SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jy5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 1jy5 CALSEPRRP
(Calystegia
sepium) 		5 / 12 PRO A  80
GLY A  39
THR A  41
SER A 137
ILE A 206
 None
 1.19A 3iv6A-1jy5A:
undetectable		 3iv6A-1jy5A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 1jy5 CALSEPRRP
(Calystegia
sepium) 		5 / 12 PRO A  80
GLY A  39
THR A  41
ILE A 206
ARG A  33
 None
 1.18A 3iv6C-1jy5A:
undetectable		 3iv6C-1jy5A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 1jy5 CALSEPRRP
(Calystegia
sepium) 		5 / 12 PRO A  80
GLY A  39
THR A  41
SER A 137
ILE A 206
 None
 1.20A 3iv6C-1jy5A:
undetectable		 3iv6C-1jy5A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 1jy5 CALSEPRRP
(Calystegia
sepium) 		3 / 3 ASP A  48
TYR A   7
TRP A  46
 None
 1.10A 4p7nA-1jy5A:
undetectable		 4p7nA-1jy5A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_2
(CYP51 VARIANT1)		 1jy5 CALSEPRRP
(Calystegia
sepium) 		3 / 3 PRO A 199
LEU A 204
SER A 172
 None
 0.72A 5fsaB-1jy5A:
0.0		 5fsaB-1jy5A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 1jy5 CALSEPRRP
(Calystegia
sepium) 		5 / 12 ILE A 132
VAL A 167
VAL A 168
PHE A  40
THR A   9
 None
 1.15A 6b52A-1jy5A:
undetectable		 6b52A-1jy5A:
22.76