SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1juh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ8_B_CAMB502_0
(CYTOCHROME P450-CAM)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		5 / 9 PHE A 136
TYR A  35
THR A  53
GLY A  62
THR A 113
 EDO  A2028 (-4.7A)
EDO  A2028 (-4.6A)
EDO  A2028 (-3.1A)
None
None
 1.38A 1dz8B-1juhA:
0.0		 1dz8B-1juhA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		3 / 3 ALA A 196
VAL A 199
TRP A 200
 None
 1.01A 1gmkA-1juhA:
undetectable
1gmkB-1juhA:
undetectable		 1gmkA-1juhA:
3.27
1gmkB-1juhA:
3.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		3 / 3 GLU A  73
HIS A 112
HIS A  68
 CU  A 401 ( 2.8A)
CU  A 401 (-3.2A)
CU  A 401 (-3.2A)
 0.66A 1oe2A-1juhA:
1.1		 1oe2A-1juhA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 5 HIS A 112
GLU A  73
HIS A  68
HIS A  66
 CU  A 401 (-3.2A)
CU  A 401 ( 2.8A)
CU  A 401 (-3.2A)
CU  A 401 ( 3.3A)
 1.03A 1os2A-1juhA:
undetectable		 1os2A-1juhA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 4 HIS A 112
GLU A  73
HIS A  68
HIS A  66
 CU  A 401 (-3.2A)
CU  A 401 ( 2.8A)
CU  A 401 (-3.2A)
CU  A 401 ( 3.3A)
 1.04A 1os2D-1juhA:
undetectable		 1os2D-1juhA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 4 HIS A 112
GLU A  73
HIS A  68
HIS A  66
 CU  A 401 (-3.2A)
CU  A 401 ( 2.8A)
CU  A 401 (-3.2A)
CU  A 401 ( 3.3A)
 1.06A 1utzA-1juhA:
undetectable		 1utzA-1juhA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 4 HIS A 112
GLU A  73
HIS A  68
HIS A  66
 CU  A 401 (-3.2A)
CU  A 401 ( 2.8A)
CU  A 401 (-3.2A)
CU  A 401 ( 3.3A)
 1.09A 1utzB-1juhA:
undetectable		 1utzB-1juhA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 7 LEU A 251
HIS A  21
THR A 124
TYR A  76
 None
 0.94A 1v55C-1juhA:
undetectable
1v55N-1juhA:
undetectable
1v55P-1juhA:
undetectable		 1v55C-1juhA:
21.41
1v55N-1juhA:
20.45
1v55P-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 7 PHE A  75
THR A  53
VAL A  63
GLY A  62
 EDO  A2028 ( 4.7A)
EDO  A2028 (-3.1A)
None
None
 0.96A 2a1mA-1juhA:
0.0		 2a1mA-1juhA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 7 ALA A  25
TYR A  38
ARG A  36
TYR A  35
 None
None
None
EDO  A2028 (-4.6A)
 1.11A 2ajvH-1juhA:
undetectable
2ajvL-1juhA:
undetectable		 2ajvH-1juhA:
21.57
2ajvL-1juhA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 4 HIS A 112
GLU A  73
HIS A  68
HIS A  66
 CU  A 401 (-3.2A)
CU  A 401 ( 2.8A)
CU  A 401 (-3.2A)
CU  A 401 ( 3.3A)
 1.06A 2hu6A-1juhA:
undetectable		 2hu6A-1juhA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 4 LEU A 295
ILE A 287
ILE A 303
ALA A 275
 None
 0.79A 2i30A-1juhA:
undetectable		 2i30A-1juhA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		5 / 9 ASP A 134
HIS A  66
HIS A 112
HIS A  68
LEU A 172
 None
CU  A 401 ( 3.3A)
CU  A 401 (-3.2A)
CU  A 401 (-3.2A)
None
 1.45A 2jihA-1juhA:
undetectable		 2jihA-1juhA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 4 HIS A 112
