SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jug'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1N4F_A_ASRA141_0
(LYSOZYME C)		 1jug LYSOZYME
(Tachyglossus
aculeatus) 		4 / 6 ASP A  66
GLY A  67
THR A  69
SER A  72
 None
 0.43A 1n4fA-1jugA:
23.2		 1n4fA-1jugA:
52.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1N4F_A_ASRA141_0
(LYSOZYME C)		 1jug LYSOZYME
(Tachyglossus
aculeatus) 		4 / 6 ASP A  66
THR A  69
PRO A  70
SER A  72
 None
 0.89A 1n4fA-1jugA:
23.2		 1n4fA-1jugA:
52.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 1jug LYSOZYME
(Tachyglossus
aculeatus) 		5 / 12 LEU A  12
LEU A  92
ILE A  88
ILE A  55
ALA A  32
 None
 0.94A 2bxqA-1jugA:
undetectable		 2bxqA-1jugA:
12.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 1jug LYSOZYME
(Tachyglossus
aculeatus) 		3 / 3 ASN A  46
ASP A  52
ASN A  59
 None
 0.37A 4agaA-1jugA:
23.2		 4agaA-1jugA:
52.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4II8_A_010A210_0
(LYSOZYME C)		 1jug LYSOZYME
(Tachyglossus
aculeatus) 		7 / 7 GLU A  35
ASP A  52
GLN A  57
ASN A  59
TRP A  63
ILE A  98
TRP A 108
 None
 0.28A 4ii8A-1jugA:
23.1		 4ii8A-1jugA:
52.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DL9_A_ACTA214_0
(LYSOZYME C)		 1jug LYSOZYME
(Tachyglossus
aculeatus) 		5 / 5 GLU A  35
ASP A  52
TRP A 108
VAL A 109
ALA A 110
 None
 0.65A 5dl9A-1jugA:
22.9		 5dl9A-1jugA:
52.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 1jug LYSOZYME
(Tachyglossus
aculeatus) 		5 / 9 ILE A  88
THR A  31
LEU A  56
TRP A 108
LEU A 105
 None
 1.39A 5fhzB-1jugA:
undetectable		 5fhzB-1jugA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW9_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 1jug LYSOZYME
(Tachyglossus
aculeatus) 		5 / 8 SER A  36
THR A  40
GLY A  54
ALA A  42
GLU A  35
 None
 1.18A 5vw9A-1jugA:
undetectable		 5vw9A-1jugA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 1jug LYSOZYME
(Tachyglossus
aculeatus) 		5 / 12 GLY A  16
GLY A  19
ASN A  11
ASP A  87
ILE A  88
 None
 1.10A 6mhtA-1jugA:
undetectable		 6mhtA-1jugA:
18.40