SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jx7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_A_BEZA1501_0
(ANTHRANILATE
SYNTHASE)		 1jx7 HYPOTHETICAL PROTEIN
YCHN
(Escherichia
coli) 		5 / 11 ILE A  93
GLY A  95
THR A  69
GLU A  97
LEU A  41
 None
 1.37A 1i7qA-1jx7A:
undetectable		 1i7qA-1jx7A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1jx7 HYPOTHETICAL PROTEIN
YCHN
(Escherichia
coli) 		3 / 3 SER A  17
ASP A  44
CYH A  81
 None
 1.07A 2br4E-1jx7A:
undetectable		 2br4E-1jx7A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		 1jx7 HYPOTHETICAL PROTEIN
YCHN
(Escherichia
coli) 		4 / 6 LEU A  77
LEU A  41
ILE A  87
ARG A  85
 None
 1.16A 2rlfB-1jx7A:
undetectable
2rlfC-1jx7A:
0.0		 2rlfB-1jx7A:
16.24
2rlfC-1jx7A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1jx7 HYPOTHETICAL PROTEIN
YCHN
(Escherichia
coli) 		5 / 12 ALA A   8
LEU A  68
ALA A  48
VAL A  75
VAL A  96
 None
 0.98A 4nkvB-1jx7A:
undetectable		 4nkvB-1jx7A:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1jx7 HYPOTHETICAL PROTEIN
YCHN
(Escherichia
coli) 		6 / 9 ALA A  48
ALA A   8
SER A  21
SER A  17
ALA A  11
SER A  15
 None
 1.35A 4twdA-1jx7A:
0.0
4twdB-1jx7A:
0.0
4twdC-1jx7A:
0.0
4twdD-1jx7A:
0.0
4twdE-1jx7A:
0.0		 4twdA-1jx7A:
17.59
4twdB-1jx7A:
17.59
4twdC-1jx7A:
17.59
4twdD-1jx7A:
17.59
4twdE-1jx7A:
17.59