GLU A  73
HIS A  68
HIS A  66
 CU  A 401 (-3.2A)
CU  A 401 ( 2.8A)
CU  A 401 (-3.2A)
CU  A 401 ( 3.3A)
 1.06A 2ow9B-1juhA:
undetectable		 2ow9B-1juhA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 4 HIS A 112
GLU A  73
HIS A  68
HIS A  66
 CU  A 401 (-3.2A)
CU  A 401 ( 2.8A)
CU  A 401 (-3.2A)
CU  A 401 ( 3.3A)
 1.03A 2ozrC-1juhA:
undetectable		 2ozrC-1juhA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 4 HIS A 112
GLU A  73
HIS A  68
HIS A  66
 CU  A 401 (-3.2A)
CU  A 401 ( 2.8A)
CU  A 401 (-3.2A)
CU  A 401 ( 3.3A)
 1.02A 2ozrD-1juhA:
undetectable		 2ozrD-1juhA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 LEU A 251
HIS A  21
THR A 124
TYR A  76
 None
 0.90A 2y69C-1juhA:
undetectable
2y69N-1juhA:
undetectable
2y69P-1juhA:
undetectable		 2y69C-1juhA:
21.41
2y69N-1juhA:
20.45
2y69P-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 HIS A  21
THR A 124
TYR A  76
LEU A 251
 None
 0.98A 3ablA-1juhA:
undetectable
3ablC-1juhA:
undetectable
3ablP-1juhA:
undetectable		 3ablA-1juhA:
20.45
3ablC-1juhA:
21.41
3ablP-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 LEU A 251
HIS A  21
THR A 124
TYR A  76
 None
 0.97A 3ablC-1juhA:
undetectable
3ablN-1juhA:
undetectable
3ablP-1juhA:
undetectable		 3ablC-1juhA:
21.41
3ablN-1juhA:
20.45
3ablP-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 HIS A  21
THR A 124
TYR A  76
LEU A 251
 None
 0.91A 3abmA-1juhA:
undetectable
3abmC-1juhA:
undetectable
3abmP-1juhA:
undetectable		 3abmA-1juhA:
20.45
3abmC-1juhA:
21.41
3abmP-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 LEU A 251
HIS A  21
THR A 124
TYR A  76
 None
 0.93A 3asnC-1juhA:
undetectable
3asnN-1juhA:
undetectable
3asnP-1juhA:
undetectable		 3asnC-1juhA:
21.41
3asnN-1juhA:
20.45
3asnP-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 HIS A  21
THR A 124
TYR A  76
LEU A 251
 None
 0.94A 3asoA-1juhA:
undetectable
3asoC-1juhA:
undetectable
3asoP-1juhA:
undetectable		 3asoA-1juhA:
20.45
3asoC-1juhA:
21.41
3asoP-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 LEU A 251
HIS A  21
THR A 124
TYR A  76
 None
 0.93A 3asoC-1juhA:
undetectable
3asoN-1juhA:
undetectable
3asoP-1juhA:
undetectable		 3asoC-1juhA:
21.41
3asoN-1juhA:
20.45
3asoP-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 7 GLU A 314
SER A 313
VAL A 284
ARG A  20
 None
 1.35A 3dqtA-1juhA:
undetectable
3dqtB-1juhA:
undetectable		 3dqtA-1juhA:
21.60
3dqtB-1juhA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		5 / 10 PRO A 304
SER A 269
ILE A 287
PRO A  16
GLY A 288
 None
 1.26A 3ijxB-1juhA:
undetectable
3ijxD-1juhA:
undetectable		 3ijxB-1juhA:
22.04
3ijxD-1juhA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		5 / 10 PRO A 304
SER A 269
ILE A 287
PRO A  16
GLY A 288
 None
 1.25A 3iluB-1juhA:
0.0
3iluE-1juhA:
0.0		 3iluB-1juhA:
22.04
