js8A:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.72A 5b1bA-1js8A:
undetectable		 5b1bA-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.74A 5b3sN-1js8A:
0.6		 5b3sN-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUQ_A_ACTA1278_0
(NAD(P)H
DEHYDROGENASE
[QUINONE] 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 5 HIS A2543
SER A2693
ILE A2545
TYR A2691
 CUO  A 888 (-3.4A)
None
None
None
 1.45A 5fuqA-1js8A:
0.0
5fuqB-1js8A:
0.0		 5fuqA-1js8A:
19.90
5fuqB-1js8A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWY_E_010E6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 4 THR A2692
LEU A2689
HIS A2562
GLY A2544
 CUO  A 888 ( 4.9A)
None
CUO  A 888 (-3.4A)
None
 1.20A 5gwyA-1js8A:
1.2		 5gwyA-1js8A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 7 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.45A 5i3aA-1js8A:
24.1		 5i3aA-1js8A:
29.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 7 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.45A 5i3aB-1js8A:
24.0		 5i3aB-1js8A:
29.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 7 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.46A 5i3bA-1js8A:
24.0		 5i3bA-1js8A:
29.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 8 SER A2687
THR A2688
ARG A2629
PRO A2631
 None
 1.10A 5jhdE-1js8A:
0.7
5jhdG-1js8A:
undetectable		 5jhdE-1js8A:
20.40
5jhdG-1js8A:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_A_MMSA514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 10 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.41A 5m8nA-1js8A:
0.0		 5m8nA-1js8A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_B_MMSB515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 10 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.48A 5m8nB-1js8A:
22.0		 5m8nB-1js8A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 9 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.47A 5m8nC-1js8A:
3.6		 5m8nC-1js8A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 7 HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.44A 5m8rA-1js8A:
22.1		 5m8rA-1js8A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 8 HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.40A 5m8rB-1js8A:
21.9		 5m8rB-1js8A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 8 HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.34A 5m8rC-1js8A:
22.1		 5m8rC-1js8A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 8 HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.38A 5m8rD-1js8A:
22.1		 5m8rD-1js8A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2562
HIS A2571
HIS A2543
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
 0.31A 5migA-1js8A:
undetectable		 5migA-1js8A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 8 ALA A2808
PHE A2799
LEU A2801
ASN A2811
VAL A2867
 None
 1.43A 5nujA-1js8A:
0.0		 5nujA-1js8A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_B_SALB503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 7 THR A2705
HIS A2702
PHE A2698
MET A2686
 None
CUO  A 888 (-3.3A)
None
None
 1.50A 5u6mB-1js8A:
undetectable		 5u6mB-1js8A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.71A 5w97a-1js8A:
0.7		 5w97a-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.73A 5waua-1js8A:
undetectable		 5waua-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.71A 5x19N-1js8A:
0.8		 5x19N-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.72A 5x1bA-1js8A:
undetectable		 5x1bA-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 7 HIS A2562
ASP A2695
THR A2692
TYR A2691
 CUO  A 888 (-3.4A)
None
CUO  A 888 ( 4.9A)
None
 1.17A 5x1bA-1js8A:
undetectable
5x1bC-1js8A:
1.2
5x1bP-1js8A:
0.9		 5x1bA-1js8A:
21.26
5x1bC-1js8A:
22.49
5x1bP-1js8A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.65A 5x1bN-1js8A:
undetectable		 5x1bN-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.67A 5x1fN-1js8A:
0.6		 5x1fN-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.72A 5xdxA-1js8A:
0.0		 5xdxA-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.72A 5xdxN-1js8A:
undetectable		 5xdxN-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.60A 5z0fA-1js8A:
23.5
5z0fB-1js8A:
0.0		 5z0fA-1js8A:
9.57
5z0fB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2571
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 1.48A 5z0fA-1js8A:
23.5
5z0fB-1js8A:
0.0		 5z0fA-1js8A:
9.57
5z0fB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.57A 5z0gA-1js8A:
23.0
5z0gB-1js8A:
0.0		 5z0gA-1js8A:
9.57
5z0gB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.52A 5z0hA-1js8A:
23.0
5z0hB-1js8A:
0.0		 5z0hA-1js8A:
9.57
5z0hB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2571
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 1.42A 5z0hA-1js8A:
23.0
5z0hB-1js8A:
0.0		 5z0hA-1js8A:
9.57
5z0hB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.54A 5z0iA-1js8A:
23.0
5z0iB-1js8A:
0.0		 5z0iA-1js8A:
9.57
5z0iB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2571
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 1.47A 5z0iA-1js8A:
23.0
5z0iB-1js8A:
