SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jw0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FBY_B_9CRB1500_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	1jw0	CEPHALOSPORIN ACYLASE ALPHA CHAIN (Brevundimonas diminuta)	6 / 12	ILE A 111 ALA A 115 ALA A 113 GLN A 116 LEU A 130 VAL A 137	None	1.37A	1fbyB-1jw0A: undetectable	1fbyB-1jw0A: 22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FKF_A_FK5A108_1 (FK506 BINDING PROTEIN)	1jw0	CEPHALOSPORIN ACYLASE ALPHA CHAIN (Brevundimonas diminuta)	5 / 11	TYR A 42 ILE A 111 TYR A 58 HIS A 140 PHE A 107	None	1.35A	1fkfA-1jw0A: undetectable	1fkfA-1jw0A: 19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FKJ_A_FK5A108_1 (FK506 BINDING PROTEIN)	1jw0	CEPHALOSPORIN ACYLASE ALPHA CHAIN (Brevundimonas diminuta)	5 / 11	TYR A 42 ILE A 111 TYR A 58 HIS A 140 PHE A 107	None	1.34A	1fkjA-1jw0A: undetectable	1fkjA-1jw0A: 19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QJ7_A_SPMA264_1 (THYMIDYLATE SYNTHASE)	1jw0	CEPHALOSPORIN ACYLASE ALPHA CHAIN (Brevundimonas diminuta)	4 / 8	ALA A 89 GLN A 90 ASP A 136 SER A 133	None	0.89A	3qj7A-1jw0A: undetectable 3qj7D-1jw0A: undetectable	3qj7A-1jw0A: 20.66 3qj7D-1jw0A: 20.66

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FBY_B_9CRB1500_1","RETINOIC ACID RECEPTOR RXR-ALPHA","1jw0","CEPHALOSPORIN ACYLASE ALPHA CHAIN","Brevundimonas diminuta",6,"ILE A 111;ALA A 115;ALA A 113;GLN A 116;LEU A 130;VAL A 137","None","1.37A","1fbyB-1jw0A:undetectable","1fbyB-1jw0A:22.17"],["1FKF_A_FK5A108_1","FK506 BINDING PROTEIN","1jw0","CEPHALOSPORIN ACYLASE ALPHA CHAIN","Brevundimonas diminuta",5,"TYR A  42;ILE A 111;TYR A  58;HIS A 140;PHE A 107","None","1.35A","1fkfA-1jw0A:undetectable","1fkfA-1jw0A:19.50"],["1FKJ_A_FK5A108_1","FK506 BINDING PROTEIN","1jw0","CEPHALOSPORIN ACYLASE ALPHA CHAIN","Brevundimonas diminuta",5,"TYR A  42;ILE A 111;TYR A  58;HIS A 140;PHE A 107","None","1.34A","1fkjA-1jw0A:undetectable","1fkjA-1jw0A:19.50"],["3QJ7_A_SPMA264_1","THYMIDYLATE SYNTHASE;THYMIDYLATE SYNTHASE","1jw0","CEPHALOSPORIN ACYLASE ALPHA CHAIN","Brevundimonas diminuta",4,"ALA A  89;GLN A  90;ASP A 136;SER A 133","None","0.89A","3qj7A-1jw0A:undetectable;3qj7D-1jw0A:undetectable","3qj7A-1jw0A:20.66;3qj7D-1jw0A:20.66"]]