SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jx2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		4 / 7 GLU A 303
PHE A 356
THR A 338
ALA A 299
 None
 1.09A 1fo4B-1jx2A:
0.0		 1fo4B-1jx2A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_2
(LIVER
CARBOXYLESTERASE I)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		3 / 3 PHE A 393
LEU A 365
LEU A 432
 None
 0.63A 1mx1E-1jx2A:
undetectable		 1mx1E-1jx2A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N6C_A_SAMA402_0
(SET
DOMAIN-CONTAINING
PROTEIN 7)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 11 ILE A 668
ALA A 194
GLY A 195
GLU A 198
ASN A 238
 None
ADP  A1203 (-4.3A)
ADP  A1203 (-3.1A)
ADP  A1203 (-4.1A)
None
 1.10A 1n6cA-1jx2A:
undetectable		 1n6cA-1jx2A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		3 / 3 LYS A 822
ASP A 805
ASP A 922
 None
 0.97A 2br4D-1jx2A:
undetectable		 2br4D-1jx2A:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 LEU A 318
LEU A 296
ILE A 291
ILE A 359
ALA A 360
 None
 1.08A 2bxcA-1jx2A:
undetectable		 2bxcA-1jx2A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 11 ILE A 291
PHE A 441
TYR A 437
ARG A 278
GLY A 237
 None
 1.18A 2bxmA-1jx2A:
3.5		 2bxmA-1jx2A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 11 LEU A 295
LEU A 444
PHE A 441
TYR A 437
GLY A 237
 None
 0.94A 2bxmA-1jx2A:
3.5		 2bxmA-1jx2A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2003_1
(SERUM ALBUMIN)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 10 ILE A 291
PHE A 441
TYR A 437
ARG A 278
GLY A 237
 None
 1.27A 2bxqA-1jx2A:
3.2		 2bxqA-1jx2A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 LEU A 318
LEU A 296
ILE A 291
ILE A 359
ALA A 360
 None
 0.98A 2bxqA-1jx2A:
3.2		 2bxqA-1jx2A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 ASP A 430
VAL A 433
ALA A 360
VAL A 279
TYR A 293
 None
 1.41A 2g72A-1jx2A:
undetectable		 2g72A-1jx2A:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_1
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 PHE A 335
ALA A 235
GLY A 237
THR A 338
LEU A 622
 None
 0.99A 2hw2A-1jx2A:
0.0		 2hw2A-1jx2A:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 ILE A 359
VAL A 618
TRP A 443
LEU A 622
PHE A 236
 None
 1.23A 2jj8C-1jx2A:
undetectable		 2jj8C-1jx2A:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 LEU A 908
LEU A 849
LEU A 920
ILE A 883
VAL A 960
 None
 1.09A 2pnjA-1jx2A:
undetectable		 2pnjA-1jx2A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 LEU A 908
LEU A 849
LEU A 920
ILE A 883
VAL A 989
 None
 1.08A 2pnjA-1jx2A:
undetectable		 2pnjA-1jx2A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_A_LDPA501_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		4 / 7 GLU A 767
GLY A 760
GLN A 761
PHE A 712
 None
 1.02A 2qmzA-1jx2A:
undetectable
2qmzB-1jx2A:
3.8		 2qmzA-1jx2A:
12.94
2qmzB-1jx2A:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		4 / 7 GLY A 438
GLY A 361
PHE A 611
PHE A 623
 None
 0.89A 2qwxA-1jx2A:
4.1
2qwxB-1jx2A:
3.6		 2qwxA-1jx2A:
12.93
2qwxB-1jx2A:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RIW_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 10 ALA A 403
LEU A 436
LEU A 365
LEU A 400
LEU A 432
 None
 1.07A 2riwA-1jx2A:
0.0
2riwB-1jx2A:
0.0		 2riwA-1jx2A:
15.06
2riwB-1jx2A:
3.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_GLYA333_0
(CHOLOYLGLYCINE
HYDROLASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		3 / 3 ASN A 109
ASN A  89
ARG A  55
 None
 0.89A 2rlcA-1jx2A:
0.0		 2rlcA-1jx2A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_1
(AAC(6')-IB)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 GLY A 999
TYR A1051
LEU A1006
GLU A1004
VAL A1005
 None
 1.42A 2vqyA-1jx2A:
0.0		 2vqyA-1jx2A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN6_A_T44A1370_1
(THYROXINE-BINDING
GLOBULIN)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 10 ALA A 403
LEU A 436
LEU A 365
LEU A 400
LEU A 432
 None
 1.10A 2xn6A-1jx2A:
0.0
2xn6B-1jx2A:
0.0		 2xn6A-1jx2A:
15.27
2xn6B-1jx2A:
3.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN7_A_T44A1355_1
(THYROXINE-BINDING
GLOBULIN)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 10 ALA A 403
LEU A 436
LEU A 365
LEU A 400
LEU A 432
 None
 1.11A 2xn7A-1jx2A:
0.0
2xn7B-1jx2A:
0.0		 2xn7A-1jx2A:
15.27
2xn7B-1jx2A:
3.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_1
(WNT INHIBITORY
FACTOR 1)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		4 / 5 ILE A 337
PRO A 231
VAL A 392
PHE A 236
 None
 1.28A 2ygnA-1jx2A:
0.0		 2ygnA-1jx2A:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		4 / 8 GLY A 691
ASN A 690
PHE A 469
ARG A 665
 None
 1.39A 3ccfA-1jx2A:
undetectable		 3ccfA-1jx2A:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 10 ILE A 362
ILE A 358
VAL A 618
LYS A 621
LEU A 432
 None
 1.24A 3em0A-1jx2A:
0.0		 3em0A-1jx2A:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_2
(FIV PROTEASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 9 GLY A 298
ALA A 299
MET A 353
ILE A 291
LEU A 309
 None
 0.93A 3ogpB-1jx2A:
undetectable		 3ogpB-1jx2A:
7.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_A_KKKA413_1
(FLAVOHEMOGLOBIN)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		4 / 8 ILE A 256
ALA A 208
LEU A 207
LEU A 186
 None
 0.79A 3ozwA-1jx2A:
undetectable		 3ozwA-1jx2A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		4 / 6 THR A 734
GLN A 731
TYR A 709
ILE A 707
 None
 1.11A 3peoG-1jx2A:
undetectable		 3peoG-1jx2A:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		4 / 8 LEU A 318
GLN A 282
TYR A 293
PHE A 292
 None
 1.31A 3po7A-1jx2A:
undetectable		 3po7A-1jx2A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_1
(ENDOTHIAPEPSIN)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 GLY A 438
LEU A 233
PHE A 292
ILE A 359
ILE A 358
 None
 0.97A 3pwwA-1jx2A:
undetectable		 3pwwA-1jx2A:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL0_A_FOLA160_0
(DIHYDROFOLATE
REDUCTASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 ALA A 112
MET A 102
LEU A 687
PHE A 114
LEU A 678
 None
 1.12A 3ql0A-1jx2A:
undetectable		 3ql0A-1jx2A:
8.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_B_ACTB4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		3 / 3 GLY A 193
GLY A 195
THR A 197
 ADP  A1203 (-3.4A)
ADP  A1203 (-3.1A)
MG  A1202 ( 3.1A)
 0.45A 3si7B-1jx2A:
undetectable		 3si7B-1jx2A:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		4 / 5 PHE A 114
TYR A 121
LEU A 108
ARG A 120
 None
 0.82A 3sudD-1jx2A:
0.0		 3sudD-1jx2A:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		3 / 3 PRO A 962
THR A 961
LEU A 967
 None
 0.72A 3ttrA-1jx2A:
undetectable		 3ttrA-1jx2A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		4 / 7 ILE A 291
PHE A 236
GLN A 294
PHE A 335
 None
 1.26A 3tvxB-1jx2A:
undetectable		 3tvxB-1jx2A:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		3 / 3 PHE A 472
SER A 467
SER A 192
 None
None
ADP  A1203 ( 4.7A)
 0.84A 3ufgB-1jx2A:
undetectable		 3ufgB-1jx2A:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		4 / 5 VAL A 113
LEU A 693
ILE A 696
VAL A 135
 None
 0.89A 4a9kB-1jx2A:
undetectable		 4a9kB-1jx2A:
8.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		3 / 3 ARG A 157
ARG A 158
ILE A  15
 None
 0.86A 4b7qA-1jx2A:
undetectable		 4b7qA-1jx2A:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 GLU A 487
ASN A 483
PHE A 469
LEU A 558
ILE A 528
 None
 1.17A 4djeA-1jx2A:
3.1		 4djeA-1jx2A:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 11 ILE A 668
ALA A 194
GLY A 195
GLU A 198
ASN A 238
 None
ADP  A1203 (-4.3A)
ADP  A1203 (-3.1A)
ADP  A1203 (-4.1A)
None
 1.15A 4e47A-1jx2A:
undetectable		 4e47A-1jx2A:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 11 ILE A 668
ALA A 194
GLY A 195
GLU A 198
ASN A 238
 None
ADP  A1203 (-4.3A)
ADP  A1203 (-3.1A)
ADP  A1203 (-4.1A)
None
 1.18A 4e47B-1jx2A:
undetectable		 4e47B-1jx2A:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_C_SAMC800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 11 ILE A 668
ALA A 194
GLY A 195
GLU A 198
ASN A 238
 None
ADP  A1203 (-4.3A)
ADP  A1203 (-3.1A)
ADP  A1203 (-4.1A)
None
 1.13A 4e47C-1jx2A:
undetectable		 4e47C-1jx2A:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 9 PHE A 562
ILE A 536
ASP A 551
LEU A 554
PHE A 579
 None
 1.49A 4eb4C-1jx2A:
0.0		 4eb4C-1jx2A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 11 ILE A 668
ALA A 194
GLY A 195
GLU A 198
ASN A 238
 None
ADP  A1203 (-4.3A)
ADP  A1203 (-3.1A)
ADP  A1203 (-4.1A)
None
 1.20A 4jdsA-1jx2A:
undetectable		 4jdsA-1jx2A:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 11 ILE A 668
ALA A 194
GLY A 195
GLU A 198
ASN A 238
 None
ADP  A1203 (-4.3A)
ADP  A1203 (-3.1A)
ADP  A1203 (-4.1A)
None
 1.18A 4jdsB-1jx2A:
undetectable		 4jdsB-1jx2A:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_C_SAMC401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 11 ILE A 668
ALA A 194
GLY A 195
GLU A 198
ASN A 238
 None
ADP  A1203 (-4.3A)
ADP  A1203 (-3.1A)
ADP  A1203 (-4.1A)
None
 1.16A 4jdsC-1jx2A:
undetectable		 4jdsC-1jx2A:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 ILE A 668
ALA A 194
GLY A 195
GLU A 198
ASN A 238
 None
ADP  A1203 (-4.3A)
ADP  A1203 (-3.1A)
ADP  A1203 (-4.1A)
None
 1.12A 4jlgA-1jx2A:
undetectable		 4jlgA-1jx2A:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 LEU A1067
GLY A 988
ALA A 959
THR A 961
VAL A 825
 None
 1.11A 4nkxC-1jx2A:
undetectable		 4nkxC-1jx2A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 LEU A1067
GLY A 988
ALA A 959
THR A 961
VAL A 825
 None
 1.08A 4nkxD-1jx2A:
undetectable		 4nkxD-1jx2A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_2
(ASPARTYL PROTEASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 LEU A 920
ILE A 956
ILE A1018
VAL A 814
ILE A 812
 None
 0.93A 4q1yB-1jx2A:
undetectable		 4q1yB-1jx2A:
6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		4 / 6 ALA A 267
GLY A 462
ILE A 226
VAL A 203
 None
 0.81A 4r21A-1jx2A:
1.5		 4r21A-1jx2A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 LEU A 307
LEU A 432
GLU A 303
PHE A 292
LEU A 318
 None
 1.10A 4retA-1jx2A:
2.5		 4retA-1jx2A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		4 / 4 ASN A 690