3iluE-1juhA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 5 HIS A 112
GLU A  73
HIS A  68
HIS A  66
 CU  A 401 (-3.2A)
CU  A 401 ( 2.8A)
CU  A 401 (-3.2A)
CU  A 401 ( 3.3A)
 1.07A 3likA-1juhA:
undetectable		 3likA-1juhA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 4 HIS A 112
GLU A  73
HIS A  68
HIS A  66
 CU  A 401 (-3.2A)
CU  A 401 ( 2.8A)
CU  A 401 (-3.2A)
CU  A 401 ( 3.3A)
 1.08A 3lilA-1juhA:
undetectable		 3lilA-1juhA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 5 HIS A 112
GLU A  73
HIS A  68
HIS A  66
 CU  A 401 (-3.2A)
CU  A 401 ( 2.8A)
CU  A 401 (-3.2A)
CU  A 401 ( 3.3A)
 1.04A 3lkaA-1juhA:
undetectable		 3lkaA-1juhA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 7 SER A 313
VAL A 284
ARG A  20
GLU A 314
 None
 1.31A 3n5tA-1juhA:
undetectable
3n5tB-1juhA:
0.0		 3n5tA-1juhA:
21.80
3n5tB-1juhA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		5 / 12 GLY A  45
ILE A 287
GLY A 305
ALA A 273
ALA A 275
 None
 0.80A 3sudB-1juhA:
undetectable		 3sudB-1juhA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		5 / 12 GLY A  45
ILE A 287
GLY A 305
ALA A 273
ALA A 275
 None
 0.92A 3sudC-1juhA:
undetectable		 3sudC-1juhA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		5 / 12 GLY A 329
ILE A 287
PHE A 276
ALA A 275
ALA A 301
 None
 1.04A 3sueA-1juhA:
undetectable		 3sueA-1juhA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		5 / 12 GLY A 329
ILE A 287
PHE A 276
ALA A 275
ALA A 301
 None
 1.01A 3sufB-1juhA:
undetectable		 3sufB-1juhA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 HIS A  21
THR A 124
TYR A  76
LEU A 251
 None
 0.88A 3wg7A-1juhA:
undetectable
3wg7C-1juhA:
undetectable
3wg7P-1juhA:
undetectable		 3wg7A-1juhA:
20.45
3wg7C-1juhA:
21.41
3wg7P-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 LEU A 251
HIS A  21
THR A 124
TYR A  76
 None
 0.87A 3wg7C-1juhA:
undetectable
3wg7N-1juhA:
undetectable
3wg7P-1juhA:
undetectable		 3wg7C-1juhA:
21.41
3wg7N-1juhA:
20.45
3wg7P-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 HIS A  21
THR A 124
TYR A  76
LEU A 251
 None
 0.86A 3x2qA-1juhA:
undetectable
3x2qC-1juhA:
undetectable
3x2qP-1juhA:
undetectable		 3x2qA-1juhA:
20.45
3x2qC-1juhA:
21.41
3x2qP-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 LEU A 251
HIS A  21
THR A 124
TYR A  76
 None
 0.93A 3x2qC-1juhA:
undetectable
3x2qN-1juhA:
undetectable
3x2qP-1juhA:
undetectable		 3x2qC-1juhA:
21.41
3x2qN-1juhA:
20.45
3x2qP-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 5 VAL A  97
LEU A  98
SER A  99
MET A 123
 None
None
None
EDO  A2028 (-4.7A)
 1.25A 4e1gA-1juhA:
0.0		 4e1gA-1juhA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 7 GLU A 314
SER A 313
VAL A 284
ARG A  20
 None
 1.39A 4k5jA-1juhA:
undetectable
4k5jB-1juhA:
0.0		 4k5jA-1juhA:
21.85
4k5jB-1juhA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 7 GLU A 314
SER A 313
VAL A 284
ARG A  20
 None
