SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jxk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		5 / 12 HIS A 101
ASP A 197
LEU A 162
LEU A 165
GLY A 104
 None
 1.07A 1d4fD-1jxkA:
0.7		 1d4fD-1jxkA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		7 / 12 TYR A  62
LEU A 162
LEU A 165
ASP A 197
ALA A 198
HIS A 299
ASP A 300
 None
 0.71A 1dedA-1jxkA:
27.6		 1dedA-1jxkA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		8 / 12 TYR A  62
LEU A 165
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
None
CL  A 493 (-4.0A)
None
None
None
None
None
 0.80A 1dedB-1jxkA:
25.0		 1dedB-1jxkA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		5 / 12 TYR A  62
GLN A  63
HIS A 201
HIS A 299
ASP A 300
 None
 1.08A 1eswA-1jxkA:
11.6		 1eswA-1jxkA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		3 / 3 ASN A  87
PHE A  79
VAL A 191
 None
 0.87A 1kijA-1jxkA:
0.0		 1kijA-1jxkA:
21.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		8 / 12 TRP A  58
GLN A  63
HIS A 101
GLY A 164
ALA A 198
GLU A 233
ILE A 235
ASP A 300
 None
 0.41A 1kxhA-1jxkA:
50.1		 1kxhA-1jxkA:
46.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		6 / 12 TRP A  58
HIS A 101
GLY A 104
ALA A 198
GLU A 233
ASP A 300
 None
 1.08A 1kxhA-1jxkA:
50.1		 1kxhA-1jxkA:
46.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		3 / 3 TRP A  59
TYR A  62
LEU A 165
 None
 0.24A 1kxhA-1jxkA:
50.1		 1kxhA-1jxkA:
46.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_B_AG2B7001_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		4 / 6 ILE A 307
GLU A 380
ARG A 267
ASP A 312
 None
 1.00A 1mt1B-1jxkA:
0.0
1mt1C-1jxkA:
undetectable		 1mt1B-1jxkA:
11.41
1mt1C-1jxkA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		9 / 12 TRP A  58
TYR A  62
HIS A 101
ARG A 195
ASP A 197
LYS A 200
GLU A 233
HIS A 299
ASP A 300
 None
None
None
CL  A 493 (-4.0A)
None
None
None
None
None
 0.70A 1mxdA-1jxkA:
29.2		 1mxdA-1jxkA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		5 / 12 ILE A  24
ALA A  25
ARG A  85
ILE A 367
HIS A 381
 None
 1.08A 1xzxX-1jxkA:
0.0		 1xzxX-1jxkA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_A_RBFA300_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		5 / 11 TYR A 258
GLY A 259
ILE A 266
HIS A 326
ALA A 319
 None
 1.20A 2a58A-1jxkA:
undetectable
2a58E-1jxkA:
undetectable		 2a58A-1jxkA:
16.04
2a58E-1jxkA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		5 / 12 ILE A 266
HIS A 326
ALA A 319
TYR A 258
GLY A 259
 None
 1.22A 2a58A-1jxkA:
undetectable
2a58B-1jxkA:
undetectable		 2a58A-1jxkA:
16.04
2a58B-1jxkA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		5 / 12 ILE A 266
HIS A 326
ALA A 319
TYR A 258
GLY A 259
 None
 1.20A 2a58B-1jxkA:
undetectable
2a58C-1jxkA:
undetectable		 2a58B-1jxkA:
16.04
2a58C-1jxkA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_D_RBFD303_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		5 / 11 ILE A 266
HIS A 326
ALA A 319
TYR A 258
GLY A 259
 None
 1.21A 2a58C-1jxkA:
undetectable
2a58D-1jxkA:
undetectable		 2a58C-1jxkA:
16.04
2a58D-1jxkA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		5 / 12 ILE A 266
HIS A 326
ALA A 319
TYR A 258
GLY A 259
 None
 1.22A 2a58D-1jxkA:
undetectable
2a58E-1jxkA:
undetectable		 2a58D-1jxkA:
16.04