VAL A 135
THR A 189
ILE A 188
 None
 0.99A 4retA-1jx2A:
2.5		 4retA-1jx2A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 LEU A 307
LEU A 432
GLU A 303
PHE A 292
LEU A 318
 None
 1.10A 4retC-1jx2A:
2.2		 4retC-1jx2A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		4 / 4 ASN A 690
VAL A 135
THR A 189
ILE A 188
 None
 0.99A 4retC-1jx2A:
2.5		 4retC-1jx2A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		4 / 4 ILE A 792
ASN A 793
ILE A 848
VAL A 921
 None
 1.31A 4uy87-1jx2A:
undetectable		 4uy87-1jx2A:
2.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		3 / 3 LEU A 436
VAL A 618
ASP A 616
 None
 0.66A 4y8wC-1jx2A:
1.3		 4y8wC-1jx2A:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 11 ILE A 668
ALA A 194
GLY A 195
GLU A 198
ASN A 238
 None
ADP  A1203 (-4.3A)
ADP  A1203 (-3.1A)
ADP  A1203 (-4.1A)
None
 1.07A 5ayfA-1jx2A:
undetectable		 5ayfA-1jx2A:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ENT_C_MIYC901_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 9 SER A 824
PHE A1017
GLY A1019
GLU A1041
ALA A1002
 None
 1.24A 5entC-1jx2A:
0.0		 5entC-1jx2A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 11 ILE A 990
PHE A1017
THR A 965
VAL A1010
LEU A 973
 None
 1.29A 5jkwA-1jx2A:
0.0		 5jkwA-1jx2A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 ALA A 388
PRO A 397
PHE A 393
MET A 405
ILE A 368
 None
 1.35A 5ljbA-1jx2A:
undetectable		 5ljbA-1jx2A:
7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 ILE A 264
GLY A 266
PHE A 460
TYR A 174
ALA A 211
 None
 1.03A 5n0oA-1jx2A:
1.5		 5n0oA-1jx2A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 ILE A 264
GLY A 266
PHE A 460
TYR A 174
ALA A 211
 None
 1.04A 5n0oB-1jx2A:
1.7		 5n0oB-1jx2A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 ILE A 264
GLY A 266
PHE A 460
TYR A 174
ALA A 211
 None
 1.04A 5n0rA-1jx2A:
0.0		 5n0rA-1jx2A:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 ILE A 264
GLY A 266
PHE A 460
TYR A 174
ALA A 211
 None
 1.05A 5n0sA-1jx2A:
0.1		 5n0sA-1jx2A:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 ILE A 264
GLY A 266
PHE A 460
TYR A 174
ALA A 211
 None
 1.04A 5n0tA-1jx2A:
0.0		 5n0tA-1jx2A:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 ILE A 264
GLY A 266
PHE A 460
TYR A 174
ALA A 211
 None
 1.05A 5n0tB-1jx2A:
0.0		 5n0tB-1jx2A:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 ILE A 264
GLY A 266
PHE A 460
TYR A 174
ALA A 211
 None
 1.05A 5n0wA-1jx2A:
undetectable		 5n0wA-1jx2A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 ILE A 264
GLY A 266
PHE A 460
TYR A 174
ALA A 211
 None
 1.05A 5n0wB-1jx2A:
undetectable		 5n0wB-1jx2A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 ILE A 264
GLY A 266
PHE A 460
TYR A 174
ALA A 211
 None
 1.04A 5n0xA-1jx2A:
0.0		 5n0xA-1jx2A:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 ILE A 264
GLY A 266
PHE A 460
TYR A 174
ALA A 211
 None
 1.03A 5n0xB-1jx2A:
0.0		 5n0xB-1jx2A:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 ILE A 264
GLY A 266
PHE A 460
TYR A 174
ALA A 211
 None
 1.04A 5n4iA-1jx2A:
0.3		 5n4iA-1jx2A:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA307_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		4 / 5 ASP A 343
PRO A 231
GLU A 334
THR A 338
 None
 1.38A 5uxcA-1jx2A:
1.1		 5uxcA-1jx2A:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_I_PACI1_0
(SERINE PROTEASE NS3
