SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jya'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)		 1jya YOPE REGULATOR
(Yersinia
pseudotuberculos
is) 		5 / 12 PRO A  94
LEU A  74
SER A 102
LEU A  98
ILE A  73
 None
 1.36A 1lbcA-1jyaA:
undetectable
1lbcC-1jyaA:
undetectable		 1lbcA-1jyaA:
17.74
1lbcC-1jyaA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LBC_C_CYZC331_1
(GLUTAMINE RECEPTOR 2)		 1jya YOPE REGULATOR
(Yersinia
pseudotuberculos
is) 		5 / 12 ILE A  73
PRO A  94
LEU A  74
SER A 102
LEU A  98
 None
 1.43A 1lbcA-1jyaA:
undetectable
1lbcC-1jyaA:
undetectable		 1lbcA-1jyaA:
17.74
1lbcC-1jyaA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H6T_A_CYZA265_1
(GLUTAMATE RECEPTOR 2)		 1jya YOPE REGULATOR
(Yersinia
pseudotuberculos
is) 		5 / 11 PRO A  94
LEU A  74
SER A 102
LEU A  98
ILE A  73
 None
 1.41A 3h6tA-1jyaA:
undetectable
3h6tC-1jyaA:
undetectable		 3h6tA-1jyaA:
17.74
3h6tC-1jyaA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_1
(HIV-1 PROTEASE)		 1jya YOPE REGULATOR
(Yersinia
pseudotuberculos
is) 		5 / 9 LEU A  74
ASN A  91
VAL A 111
ILE A  38
THR A 105
 None
 1.19A 3spkA-1jyaA:
undetectable		 3spkA-1jyaA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_1
(HIV-1 PROTEASE)		 1jya YOPE REGULATOR
(Yersinia
pseudotuberculos
is) 		5 / 7 LEU A  74
ASN A  91
VAL A 111
ILE A  27
THR A 105
 None
 1.33A 4eyrA-1jyaA:
undetectable		 4eyrA-1jyaA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 1jya YOPE REGULATOR
(Yersinia
pseudotuberculos
is) 		4 / 5 LEU A  98
LEU A  95
MET A  48
TYR A 104
 None
 1.37A 5uc3A-1jyaA:
0.0		 5uc3A-1jyaA:
20.17