 1.33A 5adlA-1juhA:
undetectable
5adlB-1juhA:
0.0		 5adlA-1juhA:
21.85
5adlB-1juhA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 HIS A  21
THR A 124
TYR A  76
LEU A 251
 None
 0.88A 5b1aA-1juhA:
undetectable
5b1aC-1juhA:
undetectable
5b1aP-1juhA:
undetectable		 5b1aA-1juhA:
20.45
5b1aC-1juhA:
21.41
5b1aP-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 HIS A  21
THR A 124
TYR A  76
LEU A 251
 None
 1.05A 5b1bA-1juhA:
undetectable
5b1bC-1juhA:
undetectable
5b1bP-1juhA:
undetectable		 5b1bA-1juhA:
20.45
5b1bC-1juhA:
21.41
5b1bP-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 HIS A  21
THR A 124
TYR A  76
LEU A 251
 None
 0.87A 5b3sA-1juhA:
undetectable
5b3sC-1juhA:
undetectable
5b3sP-1juhA:
undetectable		 5b3sA-1juhA:
20.45
5b3sC-1juhA:
21.41
5b3sP-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 7 GLU A 314
SER A 313
VAL A 284
ARG A  20
 None
 1.34A 5fj3A-1juhA:
undetectable
5fj3B-1juhA:
undetectable		 5fj3A-1juhA:
21.85
5fj3B-1juhA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		3 / 3 ASN A 248
SER A 325
SER A 324
 NAG  A 504 (-1.9A)
NAG  A 504 (-3.1A)
None
 0.74A 5gsnA-1juhA:
undetectable		 5gsnA-1juhA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 LEU A 251
HIS A  21
THR A 124
TYR A  76
 None
 0.92A 5iy5C-1juhA:
undetectable
5iy5N-1juhA:
undetectable
5iy5P-1juhA:
undetectable		 5iy5C-1juhA:
21.13
5iy5N-1juhA:
20.45
5iy5P-1juhA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_ACTA405_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		3 / 3 GLN A 332
THR A 250
ASP A 331
 None
 0.94A 5k9dA-1juhA:
undetectable		 5k9dA-1juhA:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 4 HIS A 112
GLU A  73
HIS A  68
HIS A  66
 CU  A 401 (-3.2A)
CU  A 401 ( 2.8A)
CU  A 401 (-3.2A)
CU  A 401 ( 3.3A)
 1.08A 5n5jA-1juhA:
undetectable		 5n5jA-1juhA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 7 GLU A 314
SER A 313
VAL A 284
ARG A  20
 None
 1.33A 5vv7A-1juhA:
undetectable
5vv7B-1juhA:
undetectable		 5vv7A-1juhA:
21.85
5vv7B-1juhA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 7 GLU A 314
SER A 313
VAL A 284
ARG A  20
 None
 1.34A 5vvnA-1juhA:
undetectable
5vvnB-1juhA:
0.0		 5vvnA-1juhA:
21.85
5vvnB-1juhA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 HIS A  21
THR A 124
TYR A  76
LEU A 251
 None
 0.90A 5w97A-1juhA:
undetectable
5w97C-1juhA:
undetectable
5w97c-1juhA:
undetectable		 5w97A-1juhA:
20.45
5w97C-1juhA:
21.41
5w97c-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 7 LEU A 251
HIS A  21
THR A 124
TYR A  76
 None
 0.87A 5w97C-1juhA:
undetectable
5w97a-1juhA:
undetectable
5w97c-1juhA:
undetectable		 5w97C-1juhA:
21.41
5w97a-1juhA:
20.45
5w97c-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 HIS A  21
THR A 124
TYR A  76
LEU A 251
 None
 0.89A 5wauA-1juhA:
undetectable
5wauC-1juhA:
undetectable
5wauc-1juhA:
undetectable		 5wauA-1juhA:
20.45
5wauC-1juhA:
21.41
5wauc-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 7 LEU A 251
HIS A  21
THR A 124
TYR A  76
 None
 0.89A 5wauC-1juhA:
undetectable
5waua-1juhA:
undetectable
5wauc-1juhA:
undetectable		 5wauC-1juhA:
21.41
5waua-1juhA:
20.45
5wauc-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 HIS A  21
THR A 124
TYR A  76
LEU A 251
 None
 0.93A 5x19A-1juhA:
undetectable
5x19C-1juhA:
undetectable
5x19P-1juhA:
undetectable		 5x19A-1juhA:
20.45
5x19C-1juhA:
21.41
5x19P-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		3 / 3 ARG A  15
PHE A 309
LEU A   5
 None
 0.93A 5x1bC-1juhA:
undetectable		 5x1bC-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 7 HIS A  21
THR A 124
TYR A  76
LEU A 251
 None
 1.04A 5x1bA-1juhA:
undetectable
5x1bC-1juhA:
undetectable
5x1bP-1juhA:
undetectable		 5x1bA-1juhA:
20.45
5x1bC-1juhA:
21.41
5x1bP-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 7 HIS A  21
THR A 124
TYR A  76
LEU A 251
 None
 0.91A 5x1fA-1juhA:
undetectable
5x1fC-1juhA:
undetectable
5x1fP-1juhA:
undetectable		 5x1fA-1juhA:
20.45
5x1fC-1juhA:
21.41
5x1fP-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 HIS A  21
THR A 124
TYR A  76
LEU A 251
 None
 0.89A 5xdqA-1juhA:
undetectable
5xdqC-1juhA:
undetectable
5xdqP-1juhA:
undetectable		 5xdqA-1juhA:
20.45
5xdqC-1juhA:
21.41
5xdqP-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 LEU A 251
HIS A  21
THR A 124
TYR A  76
 None
 0.94A 5xdqC-1juhA:
undetectable
5xdqN-1juhA:
undetectable
5xdqP-1juhA:
undetectable		 5xdqC-1juhA:
21.41
5xdqN-1juhA:
20.45
5xdqP-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 LEU A 251
HIS A  21
THR A 124
TYR A  76
 None
 0.94A 5xdxC-1juhA:
undetectable
5xdxN-1juhA:
0.0
5xdxP-1juhA:
undetectable		 5xdxC-1juhA:
21.47
5xdxN-1juhA:
20.45
5xdxP-1juhA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 HIS A  21
THR A 124
TYR A  76
LEU A 251
 None
 0.88A 5z84A-1juhA:
undetectable
5z84C-1juhA:
undetectable
5z84P-1juhA:
undetectable		 5z84A-1juhA:
20.45
5z84C-1juhA:
21.41
5z84P-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 7 LEU A 251
HIS A  21
THR A 124
TYR A  76
 None
 0.94A 5z84C-1juhA:
undetectable
5z84N-1juhA:
undetectable
5z84P-1juhA:
undetectable		 5z84C-1juhA:
21.41
5z84N-1juhA:
20.45
5z84P-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 HIS A  21
THR A 124
TYR A  76
LEU A 251
 None
 0.85A 5z85A-1juhA:
undetectable
5z85C-1juhA:
undetectable
5z85P-1juhA:
undetectable		 5z85A-1juhA:
20.45
5z85C-1juhA:
21.41
5z85P-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 7 LEU A 251
HIS A  21
THR A 124
TYR A  76
 None
 0.90A 5z85C-1juhA:
undetectable
5z85N-1juhA:
undetectable
5z85P-1juhA:
undetectable		 5z85C-1juhA:
21.41
5z85N-1juhA:
20.45
5z85P-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 HIS A  21
THR A 124
TYR A  76
LEU A 251
 None
 0.86A 5z86A-1juhA:
undetectable
5z86C-1juhA:
undetectable
5z86P-1juhA:
undetectable		 5z86A-1juhA:
20.45
5z86C-1juhA:
21.41
5z86P-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 LEU A 251
HIS A  21
THR A 124
TYR A  76
 None
 0.91A 5z86C-1juhA:
undetectable
5z86N-1juhA:
undetectable
5z86P-1juhA:
undetectable		 5z86C-1juhA:
21.41
5z86N-1juhA:
20.45
5z86P-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 HIS A  21
THR A 124
TYR A  76
LEU A 251
 None
 0.87A 5zcoA-1juhA:
undetectable
5zcoC-1juhA:
undetectable
5zcoP-1juhA:
undetectable		 5zcoA-1juhA:
20.45
5zcoC-1juhA:
21.41
5zcoP-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 LEU A 251
HIS A  21
THR A 124
TYR A  76
 None
 0.90A 5zcoC-1juhA:
undetectable
5zcoN-1juhA:
undetectable
5zcoP-1juhA:
undetectable		 5zcoC-1juhA:
21.41
5zcoN-1juhA:
20.45
5zcoP-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 HIS A  21
THR A 124
TYR A  76
LEU A 251
 None
 0.88A 5zcpA-1juhA:
undetectable
5zcpC-1juhA:
undetectable
5zcpP-1juhA:
undetectable		 5zcpA-1juhA:
20.45
5zcpC-1juhA:
21.41
5zcpP-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 LEU A 251
HIS A  21
THR A 124
TYR A  76
 None
 0.91A 5zcpC-1juhA:
undetectable
5zcpN-1juhA:
undetectable
5zcpP-1juhA:
undetectable		 5zcpC-1juhA:
21.41
5zcpN-1juhA:
20.45
5zcpP-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 HIS A  21
THR A 124
TYR A  76
LEU A 251
 None
 0.86A 5zcqA-1juhA:
undetectable
5zcqC-1juhA:
undetectable
5zcqP-1juhA:
undetectable		 5zcqA-1juhA:
20.45
5zcqC-1juhA:
21.41
5zcqP-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA607_0
(TYROSINASE)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		3 / 3 HIS A  66
HIS A 112
HIS A  68
 CU  A 401 ( 3.3A)
CU  A 401 (-3.2A)
CU  A 401 (-3.2A)
 0.43A 5zrdA-1juhA:
undetectable		 5zrdA-1juhA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 7 SER A 313
VAL A 284
ARG A  20
GLU A 314
 None
 1.36A 6av6A-1juhA:
undetectable
6av6B-1juhA:
0.0		 6av6A-1juhA:
13.90
6av6B-1juhA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 7 SER A 313
VAL A 284
ARG A  20
GLU A 314
 None
 1.42A 6av7A-1juhA:
undetectable
6av7B-1juhA:
0.0		 6av7A-1juhA:
13.90
6av7B-1juhA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 PHE A  48
VAL A  14
SER A  43
TYR A  17
 None
 1.08A 6huoC-1juhA:
undetectable
6huoD-1juhA:
0.0		 6huoC-1juhA:
11.14
6huoD-1juhA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 8 LEU A 251
HIS A  21
THR A 124
TYR A  76
 None
 0.98A 6nknC-1juhA:
undetectable
6nknN-1juhA:
undetectable
6nknP-1juhA:
undetectable		 6nknC-1juhA:
21.41
6nknN-1juhA:
20.45
6nknP-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1juh QUERCETIN
2,3-DIOXYGENASE
(Aspergillus
japonicus) 		4 / 7 HIS A  21
THR A 124
TYR A  76
LEU A 251
 None
 1.03A 6nmfA-1juhA:
undetectable
6nmfC-1juhA:
undetectable
6nmfP-1juhA:
undetectable		 6nmfA-1juhA:
20.45
6nmfC-1juhA:
21.41
6nmfP-1juhA:
21.41