SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jwe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 1jwe PROTEIN (DNAB
HELICASE)
(Escherichia
coli) 		3 / 3 LEU A  42
SER A  35
ASN A 117
 None
 0.77A 1bx4A-1jweA:
undetectable		 1bx4A-1jweA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)		 1jwe PROTEIN (DNAB
HELICASE)
(Escherichia
coli) 		4 / 4 LEU A  83
LEU A  90
SER A  89
LEU A  74
 None
 1.18A 1ya3A-1jweA:
0.0		 1ya3A-1jweA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_2
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 1jwe PROTEIN (DNAB
HELICASE)
(Escherichia
coli) 		3 / 3 VAL A 125
VAL A  55
ASP A  43
 None
 0.73A 2fumD-1jweA:
undetectable		 2fumD-1jweA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 1jwe PROTEIN (DNAB
HELICASE)
(Escherichia
coli) 		5 / 12 LEU A  83
LEU A  86
GLN A  93
ARG A  73
LEU A  37
 None
 1.39A 3d90A-1jweA:
undetectable		 3d90A-1jweA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_2
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 1jwe PROTEIN (DNAB
HELICASE)
(Escherichia
coli) 		3 / 3 ARG A  53
THR A  61
THR A 112
 None
 0.73A 3k2hB-1jweA:
undetectable		 3k2hB-1jweA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1jwe PROTEIN (DNAB
HELICASE)
(Escherichia
coli) 		3 / 3 VAL A  55
ALA A  51
PHE A  68
 None
 0.92A 4w5nA-1jweA:
undetectable		 4w5nA-1jweA:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_A_MMZA601_1
(LACTOPEROXIDASE)		 1jwe PROTEIN (DNAB
HELICASE)
(Escherichia
coli) 		4 / 5 GLN A  34
HIS A  64
GLU A 107
LEU A 108
 None
 1.37A 5ff1A-1jweA:
undetectable		 5ff1A-1jweA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_A_MMZA602_1
(LACTOPEROXIDASE)		 1jwe PROTEIN (DNAB
HELICASE)
(Escherichia
coli) 		4 / 5 GLN A  34
HIS A  64
GLU A 107
LEU A 108
 None
 1.37A 5ff1A-1jweA:
undetectable		 5ff1A-1jweA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_B_MMZB601_1
(LACTOPEROXIDASE)		 1jwe PROTEIN (DNAB
HELICASE)
(Escherichia
coli) 		4 / 5 GLN A  34
HIS A  64
GLU A 107
LEU A 108
 None
 1.37A 5ff1B-1jweA:
undetectable		 5ff1B-1jweA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_B_MMZB613_1
(LACTOPEROXIDASE)		 1jwe PROTEIN (DNAB
HELICASE)
(Escherichia
coli) 		4 / 5 GLN A  34
HIS A  64
GLU A 107
LEU A 108
 None
 1.37A 5ff1B-1jweA:
undetectable		 5ff1B-1jweA:
11.73