2a58E-1jxkA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		5 / 12 ILE A  24
ALA A  25
ARG A  85
ILE A 367
HIS A 381
 None
 1.13A 2h77A-1jxkA:
0.0		 2h77A-1jxkA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_1
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		4 / 5 PRO A 130
ALA A 128
ASP A 135
ASP A 125
 None
 1.20A 2nyuB-1jxkA:
undetectable		 2nyuB-1jxkA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWC_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		6 / 11 TYR A  62
GLN A  63
ASP A 197
HIS A 299
ASP A 300
TRP A  58
 None
 1.03A 2owcA-1jxkA:
13.4		 2owcA-1jxkA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWW_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		6 / 11 TYR A  62
GLN A  63
ASP A 197
HIS A 299
ASP A 300
TRP A  58
 None
 1.02A 2owwA-1jxkA:
13.4		 2owwA-1jxkA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
CL  A 493 (-4.0A)
None
None
None
None
None
 0.58A 3aicA-1jxkA:
4.7		 3aicA-1jxkA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
CL  A 493 (-4.0A)
None
None
None
None
None
 0.57A 3aicB-1jxkA:
4.3		 3aicB-1jxkA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		7 / 12 ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
TYR A  62
 CL  A 493 (-4.0A)
None
None
None
None
None
None
 0.59A 3aicC-1jxkA:
11.2		 3aicC-1jxkA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
CL  A 493 (-4.0A)
None
None
None
None
None
 0.61A 3aicD-1jxkA:
3.5		 3aicD-1jxkA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
CL  A 493 (-4.0A)
None
None
None
None
None
 0.59A 3aicE-1jxkA:
3.0		 3aicE-1jxkA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
CL  A 493 (-4.0A)
None
None
None
None
None
 0.60A 3aicF-1jxkA:
10.9		 3aicF-1jxkA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
CL  A 493 (-4.0A)
None
None
None
None
None
 0.56A 3aicG-1jxkA:
3.7		 3aicG-1jxkA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
CL  A 493 (-4.0A)
None
None
None
None
None
 0.63A 3aicH-1jxkA:
3.5		 3aicH-1jxkA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_0
(UNCHARACTERIZED
PROTEIN RPA2492)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		5 / 12 PRO A  57
GLY A 164
SER A 163
CYH A 103
HIS A 101
 None
 1.20A 3e23A-1jxkA:
undetectable		 3e23A-1jxkA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		5 / 12 VAL A 234
TYR A  67
ILE A 230
VAL A 175
TYR A 131
 None
None
PCA  A   1 ( 4.5A)
None
None
 1.25A 3g8iA-1jxkA:
0.0		 3g8iA-1jxkA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		4 / 6 VAL A  91
VAL A 390
ILE A  13
ARG A  30
 None
 1.03A 3pyyA-1jxkA:
undetectable		 3pyyA-1jxkA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		4 / 5 PHE A 229
PHE A 330
ILE A  13
GLY A  38
 PCA  A   1 ( 4.7A)
None
None
None
 1.01A 4ejjC-1jxkA:
undetectable		 4ejjC-1jxkA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		4 / 8 GLY A  38
LEU A  16
VAL A  42
TYR A  94
 None
 0.92A 4fgzA-1jxkA:
undetectable		 4fgzA-1jxkA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE0_A_40LA1101_0
(PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT DELTA
ISOFORM)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		5 / 12 ILE A 196
VAL A  98
ASP A 167
ASN A 137
ILE A 179
 None
None
CA  A 492 (-2.3A)
None
None
 1.31A 4xe0A-1jxkA:
undetectable		 4xe0A-1jxkA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		5 / 12 ARG A 195
ASP A 197
GLU A 233
HIS A 299
ASP A 300
 CL  A 493 (-4.0A)
None
None
None
None
 0.38A 5csyB-1jxkA:
5.1		 5csyB-1jxkA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		5 / 7 PHE A 330
GLY A  36
VAL A 333
ILE A  13
VAL A  14
 None
 1.26A 5ik1A-1jxkA:
undetectable		 5ik1A-1jxkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		4 / 5 TYR A 444
ILE A 462
GLY A 420
PHE A 421
 None
 0.93A 5kmdC-1jxkA:
undetectable
5kmdD-1jxkA:
undetectable		 5kmdC-1jxkA:
18.18
5kmdD-1jxkA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMF_A_6U9A1301_1
(ION TRANSPORT
PROTEIN)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		4 / 6 GLY A 420
PHE A 421
TYR A 444
ILE A 462
 None
 0.95A 5kmfA-1jxkA:
undetectable
5kmfC-1jxkA:
0.0		 5kmfA-1jxkA:
18.18
5kmfC-1jxkA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_F_RBFF201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		4 / 7 LEU A 324
VAL A 378
TYR A 316
SER A 336
 None
 1.31A 5umwA-1jxkA:
0.0
5umwF-1jxkA:
0.0		 5umwA-1jxkA:
11.60
5umwF-1jxkA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		8 / 12 TRP A  58
TYR A  62
GLU A 240
ASP A 197
LYS A 200
HIS A 201
HIS A 299
ASP A 300
 None
 1.14A 6ag0A-1jxkA:
26.6		 6ag0A-1jxkA:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		7 / 12 TRP A  58
TYR A  62
GLU A 240
TYR A 151
LYS A 200
HIS A 299
ASP A 300
 None
 1.39A 6ag0A-1jxkA:
26.6		 6ag0A-1jxkA:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		9 / 12 TRP A  58
TYR A  62
HIS A 101
LEU A 162
ASP A 197
LYS A 200
HIS A 201
HIS A 299
ASP A 300
 None
 0.83A 6ag0A-1jxkA:
26.6		 6ag0A-1jxkA:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		6 / 12 TRP A  58
TYR A  62
LEU A 165
ASP A 197
HIS A 299
ASP A 300
 None
 1.39A 6ag0A-1jxkA:
26.6		 6ag0A-1jxkA:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		6 / 12 GLU A 240
ASP A 197
LYS A 200
HIS A 201
HIS A 299
ASP A 300
 None
 1.15A 6ag0C-1jxkA:
26.6		 6ag0C-1jxkA:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		5 / 12 GLU A 240
TYR A 151
LYS A 200
HIS A 299
ASP A 300
 None
 1.37A 6ag0C-1jxkA:
26.6		 6ag0C-1jxkA:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		6 / 12 LEU A 162
ASP A 197
LYS A 200
HIS A 201
HIS A 299
ASP A 300
 None
 0.62A 6ag0C-1jxkA:
26.6		 6ag0C-1jxkA:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		6 / 12 TRP A  58
GLU A 240
ASP A 197
LYS A 200
HIS A 201
HIS A 299
 None
 1.21A 6ag0C-1jxkA:
26.6		 6ag0C-1jxkA:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		5 / 12 TRP A  58
GLU A 240
TYR A 151
LYS A 200
HIS A 299
 None
 1.48A 6ag0C-1jxkA:
26.6		 6ag0C-1jxkA:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		6 / 12 TRP A  58
LEU A 162
ASP A 197
LYS A 200
HIS A 201
HIS A 299
 None
 0.77A 6ag0C-1jxkA:
26.6		 6ag0C-1jxkA:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		3 / 3 GLN A 232
TYR A 247
ASN A 250
 None
 1.07A 6dwdC-1jxkA:
0.0		 6dwdC-1jxkA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_H_PCFH604_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 1jxk ALPHA-AMYLASE,
SALIVARY
(Homo
sapiens) 		5 / 8 GLY A 420
PHE A 421
HIS A 486
GLY A 442
ALA A 470
 None
 1.42A 6hu9H-1jxkA:
undetectable
6hu9e-1jxkA:
undetectable		 6hu9H-1jxkA:
9.81
6hu9e-1jxkA:
11.84