SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jwi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 1jwi PLATELET AGGREGATION
INDUCER
(Bitis
arietans) 		3 / 3 VAL B 120
TRP B  25
TRP B  67
 None
 1.13A 2xdcA-1jwiB:
undetectable
2xdcB-1jwiB:
undetectable		 2xdcA-1jwiB:
13.41
2xdcB-1jwiB:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 1jwi PLATELET AGGREGATION
INDUCER
(Bitis
arietans) 		3 / 3 VAL B 120
TRP B  67
TRP B  25
 None
 1.45A 2xdcA-1jwiB:
undetectable
2xdcB-1jwiB:
undetectable		 2xdcA-1jwiB:
13.41
2xdcB-1jwiB:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 1jwi PLATELET AGGREGATION
INDUCER
(Bitis
arietans) 		3 / 3 TRP B  25
VAL B 120
TRP B  67
 None
 1.45A 2xdcA-1jwiB:
undetectable
2xdcB-1jwiB:
undetectable		 2xdcA-1jwiB:
13.41
2xdcB-1jwiB:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 1jwi PLATELET AGGREGATION
INDUCER
(Bitis
arietans) 		3 / 3 TRP B  67
VAL B 120
TRP B  25
 None
 1.15A 2xdcA-1jwiB:
undetectable
2xdcB-1jwiB:
undetectable		 2xdcA-1jwiB:
13.41
2xdcB-1jwiB:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 1jwi PLATELET AGGREGATION
INDUCER
(Bitis
arietans) 		3 / 3 VAL B 120
TRP B  25
TRP B  67
 None
 1.14A 2xdcC-1jwiB:
undetectable
2xdcD-1jwiB:
undetectable		 2xdcC-1jwiB:
13.41
2xdcD-1jwiB:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 1jwi PLATELET AGGREGATION
INDUCER
(Bitis
arietans) 		3 / 3 TRP B  67
VAL B 120
TRP B  25
 None
 1.02A 2xdcC-1jwiB:
undetectable
2xdcD-1jwiB:
undetectable		 2xdcC-1jwiB:
13.41
2xdcD-1jwiB:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 1jwi PLATELET AGGREGATION
INDUCER
(Bitis
arietans) 		3 / 3 TRP B  67
VAL B 120
TRP B  25
 None
 1.04A 2xdcE-1jwiB:
undetectable
2xdcF-1jwiB:
undetectable		 2xdcE-1jwiB:
13.41
2xdcF-1jwiB:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1jwi PLATELET AGGREGATION
INDUCER
(Bitis
arietans) 		3 / 3 VAL B 120
TRP B  25
TRP B  67
 None
 1.12A 2y5mA-1jwiB:
undetectable
2y5mB-1jwiB:
undetectable		 2y5mA-1jwiB:
13.41
2y5mB-1jwiB:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1jwi PLATELET AGGREGATION
INDUCER
(Bitis
arietans) 		3 / 3 VAL B 120
TRP B  67
TRP B  25
 None
 1.44A 2y5mA-1jwiB:
undetectable
2y5mB-1jwiB:
undetectable		 2y5mA-1jwiB:
13.41
2y5mB-1jwiB:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 1jwi PLATELET AGGREGATION
INDUCER
(Bitis
arietans) 		3 / 3 TRP B  67
VAL B 120
TRP B  25
 None
 1.02A 2y5mE-1jwiB:
undetectable
2y5mF-1jwiB:
undetectable		 2y5mE-1jwiB:
13.41
2y5mF-1jwiB:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1jwi PLATELET AGGREGATION
INDUCER
(Bitis
arietans) 		3 / 3 VAL B 120
TRP B  25
TRP B  67
 None
 1.12A 2y6nA-1jwiB:
undetectable
2y6nB-1jwiB:
undetectable		 2y6nA-1jwiB:
13.41
2y6nB-1jwiB:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1jwi PLATELET AGGREGATION
INDUCER
(Bitis
arietans) 		3 / 3 VAL B 120
TRP B  67
TRP B  25
 None
 1.45A 2y6nA-1jwiB:
undetectable
2y6nB-1jwiB:
undetectable		 2y6nA-1jwiB:
13.41
2y6nB-1jwiB:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 1jwi PLATELET AGGREGATION
INDUCER
(Bitis
arietans) 		3 / 3 TRP B  25
VAL B 120
TRP B  67
 None
 1.44A 2y6nA-1jwiB:
undetectable
2y6nB-1jwiB:
undetectable		 2y6nA-1jwiB:
13.41
2y6nB-1jwiB:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 1jwi PLATELET AGGREGATION
INDUCER
(Bitis
arietans) 		3 / 3 TRP B  67
VAL B 120
TRP B  25
 None
 1.13A 2y6nA-1jwiB:
undetectable
2y6nB-1jwiB:
undetectable		 2y6nA-1jwiB:
13.41
2y6nB-1jwiB:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1jwi PLATELET AGGREGATION
INDUCER
(Bitis
arietans) 		3 / 3 TRP B  67
VAL B 120
TRP B  25
 None
 1.00A 2y6nC-1jwiB:
undetectable
2y6nD-1jwiB:
undetectable		 2y6nC-1jwiB:
13.41
2y6nD-1jwiB:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 1jwi PLATELET AGGREGATION
INDUCER
(Bitis
arietans) 		3 / 3 TRP B  67
VAL B 120
TRP B  25
 None
 1.00A 2y6nE-1jwiB:
undetectable
2y6nF-1jwiB:
undetectable		 2y6nE-1jwiB:
13.41
2y6nF-1jwiB:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_B_SAMB402_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 1jwi BITISCETIN
(Bitis
arietans) 		5 / 12 PHE A 101
LEU A 115
PHE A 123
GLY A  69
PHE A  19
 None
 1.42A 2zznB-1jwiA:
undetectable		 2zznB-1jwiA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1jwi PLATELET AGGREGATION
INDUCER
(Bitis
arietans) 		3 / 3 VAL B 120
TRP B  25
TRP B  67
 None
 1.08A 3zq8A-1jwiB:
undetectable
3zq8B-1jwiB:
undetectable		 3zq8A-1jwiB:
13.41
3zq8B-1jwiB:
13.41