SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jv1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		5 / 10 MET A 171
ALA A 109
LEU A 107
LEU A 106
ILE A 192
 None
 1.30A 1a52A-1jv1A:
undetectable		 1a52A-1jv1A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		5 / 10 MET A 171
ALA A 109
LEU A 107
LEU A 106
ILE A 192
 None
 1.33A 1a52B-1jv1A:
0.0		 1a52B-1jv1A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		5 / 9 MET A 171
ALA A 109
LEU A 107
LEU A 106
ILE A 192
 None
 1.30A 1ereA-1jv1A:
undetectable		 1ereA-1jv1A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		5 / 9 MET A 171
ALA A 109
LEU A 107
LEU A 106
ILE A 192
 None
 1.31A 1ereB-1jv1A:
0.0		 1ereB-1jv1A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		5 / 9 MET A 171
ALA A 109
LEU A 107
LEU A 106
ILE A 192
 None
 1.31A 1ereC-1jv1A:
undetectable		 1ereC-1jv1A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		5 / 9 MET A 171
ALA A 109
LEU A 107
LEU A 106
ILE A 192
 None
 1.30A 1ereD-1jv1A:
0.0		 1ereD-1jv1A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		4 / 8 SER A 471
ILE A 470
LEU A 477
GLU A 475
 None
 0.81A 1eupA-1jv1A:
0.0		 1eupA-1jv1A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLF_A_NVPA999_1
(HIV-1 RT A-CHAIN
HIV-1 RT B-CHAIN)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		4 / 8 LEU A 425
VAL A 127
GLY A 128
GLU A 465
 None
 0.91A 1jlfA-1jv1A:
undetectable
1jlfB-1jv1A:
0.0		 1jlfA-1jv1A:
21.11
1jlfB-1jv1A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOS_A_VIAA1_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		5 / 12 LEU A 106
SER A 173
MET A 171
GLN A 233
PHE A 194
 None
 1.48A 1xosA-1jv1A:
undetectable		 1xosA-1jv1A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOT_B_VDNB102_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		5 / 12 LEU A 106
SER A 173
MET A 171
GLN A 233
PHE A 194
 None
 1.44A 1xotB-1jv1A:
undetectable		 1xotB-1jv1A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2003_1
(SERUM ALBUMIN)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		5 / 10 ARG A 422
LEU A 129
ILE A 138
PHE A 136
GLY A 123
 None
 1.25A 2bxqA-1jv1A:
0.0		 2bxqA-1jv1A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		4 / 6 ALA A 260
TYR A 472
ILE A 143
ILE A  98
 None
 1.15A 2dcfA-1jv1A:
0.0		 2dcfA-1jv1A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_2
(THYROXINE-BINDING
GLOBULIN)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		3 / 3 LEU A 146
ARG A 142
ILE A 160
 None
 0.57A 2xn5B-1jv1A:
0.0		 2xn5B-1jv1A:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZB7_A_NCAA901_0
(PROSTAGLANDIN
REDUCTASE 2)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		4 / 5 TYR A 163
ILE A 247
LEU A 226
LEU A 230
 None
 0.94A 2zb7A-1jv1A:
2.0		 2zb7A-1jv1A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		4 / 7 ALA A 260
TYR A 472
ILE A 143
ILE A  98
 None
 1.15A 2zm7A-1jv1A:
0.0		 2zm7A-1jv1A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX94_0
(PROTEIN S100-B)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		3 / 3 PHE A 386
CYH A 275
PHE A 333
 None
 1.02A 3cr5X-1jv1A:
undetectable		 3cr5X-1jv1A:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX94_0
(PROTEIN S100-B)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		3 / 3 PHE A 386
CYH A 275
PHE A 337
 None
 1.09A 3cr5X-1jv1A:
undetectable		 3cr5X-1jv1A:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		3 / 4 SER A 305
GLY A 222
GLU A 346
 None
UD1  A 901 (-3.1A)
None
 0.69A 3raeA-1jv1A:
undetectable
3raeC-1jv1A:
undetectable		 3raeA-1jv1A:
21.76
3raeC-1jv1A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		5 / 12 ILE A 164
PHE A 194
ILE A 247
LEU A 338
VAL A 342
 None
 1.11A 3w68B-1jv1A:
1.9		 3w68B-1jv1A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		4 / 6 ASN A 417
ARG A 422
TYR A 125
LEU A 116
 None
 1.49A 4f8yA-1jv1A:
undetectable
4f8yB-1jv1A:
undetectable		 4f8yA-1jv1A:
16.04
4f8yB-1jv1A:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		4 / 7 ARG A 422
TYR A 125
LEU A 116
ASN A 417
 None
 1.33A 4f8yC-1jv1A:
0.0
4f8yD-1jv1A:
0.0		 4f8yC-1jv1A:
16.04
4f8yD-1jv1A:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		5 / 12 VAL A 301
ALA A 277
PHE A 392
VAL A 341
VAL A 298
 None
 0.95A 4ib4A-1jv1A:
undetectable		 4ib4A-1jv1A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		4 / 8 ILE A 269
GLU A  93
GLN A  97
ILE A  98
 None
 0.70A 4mj8A-1jv1A:
undetectable		 4mj8A-1jv1A:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		3 / 3 ALA A 231
GLN A 195
GLY A 168
 None
 0.62A 4odoC-1jv1A:
undetectable		 4odoC-1jv1A:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_D_ACTD201_0
(RETINOL-BINDING
PROTEIN 2)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		3 / 3 ASP A 384
HIS A 352
LYS A 380
 None
 0.77A 4qzuD-1jv1A:
0.0		 4qzuD-1jv1A:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		4 / 6 PHE A 332
SER A 246
VAL A 103
ASP A 261
 None
 1.27A 5hesA-1jv1A:
undetectable		 5hesA-1jv1A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		6 / 12 GLY A 111
GLY A 224
GLY A 222
HIS A 352
GLU A 379
PHE A 386
 UD1  A 901 (-3.5A)
None
UD1  A 901 (-3.1A)
None
None
None
 1.31A 5vimB-1jv1A:
undetectable		 5vimB-1jv1A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		3 / 3 ASN A 254
VAL A 382
HIS A 331
 None
 0.84A 6a5yD-1jv1A:
undetectable		 6a5yD-1jv1A:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		4 / 5 ASN A 495
VAL A 481
LEU A 477
SER A 467
 None
 1.31A 6a7pA-1jv1A:
undetectable		 6a7pA-1jv1A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 1jv1 GLCNAC1P
URIDYLTRANSFERASE
ISOFORM 1: AGX1
(Homo
sapiens) 		3 / 3 VAL A 280
GLU A 396
ILE A 328
 None
 0.44A 6f7lB-1jv1A:
undetectable		 6f7lB-1jv1A:
21.63