SERINE PROTEASE
SUBUNIT NS2B
PEPTIDE
PAC-DLY-DLY-DAR)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		3 / 3 VAL A 324
TYR A 293
GLU A 313
 None
 0.99A 5zmqD-1jx2A:
undetectable
5zmqE-1jx2A:
undetectable		 5zmqD-1jx2A:
10.65
5zmqE-1jx2A:
4.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_A_P2EA1201_0
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 THR A 658
THR A 655
LEU A 489
SER A 185
GLN A 184
 None
 1.42A 6ak3A-1jx2A:
1.6		 6ak3A-1jx2A:
5.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_0
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 THR A 658
THR A 655
LEU A 489
SER A 185
GLN A 184
 None
 1.41A 6ak3B-1jx2A:
1.6		 6ak3B-1jx2A:
5.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		4 / 5 VAL A 989
THR A 991
LEU A1067
VAL A 916
 None
 1.02A 6bqgA-1jx2A:
2.0		 6bqgA-1jx2A:
5.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 12 MET A 353
SER A 390
VAL A 395
LEU A 309
ALA A 360
 None
 1.16A 6djzC-1jx2A:
0.9		 6djzC-1jx2A:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 9 LEU A 540
ASP A 541
GLY A 530
ILE A 528
PHE A 477
 None
 1.13A 6ebpA-1jx2A:
0.0		 6ebpA-1jx2A:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 10 LEU A 540
ASP A 541
GLY A 530
ILE A 528
PHE A 477
 None
 1.10A 6ebpB-1jx2A:
0.1		 6ebpB-1jx2A:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 10 LEU A 540
ASP A 541
GLY A 530
ILE A 528
PHE A 477
 None
 1.09A 6ebpC-1jx2A:
undetectable		 6ebpC-1jx2A:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 11 LEU A 540
ASP A 541
GLY A 530
ILE A 528
PHE A 477
 None
 1.07A 6ebzA-1jx2A:
undetectable		 6ebzA-1jx2A:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 11 LEU A 540
ASP A 541
GLY A 530
ILE A 528
PHE A 477
 None
 1.04A 6ebzB-1jx2A:
undetectable		 6ebzB-1jx2A:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 11 LEU A 540
ASP A 541
GLY A 530
ILE A 528
PHE A 477
 None
 1.00A 6ebzD-1jx2A:
undetectable		 6ebzD-1jx2A:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 10 ILE A1075
VAL A1086
LEU A1082
LEU A 809
LEU A 780
 None
 1.02A 6f6nA-1jx2A:
0.0
6f6nB-1jx2A:
0.0		 6f6nA-1jx2A:
5.89
6f6nB-1jx2A:
5.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA826_0
(GEPHYRIN)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		3 / 3 HIS A  16
ARG A 157
ILE A  15
 None
 0.69A 6fgdA-1jx2A:
undetectable		 6fgdA-1jx2A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 11 LEU A 540
ASP A 541
GLY A 530
ILE A 528
PHE A 477
 None
 0.86A 6gp2A-1jx2A:
undetectable		 6gp2A-1jx2A:
5.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		5 / 11 LEU A 540
ASP A 541
GLY A 530
ILE A 528
PHE A 477
 None
 0.87A 6gp2B-1jx2A:
undetectable		 6gp2B-1jx2A:
5.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		4 / 6 THR A 919
LEU A 920
THR A 852
LEU A 908
 None
 1.23A 6mvxA-1jx2A:
undetectable
6mvxB-1jx2A:
2.7
6mvxC-1jx2A:
1.1		 6mvxA-1jx2A:
13.84
6mvxB-1jx2A:
13.84
6mvxC-1jx2A:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_1
(ADENOSINE DEAMINASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		4 / 4 HIS A 364
LEU A 318
TYR A 293
GLY A 311
 None
 1.33A 6n91A-1jx2A:
2.5		 6n91A-1jx2A:
4.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_1
(ADENOSINE DEAMINASE)		 1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A
(Dictyostelium
discoideum) 		4 / 4 HIS A 364
LEU A 318
TYR A 293
GLY A 311
 None
 1.35A 6n91B-1jx2A:
2.5		 6n91B-1jx2A:
4.73