0.0		 5z0iA-1js8A:
9.57
5z0iB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.55A 5z0jA-1js8A:
23.1
5z0jB-1js8A:
0.0		 5z0jA-1js8A:
9.57
5z0jB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2571
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 1.49A 5z0jA-1js8A:
23.1
5z0jB-1js8A:
0.0		 5z0jA-1js8A:
9.57
5z0jB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.54A 5z0kA-1js8A:
23.0
5z0kB-1js8A:
0.0		 5z0kA-1js8A:
9.57
5z0kB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2571
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 1.49A 5z0kA-1js8A:
23.0
5z0kB-1js8A:
0.0		 5z0kA-1js8A:
9.57
5z0kB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2562
HIS A2543
HIS A2675
HIS A2671
ASP A2706
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
None
 1.41A 5z0kA-1js8A:
23.0
5z0kB-1js8A:
0.0		 5z0kA-1js8A:
9.57
5z0kB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.53A 5z0lA-1js8A:
23.1
5z0lB-1js8A:
0.0		 5z0lA-1js8A:
9.57
5z0lB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2571
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 1.43A 5z0lA-1js8A:
23.1
5z0lB-1js8A:
0.0		 5z0lA-1js8A:
9.57
5z0lB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2562
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 0.51A 5z0mA-1js8A:
23.0
5z0mB-1js8A:
0.0		 5z0mA-1js8A:
12.50
5z0mB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 11 HIS A2543
HIS A2571
HIS A2671
ASN A2672
HIS A2675
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.4A)
None
CUO  A 888 (-3.3A)
 1.32A 5z0mA-1js8A:
23.0
5z0mB-1js8A:
0.0		 5z0mA-1js8A:
12.50
5z0mB-1js8A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 4 HIS A2543
CYH A2560
HIS A2562
HIS A2571
 CUO  A 888 (-3.4A)
CUO  A 888 ( 3.8A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
 0.24A 5zrdA-1js8A:
27.5		 5zrdA-1js8A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA607_0
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2675
HIS A2702
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.3A)
 0.19A 5zrdA-1js8A:
27.6		 5zrdA-1js8A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 5 HIS A2671
HIS A2675
PHE A2698
HIS A2701
HIS A2702
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
None
CUO  A 888 (-3.3A)
 0.36A 5zrdB-1js8A:
4.5		 5zrdB-1js8A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 5 HIS A2543
CYH A2560
HIS A2562
HIS A2571
PHE A2698
 CUO  A 888 (-3.4A)
CUO  A 888 ( 3.8A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.44A 5zrdB-1js8A:
4.5		 5zrdB-1js8A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 5 HIS A2671
HIS A2675
HIS A2702
PHE A2567
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.3A)
CUO  A 888 (-4.8A)
 0.91A 5zrdB-1js8A:
4.5		 5zrdB-1js8A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 4 HIS A2671
HIS A2675
HIS A2701
HIS A2702
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
CUO  A 888 (-3.3A)
 0.23A 5zrdC-1js8A:
27.2		 5zrdC-1js8A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 5 HIS A2543
CYH A2560
HIS A2562
HIS A2571
PHE A2698
 CUO  A 888 (-3.4A)
CUO  A 888 ( 3.8A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.43A 5zrdC-1js8A:
27.2		 5zrdC-1js8A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 5 HIS A2671
HIS A2675
HIS A2702
PHE A2567
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.3A)
CUO  A 888 (-4.8A)
 0.98A 5zrdC-1js8A:
27.2		 5zrdC-1js8A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 5 HIS A2543
CYH A2560
HIS A2562
HIS A2571
PHE A2698
 CUO  A 888 (-3.4A)
CUO  A 888 ( 3.8A)
CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.45A 5zrdD-1js8A:
6.0		 5zrdD-1js8A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 5 HIS A2671
HIS A2675
HIS A2702
PHE A2567
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
CUO  A 888 (-3.3A)
CUO  A 888 (-4.8A)
 0.92A 5zrdD-1js8A:
6.0		 5zrdD-1js8A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 4 HIS A2671
HIS A2675
HIS A2701
HIS A2702
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
CUO  A 888 (-3.3A)
 0.26A 5zrdD-1js8A:
6.0		 5zrdD-1js8A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		4 / 9 HIS A2571
VAL A2583
SER A2587
ASP A2580
 CUO  A 888 (-3.3A)
None
None
None
 0.98A 6c2mD-1js8A:
undetectable		 6c2mD-1js8A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.72A 6giqa-1js8A:
undetectable		 6giqa-1js8A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.67A 6hu9a-1js8A:
undetectable		 6hu9a-1js8A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.74A 6hu9m-1js8A:
undetectable		 6hu9m-1js8A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.71A 6nmfA-1js8A:
1.1		 6nmfA-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		3 / 3 HIS A2671
HIS A2702
HIS A2701
 CUO  A 888 (-3.4A)
CUO  A 888 (-3.3A)
None
 0.71A 6nmfN-1js8A:
undetectable		 6nmfN-1js8A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_D_BEZD701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 1js8 HEMOCYANIN
(Enteroctopus
dofleini) 		5 / 10 SER A2759
LEU A2733
ALA A2726
TRP A2709
PHE A2760
 None
 1.45A 6qgbD-1js8A:
undetectable		 6qgbD-1js8A:
20.60